{
  "url": "https://dantelabs.com/traits/macular-hole",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "macular-hole",
    "id": "HP:0011508",
    "name": "Macular hole",
    "definition": "A macular hole is a full thickness gap in the macula, located in the center of the retina.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-macular-morphology",
        "name": "Abnormal macular morphology",
        "url": "https://dantelabs.com/traits/abnormal-macular-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "full-thickness-macular-hole",
        "name": "Full-thickness macular hole",
        "genes": 3,
        "url": "https://dantelabs.com/traits/full-thickness-macular-hole"
      }
    ],
    "genes": [
      {
        "slug": "hla-a",
        "symbol": "HLA-A",
        "hgnc": "HGNC:4931",
        "name": "major histocompatibility complex, class I, A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-a"
      },
      {
        "slug": "col4a5",
        "symbol": "COL4A5",
        "hgnc": "HGNC:2207",
        "name": "collagen type IV alpha 5 chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a5"
      }
    ]
  }
}