{
  "url": "https://dantelabs.com/traits/trachyonychia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "trachyonychia",
    "id": "HP:0030804",
    "name": "Trachyonychia",
    "definition": "Excessive longitudinal ridging that gives the surface of the nail plate a rough appearance. It results from multiple foci of defective keratinization of the proximal nail matrix.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "nail-dysplasia",
        "name": "Atypical nail growth",
        "url": "https://dantelabs.com/traits/nail-dysplasia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "nfkb2",
        "symbol": "NFKB2",
        "hgnc": "HGNC:7795",
        "name": "nuclear factor kappa B subunit 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfkb2"
      },
      {
        "slug": "fzd6",
        "symbol": "FZD6",
        "hgnc": "HGNC:4044",
        "name": "frizzled class receptor 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fzd6"
      }
    ]
  }
}