{
  "url": "https://dantelabs.com/traits/pansynostosis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "pansynostosis",
    "id": "HP:0011325",
    "name": "Pansynostosis",
    "definition": "Craniosynostosis of all calvarial sutures.",
    "synonyms": [
      "Sysnostosis of all cranial sutures"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "multiple-suture-craniosynostosis",
        "name": "Multiple suture craniosynostosis",
        "url": "https://dantelabs.com/traits/multiple-suture-craniosynostosis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "erf",
        "symbol": "ERF",
        "hgnc": "HGNC:3444",
        "name": "ETS2 repressor factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/erf"
      },
      {
        "slug": "twist1",
        "symbol": "TWIST1",
        "hgnc": "HGNC:12428",
        "name": "twist family bHLH transcription factor 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/twist1"
      }
    ]
  }
}