{
  "url": "https://dantelabs.com/traits/2-hydroxyglutarate-aciduria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "2-hydroxyglutarate-aciduria",
    "id": "HP:0032278",
    "name": "2-hydroxyglutarate aciduria",
    "definition": "The concentration of 2-hydroxyglutaric acid in the urine, normalized for urine concentration, is above the upper limit of normal.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "elevated-urinary-dicarboxylic-acid-level",
        "name": "Elevated urinary dicarboxylic acid level",
        "url": "https://dantelabs.com/traits/elevated-urinary-dicarboxylic-acid-level"
      }
    ],
    "narrower": [
      {
        "slug": "d-2-hydroxyglutaric-aciduria",
        "name": "D-2-hydroxyglutaric aciduria",
        "genes": 3,
        "url": "https://dantelabs.com/traits/d-2-hydroxyglutaric-aciduria"
      },
      {
        "slug": "l-2-hydroxyglutaric-aciduria",
        "name": "L-2-hydroxyglutaric aciduria",
        "genes": 2,
        "url": "https://dantelabs.com/traits/l-2-hydroxyglutaric-aciduria"
      }
    ],
    "genes": [
      {
        "slug": "coq4",
        "symbol": "COQ4",
        "hgnc": "HGNC:19693",
        "name": "coenzyme Q4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/coq4"
      }
    ]
  }
}