{
  "url": "https://dantelabs.com/traits/abnormal-circulating-methionine-concentration",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-methionine-concentration",
    "id": "HP:0010901",
    "name": "Abnormal circulating methionine concentration",
    "definition": "Any deviation from the normal concentration of methionine in the blood circulation.",
    "synonyms": [
      "Abnormality of methionine metabolism"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-aspartate-family-amino-acid-concentration",
        "name": "Abnormal circulating aspartate family amino acid concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-aspartate-family-amino-acid-concentration"
      },
      {
        "slug": "abnormal-circulating-sulfur-containing-amino-acid-concentration",
        "name": "Abnormal circulating sulfur-containing amino acid concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-sulfur-containing-amino-acid-concentration"
      }
    ],
    "narrower": [
      {
        "slug": "hypermethioninemia",
        "name": "Increased methionine in blood",
        "genes": 9,
        "url": "https://dantelabs.com/traits/hypermethioninemia"
      },
      {
        "slug": "hypomethioninemia",
        "name": "Decreased plasma methionine",
        "genes": 8,
        "url": "https://dantelabs.com/traits/hypomethioninemia"
      }
    ],
    "genes": [
      {
        "slug": "ahcy",
        "symbol": "AHCY",
        "hgnc": "HGNC:343",
        "name": "adenosylhomocysteinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahcy"
      }
    ]
  }
}