{
  "url": "https://dantelabs.com/traits/hypsarrhythmia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hypsarrhythmia",
    "id": "HP:0002521",
    "name": "Hypsarrhythmia",
    "definition": "Hypsarrhythmia is abnormal interictal high amplitude waves and a background of irregular spikes. There is continuous (during wakefulness), high-amplitude (>200 Hz), generalized polymorphic slowing with no organized background and multifocal spikes demonstrated by electroencephalography (EEG).",
    "synonyms": [
      "Hypsarrhythmia by EEG"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "eeg-with-generalized-epileptiform-discharges",
        "name": "EEG with generalized epileptiform discharges",
        "url": "https://dantelabs.com/traits/eeg-with-generalized-epileptiform-discharges"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "alg13",
        "symbol": "ALG13",
        "hgnc": "HGNC:30881",
        "name": "ALG13 UDP-N-acetylglucosaminyltransferase subunit",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/alg13"
      },
      {
        "slug": "alg2",
        "symbol": "ALG2",
        "hgnc": "HGNC:23159",
        "name": "ALG2 alpha-1,3/1,6-mannosyltransferase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/alg2"
      },
      {
        "slug": "arfgef1",
        "symbol": "ARFGEF1",
        "hgnc": "HGNC:15772",
        "name": "ARF guanine nucleotide exchange factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arfgef1"
      },
      {
        "slug": "arv1",
        "symbol": "ARV1",
        "hgnc": "HGNC:29561",
        "name": "ARV1 fatty acid homeostasis modulator",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arv1"
      },
      {
        "slug": "arx",
        "symbol": "ARX",
        "hgnc": "HGNC:18060",
        "name": "aristaless related homeobox",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/arx"
      },
      {
        "slug": "atp6v1a",
        "symbol": "ATP6V1A",
        "hgnc": "HGNC:851",
        "name": "ATPase H+ transporting V1 subunit A",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/atp6v1a"
      },
      {
        "slug": "atp7a",
        "symbol": "ATP7A",
        "hgnc": "HGNC:869",
        "name": "ATPase copper transporting alpha",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp7a"
      },
      {
        "slug": "ccdc88a",
        "symbol": "CCDC88A",
        "hgnc": "HGNC:25523",
        "name": "coiled-coil and HOOK domain protein 88A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc88a"
      },
      {
        "slug": "chaserr",
        "symbol": "CHASERR",
        "hgnc": "HGNC:48626",
        "name": "CHD2 adjacent suppressive regulatory RNA",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chaserr"
      },
      {
        "slug": "dnm1",
        "symbol": "DNM1",
        "hgnc": "HGNC:2972",
        "name": "dynamin 1",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/dnm1"
      },
      {
        "slug": "dpagt1",
        "symbol": "DPAGT1",
        "hgnc": "HGNC:2995",
        "name": "dolichyl-phosphate N-acetylglucosaminephosphotransferase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dpagt1"
      },
      {
        "slug": "eef1a2",
        "symbol": "EEF1A2",
        "hgnc": "HGNC:3192",
        "name": "eukaryotic translation elongation factor 1 alpha 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/eef1a2"
      },
      {
        "slug": "epg5",
        "symbol": "EPG5",
        "hgnc": "HGNC:29331",
        "name": "ectopic P-granules 5 autophagy tethering factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epg5"
      },
      {
        "slug": "ermard",
        "symbol": "ERMARD",
        "hgnc": "HGNC:21056",
        "name": "ER membrane associated RNA degradation",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ermard"
      },
      {
        "slug": "esam",
        "symbol": "ESAM",
        "hgnc": "HGNC:17474",
        "name": "endothelial cell adhesion molecule",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/esam"
      },
      {
        "slug": "gabrb1",
        "symbol": "GABRB1",
        "hgnc": "HGNC:4081",
        "name": "gamma-aminobutyric acid type A receptor subunit beta1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabrb1"
      },
      {
        "slug": "gcsh",
        "symbol": "GCSH",
        "hgnc": "HGNC:4208",
        "name": "glycine cleavage system protein H",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gcsh"
      },
      {
        "slug": "golga2",
        "symbol": "GOLGA2",
        "hgnc": "HGNC:4425",
        "name": "golgin A2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/golga2"
      },
      {
        "slug": "grin2b",
        "symbol": "GRIN2B",
        "hgnc": "HGNC:4586",
        "name": "glutamate ionotropic receptor NMDA type subunit 2B",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/grin2b"
      },
      {
        "slug": "ier3ip1",
        "symbol": "IER3IP1",
        "hgnc": "HGNC:18550",
        "name": "immediate early response 3 interacting protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ier3ip1"
      },
      {
        "slug": "inpp4a",
        "symbol": "INPP4A",
        "hgnc": "HGNC:6074",
        "name": "inositol polyphosphate-4-phosphatase type I A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/inpp4a"
      },
      {
        "slug": "kcnt2",
        "symbol": "KCNT2",
        "hgnc": "HGNC:18866",
        "name": "potassium sodium-activated channel subfamily T member 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnt2"
      },
      {
        "slug": "klhl20",
        "symbol": "KLHL20",
        "hgnc": "HGNC:25056",
        "name": "kelch like family member 20",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/klhl20"
      },
      {
        "slug": "mccc1",
        "symbol": "MCCC1",
        "hgnc": "HGNC:6936",
        "name": "methylcrotonyl-CoA carboxylase subunit 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mccc1"
      },
      {
        "slug": "med17",
        "symbol": "MED17",
        "hgnc": "HGNC:2375",
        "name": "mediator complex subunit 17",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/med17"
      },
      {
        "slug": "mff",
        "symbol": "MFF",
        "hgnc": "HGNC:24858",
        "name": "mitochondrial fission factor",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mff"
      },
      {
        "slug": "msl2",
        "symbol": "MSL2",
        "hgnc": "HGNC:25544",
        "name": "MSL complex subunit 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msl2"
      },
      {
        "slug": "neurod2",
        "symbol": "NEUROD2",
        "hgnc": "HGNC:7763",
        "name": "neuronal differentiation 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/neurod2"
      },
      {
        "slug": "pars2",
        "symbol": "PARS2",
        "hgnc": "HGNC:30563",
        "name": "prolyl-tRNA synthetase 2, mitochondrial",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pars2"
      },
      {
        "slug": "phactr1",
        "symbol": "PHACTR1",
        "hgnc": "HGNC:20990",
        "name": "phosphatase and actin regulator 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/phactr1"
      },
      {
        "slug": "piga",
        "symbol": "PIGA",
        "hgnc": "HGNC:8957",
        "name": "phosphatidylinositol glycan anchor biosynthesis class A",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/piga"
      },
      {
        "slug": "pigw",
        "symbol": "PIGW",
        "hgnc": "HGNC:23213",
        "name": "phosphatidylinositol glycan anchor biosynthesis class W",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigw"
      },
      {
        "slug": "plcb1",
        "symbol": "PLCB1",
        "hgnc": "HGNC:15917",
        "name": "phospholipase C beta 1",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/plcb1"
      },
      {
        "slug": "ptpn23",
        "symbol": "PTPN23",
        "hgnc": "HGNC:14406",
        "name": "protein tyrosine phosphatase non-receptor type 23",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptpn23"
      },
      {
        "slug": "smc1a",
        "symbol": "SMC1A",
        "hgnc": "HGNC:11111",
        "name": "structural maintenance of chromosomes 1A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smc1a"
      },
      {
        "slug": "st3gal3",
        "symbol": "ST3GAL3",
        "hgnc": "HGNC:10866",
        "name": "ST3 beta-galactoside alpha-2,3-sialyltransferase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/st3gal3"
      },
      {
        "slug": "tbl1xr1",
        "symbol": "TBL1XR1",
        "hgnc": "HGNC:29529",
        "name": "TBL1X/Y related 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbl1xr1"
      },
      {
        "slug": "trim8",
        "symbol": "TRIM8",
        "hgnc": "HGNC:15579",
        "name": "tripartite motif containing 8",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trim8"
      },
      {
        "slug": "cdkl5",
        "symbol": "CDKL5",
        "hgnc": "HGNC:11411",
        "name": "cyclin dependent kinase like 5",
        "frequency": "very-frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/cdkl5"
      },
      {
        "slug": "cnpy3",
        "symbol": "CNPY3",
        "hgnc": "HGNC:11968",
        "name": "canopy FGF signaling regulator 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnpy3"
      },
      {
        "slug": "guf1",
        "symbol": "GUF1",
        "hgnc": "HGNC:25799",
        "name": "GTP binding elongation factor GUF1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/guf1"
      },
      {
        "slug": "ntrk2",
        "symbol": "NTRK2",
        "hgnc": "HGNC:8032",
        "name": "neurotrophic receptor tyrosine kinase 2",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/ntrk2"
      },
      {
        "slug": "scn2a",
        "symbol": "SCN2A",
        "hgnc": "HGNC:10588",
        "name": "sodium voltage-gated channel alpha subunit 2",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/scn2a"
      },
      {
        "slug": "sik1",
        "symbol": "SIK1",
        "hgnc": "HGNC:11142",
        "name": "salt inducible kinase 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/sik1"
      },
      {
        "slug": "slc35a2",
        "symbol": "SLC35A2",
        "hgnc": "HGNC:11022",
        "name": "solute carrier family 35 member A2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc35a2"
      },
      {
        "slug": "spout1",
        "symbol": "SPOUT1",
        "hgnc": "HGNC:26933",
        "name": "SPOUT domain containing methyltransferase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spout1"
      },
      {
        "slug": "sptan1",
        "symbol": "SPTAN1",
        "hgnc": "HGNC:11273",
        "name": "spectrin alpha, non-erythrocytic 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sptan1"
      },
      {
        "slug": "wdr45",
        "symbol": "WDR45",
        "hgnc": "HGNC:28912",
        "name": "WD repeat domain 45",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr45"
      },
      {
        "slug": "znhit3",
        "symbol": "ZNHIT3",
        "hgnc": "HGNC:12309",
        "name": "zinc finger HIT-type containing 3",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/znhit3"
      },
      {
        "slug": "alg14",
        "symbol": "ALG14",
        "hgnc": "HGNC:28287",
        "name": "ALG14 UDP-N-acetylglucosaminyltransferase subunit",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alg14"
      },
      {
        "slug": "asns",
        "symbol": "ASNS",
        "hgnc": "HGNC:753",
        "name": "asparagine synthetase (glutamine-hydrolyzing)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asns"
      },
      {
        "slug": "atad1",
        "symbol": "ATAD1",
        "hgnc": "HGNC:25903",
        "name": "ATPase family AAA domain containing 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atad1"
      },
      {
        "slug": "atp6v0a1",
        "symbol": "ATP6V0A1",
        "hgnc": "HGNC:865",
        "name": "ATPase H+ transporting V0 subunit a1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v0a1"
      },
      {
        "slug": "cacna1e",
        "symbol": "CACNA1E",
        "hgnc": "HGNC:1392",
        "name": "calcium voltage-gated channel subunit alpha1 E",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cacna1e"
      },
      {
        "slug": "cask",
        "symbol": "CASK",
        "hgnc": "HGNC:1497",
        "name": "calcium/calmodulin dependent serine protein kinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cask"
      },
      {
        "slug": "celf2",
        "symbol": "CELF2",
        "hgnc": "HGNC:2550",
        "name": "CUGBP Elav-like family member 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/celf2"
      },
      {
        "slug": "cox4i1",
        "symbol": "COX4I1",
        "hgnc": "HGNC:2265",
        "name": "cytochrome c oxidase subunit 4I1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cox4i1"
      },
      {
        "slug": "cul3",
        "symbol": "CUL3",
        "hgnc": "HGNC:2553",
        "name": "cullin 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cul3"
      },
      {
        "slug": "cyfip2",
        "symbol": "CYFIP2",
        "hgnc": "HGNC:13760",
        "name": "cytoplasmic FMR1 interacting protein 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cyfip2"
      },
      {
        "slug": "d2hgdh",
        "symbol": "D2HGDH",
        "hgnc": "HGNC:28358",
        "name": "D-2-hydroxyglutarate dehydrogenase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/d2hgdh"
      },
      {
        "slug": "dmxl2",
        "symbol": "DMXL2",
        "hgnc": "HGNC:2938",
        "name": "Dmx like 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dmxl2"
      },
      {
        "slug": "dock7",
        "symbol": "DOCK7",
        "hgnc": "HGNC:19190",
        "name": "dedicator of cytokinesis 7",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dock7"
      },
      {
        "slug": "epm2a",
        "symbol": "EPM2A",
        "hgnc": "HGNC:3413",
        "name": "EPM2A glucan phosphatase, laforin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epm2a"
      },
      {
        "slug": "exoc8",
        "symbol": "EXOC8",
        "hgnc": "HGNC:24659",
        "name": "exocyst complex component 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/exoc8"
      },
      {
        "slug": "fgf12",
        "symbol": "FGF12",
        "hgnc": "HGNC:3668",
        "name": "fibroblast growth factor 12",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fgf12"
      },
      {
        "slug": "fgf13",
        "symbol": "FGF13",
        "hgnc": "HGNC:3670",
        "name": "fibroblast growth factor 13",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf13"
      },
      {
        "slug": "gabbr2",
        "symbol": "GABBR2",
        "hgnc": "HGNC:4507",
        "name": "gamma-aminobutyric acid type B receptor subunit 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gabbr2"
      },
      {
        "slug": "gnao1",
        "symbol": "GNAO1",
        "hgnc": "HGNC:4389",
        "name": "G protein subunit alpha o1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gnao1"
      },
      {
        "slug": "grin1",
        "symbol": "GRIN1",
        "hgnc": "HGNC:4584",
        "name": "glutamate ionotropic receptor NMDA type subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grin1"
      },
      {
        "slug": "grin2d",
        "symbol": "GRIN2D",
        "hgnc": "HGNC:4588",
        "name": "glutamate ionotropic receptor NMDA type subunit 2D",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/grin2d"
      },
      {
        "slug": "grm7",
        "symbol": "GRM7",
        "hgnc": "HGNC:4599",
        "name": "glutamate metabotropic receptor 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grm7"
      },
      {
        "slug": "hibch",
        "symbol": "HIBCH",
        "hgnc": "HGNC:4908",
        "name": "3-hydroxyisobutyryl-CoA hydrolase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hibch"
      },
      {
        "slug": "kcna1",
        "symbol": "KCNA1",
        "hgnc": "HGNC:6218",
        "name": "potassium voltage-gated channel subfamily A member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcna1"
      },
      {
        "slug": "kcnb1",
        "symbol": "KCNB1",
        "hgnc": "HGNC:6231",
        "name": "potassium voltage-gated channel subfamily B member 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnb1"
      },
      {
        "slug": "lgi1",
        "symbol": "LGI1",
        "hgnc": "HGNC:6572",
        "name": "leucine rich glioma inactivated 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lgi1"
      },
      {
        "slug": "mpdu1",
        "symbol": "MPDU1",
        "hgnc": "HGNC:7207",
        "name": "mannose-P-dolichol utilization defect 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mpdu1"
      },
      {
        "slug": "nacc1",
        "symbol": "NACC1",
        "hgnc": "HGNC:20967",
        "name": "nucleus accumbens associated 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nacc1"
      },
      {
        "slug": "ndufaf8",
        "symbol": "NDUFAF8",
        "hgnc": "HGNC:33551",
        "name": "NADH:ubiquinone oxidoreductase complex assembly factor 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndufaf8"
      },
      {
        "slug": "nhlrc1",
        "symbol": "NHLRC1",
        "hgnc": "HGNC:21576",
        "name": "NHL repeat containing E3 ubiquitin protein ligase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nhlrc1"
      },
      {
        "slug": "otud7a",
        "symbol": "OTUD7A",
        "hgnc": "HGNC:20718",
        "name": "OTU deubiquitinase 7A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otud7a"
      },
      {
        "slug": "pcdh12",
        "symbol": "PCDH12",
        "hgnc": "HGNC:8657",
        "name": "protocadherin 12",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pcdh12"
      },
      {
        "slug": "pigp",
        "symbol": "PIGP",
        "hgnc": "HGNC:3046",
        "name": "phosphatidylinositol glycan anchor biosynthesis class P",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pigp"
      },
      {
        "slug": "pigq",
        "symbol": "PIGQ",
        "hgnc": "HGNC:14135",
        "name": "phosphatidylinositol glycan anchor biosynthesis class Q",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigq"
      },
      {
        "slug": "plaa",
        "symbol": "PLAA",
        "hgnc": "HGNC:9043",
        "name": "phospholipase A2 activating protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plaa"
      },
      {
        "slug": "pnkp",
        "symbol": "PNKP",
        "hgnc": "HGNC:9154",
        "name": "polynucleotide kinase 3'-phosphatase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnkp"
      },
      {
        "slug": "ppp3ca",
        "symbol": "PPP3CA",
        "hgnc": "HGNC:9314",
        "name": "protein phosphatase 3 catalytic subunit alpha",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ppp3ca"
      },
      {
        "slug": "rhobtb2",
        "symbol": "RHOBTB2",
        "hgnc": "HGNC:18756",
        "name": "Rho related BTB domain containing 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rhobtb2"
      },
      {
        "slug": "rusc2",
        "symbol": "RUSC2",
        "hgnc": "HGNC:23625",
        "name": "RUN and SH3 domain containing 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rusc2"
      },
      {
        "slug": "scn1b",
        "symbol": "SCN1B",
        "hgnc": "HGNC:10586",
        "name": "sodium voltage-gated channel beta subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn1b"
      },
      {
        "slug": "slc1a2",
        "symbol": "SLC1A2",
        "hgnc": "HGNC:10940",
        "name": "solute carrier family 1 member 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc1a2"
      },
      {
        "slug": "slc25a22",
        "symbol": "SLC25A22",
        "hgnc": "HGNC:19954",
        "name": "solute carrier family 25 member 22",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc25a22"
      },
      {
        "slug": "slc32a1",
        "symbol": "SLC32A1",
        "hgnc": "HGNC:11018",
        "name": "solute carrier family 32 member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc32a1"
      },
      {
        "slug": "synj1",
        "symbol": "SYNJ1",
        "hgnc": "HGNC:11503",
        "name": "synaptojanin 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/synj1"
      },
      {
        "slug": "tgfb1",
        "symbol": "TGFB1",
        "hgnc": "HGNC:11766",
        "name": "transforming growth factor beta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfb1"
      },
      {
        "slug": "timm50",
        "symbol": "TIMM50",
        "hgnc": "HGNC:23656",
        "name": "translocase of inner mitochondrial membrane 50",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/timm50"
      },
      {
        "slug": "tra2b",
        "symbol": "TRA2B",
        "hgnc": "HGNC:10781",
        "name": "transformer 2 beta homolog",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tra2b"
      },
      {
        "slug": "trappc12",
        "symbol": "TRAPPC12",
        "hgnc": "HGNC:24284",
        "name": "trafficking protein particle complex subunit 12",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trappc12"
      },
      {
        "slug": "tubb2a",
        "symbol": "TUBB2A",
        "hgnc": "HGNC:12412",
        "name": "tubulin beta 2A class IIa",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tubb2a"
      },
      {
        "slug": "unc13a",
        "symbol": "UNC13A",
        "hgnc": "HGNC:23150",
        "name": "unc-13 homolog A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/unc13a"
      },
      {
        "slug": "aars1",
        "symbol": "AARS1",
        "hgnc": "HGNC:20",
        "name": "alanyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aars1"
      },
      {
        "slug": "abcc8",
        "symbol": "ABCC8",
        "hgnc": "HGNC:59",
        "name": "ATP binding cassette subfamily C member 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcc8"
      },
      {
        "slug": "actl6b",
        "symbol": "ACTL6B",
        "hgnc": "HGNC:160",
        "name": "actin like 6B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actl6b"
      },
      {
        "slug": "afg2a",
        "symbol": "AFG2A",
        "hgnc": "HGNC:18119",
        "name": "AAA ATPase AFG2A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/afg2a"
      },
      {
        "slug": "aldh7a1",
        "symbol": "ALDH7A1",
        "hgnc": "HGNC:877",
        "name": "aldehyde dehydrogenase 7 family member A1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh7a1"
      },
      {
        "slug": "ap3b2",
        "symbol": "AP3B2",
        "hgnc": "HGNC:567",
        "name": "adaptor related protein complex 3 subunit beta 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ap3b2"
      },
      {
        "slug": "apc2",
        "symbol": "APC2",
        "hgnc": "HGNC:24036",
        "name": "APC regulator of Wnt signaling pathway 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apc2"
      },
      {
        "slug": "aspa",
        "symbol": "ASPA",
        "hgnc": "HGNC:756",
        "name": "aspartoacylase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aspa"
      },
      {
        "slug": "atn1",
        "symbol": "ATN1",
        "hgnc": "HGNC:3033",
        "name": "atrophin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atn1"
      },
      {
        "slug": "atp1a2",
        "symbol": "ATP1A2",
        "hgnc": "HGNC:800",
        "name": "ATPase Na+/K+ transporting subunit alpha 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp1a2"
      },
      {
        "slug": "atp1a3",
        "symbol": "ATP1A3",
        "hgnc": "HGNC:801",
        "name": "ATPase Na+/K+ transporting subunit alpha 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp1a3"
      },
      {
        "slug": "cacna1a",
        "symbol": "CACNA1A",
        "hgnc": "HGNC:1388",
        "name": "calcium voltage-gated channel subunit alpha1 A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1a"
      },
      {
        "slug": "cacna1b",
        "symbol": "CACNA1B",
        "hgnc": "HGNC:1389",
        "name": "calcium voltage-gated channel subunit alpha1 B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1b"
      },
      {
        "slug": "cacna2d1",
        "symbol": "CACNA2D1",
        "hgnc": "HGNC:1399",
        "name": "calcium voltage-gated channel auxiliary subunit alpha2delta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna2d1"
      },
      {
        "slug": "camsap1",
        "symbol": "CAMSAP1",
        "hgnc": "HGNC:19946",
        "name": "calmodulin regulated spectrin associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/camsap1"
      },
      {
        "slug": "caprin1",
        "symbol": "CAPRIN1",
        "hgnc": "HGNC:6743",
        "name": "cell cycle associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/caprin1"
      },
      {
        "slug": "cdk19",
        "symbol": "CDK19",
        "hgnc": "HGNC:19338",
        "name": "cyclin dependent kinase 19",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdk19"
      },
      {
        "slug": "cltc",
        "symbol": "CLTC",
        "hgnc": "HGNC:2092",
        "name": "clathrin heavy chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cltc"
      },
      {
        "slug": "cnksr2",
        "symbol": "CNKSR2",
        "hgnc": "HGNC:19701",
        "name": "connector enhancer of kinase suppressor of Ras 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnksr2"
      },
      {
        "slug": "ctnna2",
        "symbol": "CTNNA2",
        "hgnc": "HGNC:2510",
        "name": "catenin alpha 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctnna2"
      },
      {
        "slug": "cux2",
        "symbol": "CUX2",
        "hgnc": "HGNC:19347",
        "name": "cut like homeobox 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cux2"
      },
      {
        "slug": "dalrd3",
        "symbol": "DALRD3",
        "hgnc": "HGNC:25536",
        "name": "DALR anticodon binding domain containing 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dalrd3"
      },
      {
        "slug": "dcx",
        "symbol": "DCX",
        "hgnc": "HGNC:2714",
        "name": "doublecortin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dcx"
      },
      {
        "slug": "depdc5",
        "symbol": "DEPDC5",
        "hgnc": "HGNC:18423",
        "name": "DEP domain containing 5, GATOR1 subcomplex subunit",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/depdc5"
      },
      {
        "slug": "dhdds",
        "symbol": "DHDDS",
        "hgnc": "HGNC:20603",
        "name": "dehydrodolichyl diphosphate synthase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhdds"
      },
      {
        "slug": "dolk",
        "symbol": "DOLK",
        "hgnc": "HGNC:23406",
        "name": "dolichol kinase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dolk"
      },
      {
        "slug": "fbxo28",
        "symbol": "FBXO28",
        "hgnc": "HGNC:29046",
        "name": "F-box protein 28",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxo28"
      },
      {
        "slug": "fh",
        "symbol": "FH",
        "hgnc": "HGNC:3700",
        "name": "fumarate hydratase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fh"
      },
      {
        "slug": "foxg1",
        "symbol": "FOXG1",
        "hgnc": "HGNC:3811",
        "name": "forkhead box G1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxg1"
      },
      {
        "slug": "fzr1",
        "symbol": "FZR1",
        "hgnc": "HGNC:24824",
        "name": "fizzy and cell division cycle 20 related 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fzr1"
      },
      {
        "slug": "gabra2",
        "symbol": "GABRA2",
        "hgnc": "HGNC:4076",
        "name": "gamma-aminobutyric acid type A receptor subunit alpha2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabra2"
      },
      {
        "slug": "gabra5",
        "symbol": "GABRA5",
        "hgnc": "HGNC:4079",
        "name": "gamma-aminobutyric acid type A receptor subunit alpha5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabra5"
      },
      {
        "slug": "gabrb2",
        "symbol": "GABRB2",
        "hgnc": "HGNC:4082",
        "name": "gamma-aminobutyric acid type A receptor subunit beta2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabrb2"
      },
      {
        "slug": "gabrb3",
        "symbol": "GABRB3",
        "hgnc": "HGNC:4083",
        "name": "gamma-aminobutyric acid type A receptor subunit beta3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabrb3"
      },
      {
        "slug": "gabrg2",
        "symbol": "GABRG2",
        "hgnc": "HGNC:4087",
        "name": "gamma-aminobutyric acid type A receptor subunit gamma2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabrg2"
      },
      {
        "slug": "gad1",
        "symbol": "GAD1",
        "hgnc": "HGNC:4092",
        "name": "glutamate decarboxylase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gad1"
      },
      {
        "slug": "gfm2",
        "symbol": "GFM2",
        "hgnc": "HGNC:29682",
        "name": "GTP dependent ribosome recycling factor mitochondrial 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gfm2"
      },
      {
        "slug": "gnb1",
        "symbol": "GNB1",
        "hgnc": "HGNC:4396",
        "name": "G protein subunit beta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnb1"
      },
      {
        "slug": "gnb5",
        "symbol": "GNB5",
        "hgnc": "HGNC:4401",
        "name": "G protein subunit beta 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnb5"
      },
      {
        "slug": "hcfc1",
        "symbol": "HCFC1",
        "hgnc": "HGNC:4839",
        "name": "host cell factor C1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hcfc1"
      },
      {
        "slug": "hcn1",
        "symbol": "HCN1",
        "hgnc": "HGNC:4845",
        "name": "hyperpolarization activated cyclic nucleotide gated potassium channel 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hcn1"
      },
      {
        "slug": "hid1",
        "symbol": "HID1",
        "hgnc": "HGNC:15736",
        "name": "HID1 domain containing",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hid1"
      },
      {
        "slug": "hmgcl",
        "symbol": "HMGCL",
        "hgnc": "HGNC:5005",
        "name": "3-hydroxy-3-methylglutaryl-CoA lyase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hmgcl"
      },
      {
        "slug": "iars2",
        "symbol": "IARS2",
        "hgnc": "HGNC:29685",
        "name": "isoleucyl-tRNA synthetase 2, mitochondrial",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/iars2"
      },
      {
        "slug": "kcna2",
        "symbol": "KCNA2",
        "hgnc": "HGNC:6220",
        "name": "potassium voltage-gated channel subfamily A member 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcna2"
      },
      {
        "slug": "kcnc2",
        "symbol": "KCNC2",
        "hgnc": "HGNC:6234",
        "name": "potassium voltage-gated channel subfamily C member 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnc2"
      },
      {
        "slug": "kcnh5",
        "symbol": "KCNH5",
        "hgnc": "HGNC:6254",
        "name": "potassium voltage-gated channel subfamily H member 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnh5"
      },
      {
        "slug": "kcnj11",
        "symbol": "KCNJ11",
        "hgnc": "HGNC:6257",
        "name": "potassium inwardly rectifying channel subfamily J member 11",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnj11"
      },
      {
        "slug": "kcnq2",
        "symbol": "KCNQ2",
        "hgnc": "HGNC:6296",
        "name": "potassium voltage-gated channel subfamily Q member 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnq2"
      },
      {
        "slug": "kcnt1",
        "symbol": "KCNT1",
        "hgnc": "HGNC:18865",
        "name": "potassium sodium-activated channel subfamily T member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnt1"
      },
      {
        "slug": "lonp1",
        "symbol": "LONP1",
        "hgnc": "HGNC:9479",
        "name": "lon peptidase 1, mitochondrial",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lonp1"
      },
      {
        "slug": "mdga2",
        "symbol": "MDGA2",
        "hgnc": "HGNC:19835",
        "name": "MAM domain containing glycosylphosphatidylinositol anchor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdga2"
      },
      {
        "slug": "mgat2",
        "symbol": "MGAT2",
        "hgnc": "HGNC:7045",
        "name": "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mgat2"
      },
      {
        "slug": "mt-tl1",
        "symbol": "MT-TL1",
        "hgnc": "HGNC:7490",
        "name": "mitochondrially encoded tRNA-Leu (UUA/G) 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-tl1"
      },
      {
        "slug": "nars2",
        "symbol": "NARS2",
        "hgnc": "HGNC:26274",
        "name": "asparaginyl-tRNA synthetase 2, mitochondrial",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nars2"
      },
      {
        "slug": "naxd",
        "symbol": "NAXD",
        "hgnc": "HGNC:25576",
        "name": "NAD(P)HX dehydratase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/naxd"
      },
      {
        "slug": "necap1",
        "symbol": "NECAP1",
        "hgnc": "HGNC:24539",
        "name": "NECAP endocytosis associated 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/necap1"
      },
      {
        "slug": "nedd4l",
        "symbol": "NEDD4L",
        "hgnc": "HGNC:7728",
        "name": "NEDD4 like E3 ubiquitin protein ligase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nedd4l"
      },
      {
        "slug": "nexmif",
        "symbol": "NEXMIF",
        "hgnc": "HGNC:29433",
        "name": "neurite extension and migration factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nexmif"
      },
      {
        "slug": "nus1",
        "symbol": "NUS1",
        "hgnc": "HGNC:21042",
        "name": "NUS1 dehydrodolichyl diphosphate synthase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nus1"
      },
      {
        "slug": "pacs2",
        "symbol": "PACS2",
        "hgnc": "HGNC:23794",
        "name": "phosphofurin acidic cluster sorting protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pacs2"
      },
      {
        "slug": "pafah1b1",
        "symbol": "PAFAH1B1",
        "hgnc": "HGNC:8574",
        "name": "platelet activating factor acetylhydrolase 1b regulatory subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pafah1b1"
      },
      {
        "slug": "pdha1",
        "symbol": "PDHA1",
        "hgnc": "HGNC:8806",
        "name": "pyruvate dehydrogenase E1 subunit alpha 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pdha1"
      },
      {
        "slug": "pi4k2a",
        "symbol": "PI4K2A",
        "hgnc": "HGNC:30031",
        "name": "phosphatidylinositol 4-kinase type 2 alpha",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pi4k2a"
      },
      {
        "slug": "plpbp",
        "symbol": "PLPBP",
        "hgnc": "HGNC:9457",
        "name": "pyridoxal phosphate binding protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plpbp"
      },
      {
        "slug": "ppfibp1",
        "symbol": "PPFIBP1",
        "hgnc": "HGNC:9249",
        "name": "PPFIB scaffold protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppfibp1"
      },
      {
        "slug": "pts",
        "symbol": "PTS",
        "hgnc": "HGNC:9689",
        "name": "6-pyruvoyltetrahydropterin synthase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pts"
      },
      {
        "slug": "satb1",
        "symbol": "SATB1",
        "hgnc": "HGNC:10541",
        "name": "SATB homeobox 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/satb1"
      },
      {
        "slug": "scn1a",
        "symbol": "SCN1A",
        "hgnc": "HGNC:10585",
        "name": "sodium voltage-gated channel alpha subunit 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/scn1a"
      },
      {
        "slug": "scn3a",
        "symbol": "SCN3A",
        "hgnc": "HGNC:10590",
        "name": "sodium voltage-gated channel alpha subunit 3",
        "frequency": "occasional",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/scn3a"
      },
      {
        "slug": "scn8a",
        "symbol": "SCN8A",
        "hgnc": "HGNC:10596",
        "name": "sodium voltage-gated channel alpha subunit 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn8a"
      },
      {
        "slug": "slc12a5",
        "symbol": "SLC12A5",
        "hgnc": "HGNC:13818",
        "name": "solute carrier family 12 member 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc12a5"
      },
      {
        "slug": "slc13a5",
        "symbol": "SLC13A5",
        "hgnc": "HGNC:23089",
        "name": "solute carrier family 13 member 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc13a5"
      },
      {
        "slug": "slc1a4",
        "symbol": "SLC1A4",
        "hgnc": "HGNC:10942",
        "name": "solute carrier family 1 member 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc1a4"
      },
      {
        "slug": "slc38a3",
        "symbol": "SLC38A3",
        "hgnc": "HGNC:18044",
        "name": "solute carrier family 38 member 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc38a3"
      },
      {
        "slug": "slc39a8",
        "symbol": "SLC39A8",
        "hgnc": "HGNC:20862",
        "name": "solute carrier family 39 member 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc39a8"
      },
      {
        "slug": "stxbp1",
        "symbol": "STXBP1",
        "hgnc": "HGNC:11444",
        "name": "syntaxin binding protein 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/stxbp1"
      },
      {
        "slug": "syngap1",
        "symbol": "SYNGAP1",
        "hgnc": "HGNC:11497",
        "name": "synaptic Ras GTPase activating protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/syngap1"
      },
      {
        "slug": "szt2",
        "symbol": "SZT2",
        "hgnc": "HGNC:29040",
        "name": "SZT2 subunit of KICSTOR complex",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/szt2"
      },
      {
        "slug": "tbc1d24",
        "symbol": "TBC1D24",
        "hgnc": "HGNC:29203",
        "name": "TBC1 domain family member 24",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d24"
      },
      {
        "slug": "trak1",
        "symbol": "TRAK1",
        "hgnc": "HGNC:29947",
        "name": "trafficking kinesin protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trak1"
      },
      {
        "slug": "uba5",
        "symbol": "UBA5",
        "hgnc": "HGNC:23230",
        "name": "ubiquitin like modifier activating enzyme 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/uba5"
      },
      {
        "slug": "ufc1",
        "symbol": "UFC1",
        "hgnc": "HGNC:26941",
        "name": "ubiquitin-fold modifier conjugating enzyme 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ufc1"
      },
      {
        "slug": "ufsp2",
        "symbol": "UFSP2",
        "hgnc": "HGNC:25640",
        "name": "UFM1 specific peptidase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ufsp2"
      },
      {
        "slug": "upb1",
        "symbol": "UPB1",
        "hgnc": "HGNC:16297",
        "name": "beta-ureidopropionase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/upb1"
      },
      {
        "slug": "ywhag",
        "symbol": "YWHAG",
        "hgnc": "HGNC:12852",
        "name": "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ywhag"
      },
      {
        "slug": "znf526",
        "symbol": "ZNF526",
        "hgnc": "HGNC:29415",
        "name": "zinc finger protein 526",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf526"
      },
      {
        "slug": "nprl2",
        "symbol": "NPRL2",
        "hgnc": "HGNC:24969",
        "name": "NPR2 like, GATOR1 complex subunit",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nprl2"
      },
      {
        "slug": "nprl3",
        "symbol": "NPRL3",
        "hgnc": "HGNC:14124",
        "name": "NPR3 like, GATOR1 complex subunit",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nprl3"
      },
      {
        "slug": "setbp1",
        "symbol": "SETBP1",
        "hgnc": "HGNC:15573",
        "name": "SET binding protein 1",
        "frequency": "very-rare",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/setbp1"
      },
      {
        "slug": "sptbn1",
        "symbol": "SPTBN1",
        "hgnc": "HGNC:11275",
        "name": "spectrin beta, non-erythrocytic 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sptbn1"
      },
      {
        "slug": "aimp2",
        "symbol": "AIMP2",
        "hgnc": "HGNC:20609",
        "name": "aminoacyl tRNA synthetase complex interacting multifunctional protein 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aimp2"
      },
      {
        "slug": "alg3",
        "symbol": "ALG3",
        "hgnc": "HGNC:23056",
        "name": "ALG3 alpha-1,3- mannosyltransferase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alg3"
      },
      {
        "slug": "arfgef2",
        "symbol": "ARFGEF2",
        "hgnc": "HGNC:15853",
        "name": "ARF guanine nucleotide exchange factor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arfgef2"
      },
      {
        "slug": "glyctk",
        "symbol": "GLYCTK",
        "hgnc": "HGNC:24247",
        "name": "glycerate kinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/glyctk"
      },
      {
        "slug": "mdh1",
        "symbol": "MDH1",
        "hgnc": "HGNC:6970",
        "name": "malate dehydrogenase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdh1"
      },
      {
        "slug": "nf1",
        "symbol": "NF1",
        "hgnc": "HGNC:7765",
        "name": "neurofibromin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nf1"
      },
      {
        "slug": "phgdh",
        "symbol": "PHGDH",
        "hgnc": "HGNC:8923",
        "name": "phosphoglycerate dehydrogenase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phgdh"
      },
      {
        "slug": "rogdi",
        "symbol": "ROGDI",
        "hgnc": "HGNC:29478",
        "name": "rogdi atypical leucine zipper",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rogdi"
      },
      {
        "slug": "ugdh",
        "symbol": "UGDH",
        "hgnc": "HGNC:12525",
        "name": "UDP-glucose 6-dehydrogenase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ugdh"
      }
    ]
  }
}