{
  "url": "https://dantelabs.com/tr/genes/sash1",
  "gene": {
    "slug": "sash1",
    "symbol": "SASH1",
    "name": "SAM and SH3 domain containing 1",
    "hgnc": "HGNC:19182",
    "summary": null,
    "location": "6q24.3-q25.1",
    "locusType": "gene with protein product",
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    "uniprot": [
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    "model": {
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      "release": "v1.5",
      "chrom": "6",
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      "strand": "+",
      "ensemblTranscript": "ENST00000367467.8",
      "refseqTranscript": "NM_015278.5",
      "ensemblProtein": "ENSP00000356437.3",
      "refseqProtein": "NP_056093.3",
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    "grch37": {
      "build": "GRCh37",
      "release": "87",
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    "neighbourhood": {
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        {
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          "ensemblId": "ENSG00000111962",
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          "strand": "+",
          "slug": "ust"
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      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "alopecia-of-scalp",
        "name": "Absence of scalp hair",
        "systems": [
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          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/alopecia-of-scalp"
      },
      {
        "slug": "dry-skin",
        "name": "Dry skin",
        "systems": [
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/dry-skin"
      },
      {
        "slug": "spontaneous-tooth-loss",
        "name": "Early tooth loss",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/spontaneous-tooth-loss"
      },
      {
        "slug": "freckling",
        "name": "Freckling",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/freckling"
      },
      {
        "slug": "alopecia",
        "name": "Hair loss",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/alopecia"
      },
      {
        "slug": "hypermelanotic-macule",
        "name": "Hyperpigmented skin patches",
        "systems": [
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        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hypermelanotic-macule"
      },
      {
        "slug": "hyperpigmented-hypopigmented-macules",
        "name": "Hyperpigmented/hypopigmented macules",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/hyperpigmented-hypopigmented-macules"
      },
      {
        "slug": "hypomelanotic-macule",
        "name": "Hypomelanotic macule",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypomelanotic-macule"
      },
      {
        "slug": "multinodular-goiter",
        "name": "Multinodular goiter",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/multinodular-goiter"
      },
      {
        "slug": "nail-dystrophy",
        "name": "Poor nail formation",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/nail-dystrophy"
      },
      {
        "slug": "scaling-skin",
        "name": "Scaling skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/scaling-skin"
      },
      {
        "slug": "conjunctival-telangiectasia",
        "name": "Small dilated blood vessels near membrane covering front of eye and eyelids",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-eye",
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/conjunctival-telangiectasia"
      },
      {
        "slug": "squamous-cell-carcinoma",
        "name": "Squamous cell carcinoma",
        "systems": [
          "abnormality-of-the-integument",
          "neoplasm"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/squamous-cell-carcinoma"
      },
      {
        "slug": "palmoplantar-keratoderma",
        "name": "Thickening of palms and soles",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/palmoplantar-keratoderma"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}