{
  "url": "https://dantelabs.com/traits/internal-hemorrhage",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "internal-hemorrhage",
    "id": "HP:0011029",
    "name": "Internal bleeding",
    "label": "Internal hemorrhage",
    "definition": "The presence of hemorrhage within the body.",
    "synonyms": [
      "Internal haemorrhage"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-blood-circulation",
        "name": "Abnormality of blood circulation",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-circulation"
      },
      {
        "slug": "abnormal-bleeding",
        "name": "Bleeding tendency",
        "url": "https://dantelabs.com/traits/abnormal-bleeding"
      }
    ],
    "narrower": [
      {
        "slug": "gastrointestinal-hemorrhage",
        "name": "Gastrointestinal bleeding",
        "genes": 144,
        "url": "https://dantelabs.com/traits/gastrointestinal-hemorrhage"
      },
      {
        "slug": "intracranial-hemorrhage",
        "name": "Bleeding within the skull",
        "genes": 55,
        "url": "https://dantelabs.com/traits/intracranial-hemorrhage"
      },
      {
        "slug": "joint-hemorrhage",
        "name": "Bleeding within a joint",
        "genes": 18,
        "url": "https://dantelabs.com/traits/joint-hemorrhage"
      },
      {
        "slug": "pulmonary-hemorrhage",
        "name": "Pulmonary hemorrhage",
        "genes": 8,
        "url": "https://dantelabs.com/traits/pulmonary-hemorrhage"
      },
      {
        "slug": "hemorrhage-of-the-eye",
        "name": "Bleeding from the eye",
        "genes": 4,
        "url": "https://dantelabs.com/traits/hemorrhage-of-the-eye"
      },
      {
        "slug": "antepartum-hemorrhage",
        "name": "Antepartum hemorrhage",
        "genes": 1,
        "url": "https://dantelabs.com/traits/antepartum-hemorrhage"
      },
      {
        "slug": "muscle-hemorrhage",
        "name": "Muscle hemorrhage",
        "genes": 1,
        "url": "https://dantelabs.com/traits/muscle-hemorrhage"
      }
    ],
    "genes": [
      {
        "slug": "was",
        "symbol": "WAS",
        "hgnc": "HGNC:12731",
        "name": "WASP actin nucleation promoting factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/was"
      },
      {
        "slug": "col3a1",
        "symbol": "COL3A1",
        "hgnc": "HGNC:2201",
        "name": "collagen type III alpha 1 chain",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col3a1"
      },
      {
        "slug": "aggf1",
        "symbol": "AGGF1",
        "hgnc": "HGNC:24684",
        "name": "angiogenic factor with G-patch and FHA domains 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aggf1"
      },
      {
        "slug": "pik3ca",
        "symbol": "PIK3CA",
        "hgnc": "HGNC:8975",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3ca"
      },
      {
        "slug": "cd46",
        "symbol": "CD46",
        "hgnc": "HGNC:6953",
        "name": "CD46 molecule",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd46"
      },
      {
        "slug": "cfh",
        "symbol": "CFH",
        "hgnc": "HGNC:4883",
        "name": "complement factor H",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfh"
      },
      {
        "slug": "cfi",
        "symbol": "CFI",
        "hgnc": "HGNC:5394",
        "name": "complement factor I",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfi"
      },
      {
        "slug": "hellpar",
        "symbol": "HELLPAR",
        "hgnc": "HGNC:43984",
        "name": "HELLP associated long non-coding RNA",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hellpar"
      },
      {
        "slug": "ifng",
        "symbol": "IFNG",
        "hgnc": "HGNC:5438",
        "name": "interferon gamma",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifng"
      },
      {
        "slug": "tsc1",
        "symbol": "TSC1",
        "hgnc": "HGNC:12362",
        "name": "TSC complex subunit 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tsc1"
      },
      {
        "slug": "tsc2",
        "symbol": "TSC2",
        "hgnc": "HGNC:12363",
        "name": "TSC complex subunit 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tsc2"
      }
    ]
  }
}