{
  "url": "https://dantelabs.com/tr/genes/zmynd8",
  "gene": {
    "slug": "zmynd8",
    "symbol": "ZMYND8",
    "name": "zinc finger MYND-type containing 8",
    "hgnc": "HGNC:9397",
    "summary": null,
    "location": "20q13.12",
    "locusType": "gene with protein product",
    "aliases": [
      "RACK7",
      "KIAA1125"
    ],
    "previousSymbols": [
      "PRKCBP1"
    ],
    "ensemblId": "ENSG00000101040",
    "entrezId": 23613,
    "omim": [
      "615713"
    ],
    "uniprot": [
      "Q9ULU4"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "20",
      "start": 47209214,
      "end": 47356699,
      "strand": "-",
      "ensemblTranscript": "ENST00000471951.7",
      "refseqTranscript": "NM_001281775.3",
      "ensemblProtein": "ENSP00000420095.2",
      "refseqProtein": "NP_001268704.1",
      "exons": [
        {
          "start": 47209214,
          "end": 47210897
        },
        {
          "start": 47212642,
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        },
        {
          "start": 47220258,
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        },
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        },
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        },
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        },
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        },
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        },
        {
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        },
        {
          "start": 47287229,
          "end": 47287284
        },
        {
          "start": 47290187,
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        },
        {
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        },
        {
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        },
        {
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        },
        {
          "start": 47310056,
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        },
        {
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          "end": 47347926
        },
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          "end": 47356699
        }
      ],
      "cds": {
        "start": 47210761,
        "end": 47356670
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "20",
      "start": 45837859,
      "end": 45985567,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 46782957,
      "end": 47782956,
      "genes": [
        {
          "symbol": "EYA2",
          "ensemblId": "ENSG00000064655",
          "biotype": "protein_coding",
          "start": 46894587,
          "end": 47188844,
          "strand": "+",
          "slug": "eya2"
        },
        {
          "symbol": "NCOA3",
          "ensemblId": "ENSG00000124151",
          "biotype": "protein_coding",
          "start": 47501849,
          "end": 47656877,
          "strand": "+",
          "slug": "ncoa3"
        },
        {
          "symbol": "SULF2",
          "ensemblId": "ENSG00000196562",
          "biotype": "protein_coding",
          "start": 47656197,
          "end": 47786842,
          "strand": "-",
          "slug": "sulf2"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "syndromic-complex-neurodevelopmental-disorder",
        "name": "Sendromik Kompleks Nörogelişimsel Bozukluk",
        "diseases": [
          {
            "mondoId": "MONDO:0800439",
            "name": "Sendromik Kompleks Nörogelişimsel Bozukluk",
            "genes": 23,
            "inheritance": null,
            "description": "Beyin dışındaki özelliklerle birlikte gelişimsel gecikme paylaşan, her biri tek bir gendeki değişikliklerden kaynaklanan hastalıklar grubu. ANKRD17, ASH1L ve MYT1L gibi bazı genlerdeki değişiklikler, genellikle de novo olarak, bir kopya değiştiğinde hastalığa yol açar; AFG2A ile ilişkili hastalık ise her iki kopyadaki değişiklikleri gerektirir.",
            "management": "Gelişimsel, eğitimsel ve terapi desteği; ilgili gene göre nöbetler, büyüme, görme, işitme ve diğer organ özellikleri açısından değerlendirme. Genetik danışmanlık gene bağlıdır: de novo dominant değişikliklerde ebeveyn testi, çekinik formlarda ise taşıyıcılık testi.",
            "evidence": {
              "gencc": [
                "ClinGen"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/tr/conditions/syndromic-complex-neurodevelopmental-disorder"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [
      {
        "slug": "afg2a",
        "symbol": "AFG2A",
        "name": "AAA ATPase AFG2A",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/afg2a"
      },
      {
        "slug": "ankrd17",
        "symbol": "ANKRD17",
        "name": "ankyrin repeat domain 17",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/ankrd17"
      },
      {
        "slug": "ap1s2",
        "symbol": "AP1S2",
        "name": "adaptor related protein complex 1 subunit sigma 2",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/ap1s2"
      },
      {
        "slug": "ash1l",
        "symbol": "ASH1L",
        "name": "ASH1 like histone lysine methyltransferase",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/ash1l"
      },
      {
        "slug": "brpf1",
        "symbol": "BRPF1",
        "name": "bromodomain and PHD finger containing 1",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/brpf1"
      },
      {
        "slug": "myt1l",
        "symbol": "MYT1L",
        "name": "myelin transcription factor 1 like",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/myt1l"
      },
      {
        "slug": "nfib",
        "symbol": "NFIB",
        "name": "nuclear factor I B",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/nfib"
      },
      {
        "slug": "pan2",
        "symbol": "PAN2",
        "name": "poly(A) specific ribonuclease subunit PAN2",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/pan2"
      },
      {
        "slug": "qrich1",
        "symbol": "QRICH1",
        "name": "glutamine rich 1",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/qrich1"
      },
      {
        "slug": "rnu4-2",
        "symbol": "RNU4-2",
        "name": "RNA, U4 small nuclear 2",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/rnu4-2"
      },
      {
        "slug": "setd5",
        "symbol": "SETD5",
        "name": "SET domain containing 5",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/setd5"
      },
      {
        "slug": "tbck",
        "symbol": "TBCK",
        "name": "TBC1 domain containing kinase",
        "shared": 1,
        "url": "https://dantelabs.com/tr/genes/tbck"
      }
    ],
    "sources": {
      "bundleId": "2026.10.19-9814e911",
      "panel": "2026-10-19",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}