{
  "url": "https://dantelabs.com/traits/abnormal-abdominal-wall-morphology",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "abnormal-abdominal-wall-morphology",
    "id": "HP:0004298",
    "name": "Abnormality of the abdominal wall",
    "label": "Abnormal abdominal wall morphology",
    "definition": "The presence of any abnormality affecting the abdominal wall.",
    "synonyms": [
      "Abnormality of external features of the abdomen"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "narrower": [
      {
        "slug": "prune-belly",
        "name": "Prune belly",
        "genes": 4,
        "url": "https://dantelabs.com/traits/prune-belly"
      },
      {
        "slug": "abdominal-wall-defect",
        "name": "Abdominal wall defect",
        "genes": 3,
        "url": "https://dantelabs.com/traits/abdominal-wall-defect"
      },
      {
        "slug": "abnormal-umbilicus-morphology",
        "name": "Abnormal belly button",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-umbilicus-morphology"
      },
      {
        "slug": "redundant-umbilical-skin",
        "name": "Redundant umbilical skin",
        "genes": 2,
        "url": "https://dantelabs.com/traits/redundant-umbilical-skin"
      },
      {
        "slug": "abnormal-morphology-of-the-abdominal-musculature",
        "name": "Abnormal morphology of the abdominal musculature",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-morphology-of-the-abdominal-musculature"
      },
      {
        "slug": "exstrophy",
        "name": "Exstrophy",
        "genes": 0,
        "url": "https://dantelabs.com/traits/exstrophy"
      }
    ],
    "genes": [
      {
        "slug": "apc",
        "symbol": "APC",
        "hgnc": "HGNC:583",
        "name": "APC regulator of Wnt signaling pathway",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apc"
      },
      {
        "slug": "ctnnb1",
        "symbol": "CTNNB1",
        "hgnc": "HGNC:2514",
        "name": "catenin beta 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctnnb1"
      },
      {
        "slug": "sts",
        "symbol": "STS",
        "hgnc": "HGNC:11425",
        "name": "steroid sulfatase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sts"
      },
      {
        "slug": "usp9x",
        "symbol": "USP9X",
        "hgnc": "HGNC:12632",
        "name": "ubiquitin specific peptidase 9 X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp9x"
      },
      {
        "slug": "b3gat3",
        "symbol": "B3GAT3",
        "hgnc": "HGNC:923",
        "name": "beta-1,3-glucuronyltransferase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/b3gat3"
      },
      {
        "slug": "chst3",
        "symbol": "CHST3",
        "hgnc": "HGNC:1971",
        "name": "carbohydrate sulfotransferase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chst3"
      },
      {
        "slug": "hla-dqa1",
        "symbol": "HLA-DQA1",
        "hgnc": "HGNC:4942",
        "name": "major histocompatibility complex, class II, DQ alpha 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dqa1"
      },
      {
        "slug": "hla-dqb1",
        "symbol": "HLA-DQB1",
        "hgnc": "HGNC:4944",
        "name": "major histocompatibility complex, class II, DQ beta 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dqb1"
      },
      {
        "slug": "masp1",
        "symbol": "MASP1",
        "hgnc": "HGNC:6901",
        "name": "MBL associated serine protease 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/masp1"
      }
    ]
  }
}