{
  "url": "https://dantelabs.com/traits/hyperhistidinemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperhistidinemia",
    "id": "HP:0010906",
    "name": "High blood histidine level",
    "label": "Hyperhistidinemia",
    "definition": "The concentration of histidine in the blood circulation is above the upper limit of normal.",
    "synonyms": [
      "Elevated histidine concentration",
      "Elevated histidine level",
      "Elevated histidine level in blood",
      "Increased histidine concentration",
      "Increased histidine level",
      "Increased histidine level in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-histidine-concentration",
        "name": "Abnormal circulating histidine concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-histidine-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "hal",
        "symbol": "HAL",
        "hgnc": "HGNC:4806",
        "name": "histidine ammonia-lyase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hal"
      }
    ]
  }
}