{
  "url": "https://dantelabs.com/traits/large-vessel-vasculitis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "large-vessel-vasculitis",
    "id": "HP:0005310",
    "name": "Large vessel vasculitis",
    "definition": "A type of vasculitis (inflammation of blood vessel walls) affecting large arteries such as the aorta and branches of the aorta.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "vasculitis-by-anatomical-site",
        "name": "Vasculitis by anatomical site",
        "url": "https://dantelabs.com/traits/vasculitis-by-anatomical-site"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "nod2",
        "symbol": "NOD2",
        "hgnc": "HGNC:5331",
        "name": "nucleotide binding oligomerization domain containing 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nod2"
      },
      {
        "slug": "was",
        "symbol": "WAS",
        "hgnc": "HGNC:12731",
        "name": "WASP actin nucleation promoting factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/was"
      }
    ]
  }
}