{
  "url": "https://dantelabs.com/tr/genes/prkcd",
  "gene": {
    "slug": "prkcd",
    "symbol": "PRKCD",
    "name": "protein kinase C delta",
    "hgnc": "HGNC:9399",
    "summary": null,
    "location": "3p21.1",
    "locusType": "gene with protein product",
    "aliases": [
      "PKCδ"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000163932",
    "entrezId": 5580,
    "omim": [
      "176977"
    ],
    "uniprot": [
      "Q05655"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "3",
      "start": 53161209,
      "end": 53192717,
      "strand": "+",
      "ensemblTranscript": "ENST00000330452.8",
      "refseqTranscript": "NM_006254.4",
      "ensemblProtein": "ENSP00000331602.3",
      "refseqProtein": "NP_006245.2",
      "exons": [
        {
          "start": 53161209,
          "end": 53161428
        },
        {
          "start": 53165104,
          "end": 53165215
        },
        {
          "start": 53178404,
          "end": 53178537
        },
        {
          "start": 53179577,
          "end": 53179776
        },
        {
          "start": 53181207,
          "end": 53181267
        },
        {
          "start": 53181444,
          "end": 53181606
        },
        {
          "start": 53181701,
          "end": 53181732
        },
        {
          "start": 53183121,
          "end": 53183206
        },
        {
          "start": 53183452,
          "end": 53183581
        },
        {
          "start": 53184874,
          "end": 53184974
        },
        {
          "start": 53185604,
          "end": 53185700
        },
        {
          "start": 53185927,
          "end": 53186027
        },
        {
          "start": 53186167,
          "end": 53186340
        },
        {
          "start": 53186604,
          "end": 53186695
        },
        {
          "start": 53187340,
          "end": 53187402
        },
        {
          "start": 53188720,
          "end": 53188858
        },
        {
          "start": 53189058,
          "end": 53189246
        },
        {
          "start": 53189873,
          "end": 53190001
        },
        {
          "start": 53192108,
          "end": 53192717
        }
      ],
      "cds": {
        "start": 53178423,
        "end": 53192266
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "3",
      "start": 53190025,
      "end": 53226733,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 52676963,
      "end": 53676962,
      "genes": [
        {
          "symbol": "PBRM1",
          "ensemblId": "ENSG00000163939",
          "biotype": "protein_coding",
          "start": 52544271,
          "end": 52685979,
          "strand": "-",
          "slug": "pbrm1"
        },
        {
          "symbol": "GNL3",
          "ensemblId": "ENSG00000163938",
          "biotype": "protein_coding",
          "start": 52681156,
          "end": 52696160,
          "strand": "+",
          "slug": "gnl3"
        },
        {
          "symbol": "GLT8D1",
          "ensemblId": "ENSG00000016864",
          "biotype": "protein_coding",
          "start": 52691527,
          "end": 52706368,
          "strand": "-",
          "slug": "glt8d1"
        },
        {
          "symbol": "SPCS1",
          "ensemblId": "ENSG00000114902",
          "biotype": "protein_coding",
          "start": 52704955,
          "end": 52711148,
          "strand": "+",
          "slug": "spcs1"
        },
        {
          "symbol": "NEK4",
          "ensemblId": "ENSG00000114904",
          "biotype": "protein_coding",
          "start": 52708444,
          "end": 52770973,
          "strand": "-",
          "slug": "nek4"
        },
        {
          "symbol": "ITIH1",
          "ensemblId": "ENSG00000055957",
          "biotype": "protein_coding",
          "start": 52777559,
          "end": 52792068,
          "strand": "+",
          "slug": "itih1"
        },
        {
          "symbol": "ITIH3",
          "ensemblId": "ENSG00000162267",
          "biotype": "protein_coding",
          "start": 52794450,
          "end": 52809881,
          "strand": "+",
          "slug": "itih3"
        },
        {
          "symbol": "ITIH4",
          "ensemblId": "ENSG00000055955",
          "biotype": "protein_coding",
          "start": 52812918,
          "end": 52831069,
          "strand": "-",
          "slug": "itih4"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000243696",
          "biotype": "protein_coding",
          "start": 52813282,
          "end": 52835729,
          "strand": "-"
        },
        {
          "symbol": "MUSTN1",
          "ensemblId": "ENSG00000272573",
          "biotype": "protein_coding",
          "start": 52833113,
          "end": 52835222,
          "strand": "-",
          "slug": "mustn1"
        },
        {
          "symbol": "STIMATE-MUSTN1",
          "ensemblId": "ENSG00000248592",
          "biotype": "protein_coding",
          "start": 52833121,
          "end": 52897562,
          "strand": "-",
          "slug": "stimate-mustn1"
        },
        {
          "symbol": "STIMATE",
          "ensemblId": "ENSG00000213533",
          "biotype": "protein_coding",
          "start": 52836219,
          "end": 52897621,
          "strand": "-",
          "slug": "stimate"
        },
        {
          "symbol": "SFMBT1",
          "ensemblId": "ENSG00000163935",
          "biotype": "protein_coding",
          "start": 52903345,
          "end": 53046750,
          "strand": "-",
          "slug": "sfmbt1"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000272305",
          "biotype": "protein_coding",
          "start": 52969119,
          "end": 53099453,
          "strand": "-"
        },
        {
          "symbol": "RFT1",
          "ensemblId": "ENSG00000163933",
          "biotype": "protein_coding",
          "start": 53048135,
          "end": 53130661,
          "strand": "-",
          "slug": "rft1"
        },
        {
          "symbol": "TKT",
          "ensemblId": "ENSG00000163931",
          "biotype": "protein_coding",
          "start": 53223040,
          "end": 53256055,
          "strand": "-",
          "slug": "tkt"
        },
        {
          "symbol": "DCP1A",
          "ensemblId": "ENSG00000272886",
          "biotype": "protein_coding",
          "start": 53283429,
          "end": 53347683,
          "strand": "-",
          "slug": "dcp1a"
        },
        {
          "symbol": "CACNA1D",
          "ensemblId": "ENSG00000157388",
          "biotype": "protein_coding",
          "start": 53328963,
          "end": 53813733,
          "strand": "+",
          "slug": "cacna1d"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "autoimmune-disease",
        "name": "Otoimmün Hastalık",
        "diseases": [
          {
            "mondoId": "MONDO:0007179",
            "name": "Otoimmün Hastalık",
            "genes": 20,
            "inheritance": null,
            "description": "Bireyin kendi doku bileşenlerine karşı gelişen hümoral veya hücresel bağışıklık yanıtlarından kaynaklanan, bir organın veya birden fazla organın işlev kaybı ya da doku yıkımıyla sonuçlanan bir bozukluktur. Sistemik (örn. sistemik lupus eritematozus) veya organa özgü (örn. tiroidit) olabilir.",
            "management": null,
            "evidence": {
              "gencc": [
                "ClinGen",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/tr/conditions/autoimmune-disease"
      },
      {
        "slug": "autoimmune-lymphoproliferative-syndrome",
        "name": "Otoimmün Lenfoproliferatif Sendrom (ALPS)",
        "diseases": [
          {
            "mondoId": "MONDO:0017979",
            "name": "Otoimmün lenfoproliferatif sendrom",
            "genes": 7,
            "inheritance": null,
            "description": "FAS, FASLG, CASP10 ve ilgili apoptoz genlerindeki değişikliklerin neden olduğu kronik lenf düğümü ve dalak büyümesi, otoimmün sitopeniler ve artmış çift negatif T hücreleri.",
            "management": "Tanı; sitopeniler için sirolimus veya diğer immünsupresyon tedavilerinin uygulanmasına, gereksiz splenektomiden kaçınılmasına, lenfoma açısından dikkatli izlenmeye ve aile bireylerinin test edilmesine olanak tanır.",
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": false,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/tr/conditions/autoimmune-lymphoproliferative-syndrome"
      },
      {
        "slug": "systemic-lupus-erythematosus",
        "name": "Sistemik Lupus Eritematozus",
        "diseases": [
          {
            "mondoId": "MONDO:0007915",
            "name": "Sistemik Lupus Eritematozus",
            "genes": 6,
            "inheritance": null,
            "description": "Tipik olarak vaskülopati ve otoantikor üretimiyle ilişkili, birden fazla organı etkileyen otoimmün bir hastalıktır. Hastaların çoğunda antinükleer antikorlar (ANA) bulunur. Anti-dsDNA veya anti-Smith antikorlarının varlığı yüksek düzeyde spesifiktir.",
            "management": "Standart SLE: hidroksiklorokin, mikofenolat, belimumab, anifrolumab; Komplemen eksikliğine bağlı lupus: taze donmuş plazma (FFP) replasmanı; İnterferonopati: anifrolumab, JAK inhibitörleri; Tümü için: güneşten korunma, kardiyovasküler risk yönetimi, gebelik planlaması",
            "evidence": {
              "gencc": [
                "ClinGen"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/tr/conditions/systemic-lupus-erythematosus"
      },
      {
        "slug": "immunodeficiency-disease",
        "name": "Diğer Doğuştan İmmün Yetmezlikler",
        "diseases": [
          {
            "mondoId": "MONDO:0003778",
            "name": "Bağışıklık yetmezliğinin kalıtsal formu",
            "genes": 114,
            "inheritance": null,
            "description": "Tek genlerdeki değişikliklerden kaynaklanan, vücudun enfeksiyonlarla savaşma veya iltihaplanmayı düzenleme becerisini etkileyen kalıtsal bağışıklık sistemi bozuklukları.",
            "management": null,
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": false,
            "broad": true
          }
        ],
        "url": "https://dantelabs.com/tr/conditions/immunodeficiency-disease"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-natural-killer-cell-physiology",
        "name": "Abnormal natural killer cell physiology",
        "systems": [
          "abnormal-cellular-phenotype",
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/abnormal-natural-killer-cell-physiology"
      },
      {
        "slug": "absent-circulating-isohemagglutinin",
        "name": "Absent circulating isohemagglutinin",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/absent-circulating-isohemagglutinin"
      },
      {
        "slug": "anticardiolipin-igg-antibody-positivity",
        "name": "Anticardiolipin IgG antibody positivity",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/anticardiolipin-igg-antibody-positivity"
      },
      {
        "slug": "antinuclear-antibody-positivity",
        "name": "Antinuclear antibody positivity",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/antinuclear-antibody-positivity"
      },
      {
        "slug": "arthritis",
        "name": "Arthritis",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/arthritis"
      },
      {
        "slug": "autoimmune-hemolytic-anemia",
        "name": "Autoimmune hemolytic anemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/autoimmune-hemolytic-anemia"
      },
      {
        "slug": "autoimmune-thrombocytopenia",
        "name": "Autoimmune thrombocytopenia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/autoimmune-thrombocytopenia"
      },
      {
        "slug": "autoimmunity",
        "name": "Autoimmunity",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "url": "https://dantelabs.com/traits/autoimmunity"
      },
      {
        "slug": "decreased-circulating-complement-c3-concentration",
        "name": "Decreased circulating complement C3 concentration",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/decreased-circulating-complement-c3-concentration"
      },
      {
        "slug": "decreased-circulating-complement-c4-concentration",
        "name": "Decreased circulating complement C4 concentration",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/decreased-circulating-complement-c4-concentration"
      },
      {
        "slug": "decreased-class-switched-memory-b-cell-proportion",
        "name": "Decreased class-switched memory B cell proportion",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/decreased-class-switched-memory-b-cell-proportion"
      },
      {
        "slug": "decreased-memory-b-cell-proportion",
        "name": "Decreased memory B cell proportion",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/decreased-memory-b-cell-proportion"
      },
      {
        "slug": "elevated-circulating-alanine-aminotransferase-concentration",
        "name": "Elevated circulating alanine aminotransferase concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/elevated-circulating-alanine-aminotransferase-concentration"
      },
      {
        "slug": "elevated-circulating-aspartate-aminotransferase-concentration",
        "name": "Elevated circulating aspartate aminotransferase concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/elevated-circulating-aspartate-aminotransferase-concentration"
      },
      {
        "slug": "elevated-circulating-c-reactive-protein-concentration",
        "name": "Elevated circulating C-reactive protein concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/elevated-circulating-c-reactive-protein-concentration"
      },
      {
        "slug": "hepatomegaly",
        "name": "Enlarged liver",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hepatomegaly"
      },
      {
        "slug": "hepatosplenomegaly",
        "name": "Enlarged liver and spleen",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hepatosplenomegaly"
      },
      {
        "slug": "recurrent-fever",
        "name": "Episodic fever",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-fever"
      },
      {
        "slug": "erythematous-macule",
        "name": "Erythematous macule",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/erythematous-macule"
      },
      {
        "slug": "follicular-hyperplasia",
        "name": "Follicular hyperplasia",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/follicular-hyperplasia"
      },
      {
        "slug": "recurrent-urinary-tract-infections",
        "name": "Frequent urinary tract infections",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-urinary-tract-infections"
      },
      {
        "slug": "generalized-lymphadenopathy",
        "name": "Generalized swelling of lymph nodes",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/generalized-lymphadenopathy"
      },
      {
        "slug": "alopecia",
        "name": "Hair loss",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/alopecia"
      },
      {
        "slug": "elevated-erythrocyte-sedimentation-rate",
        "name": "High ESR",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/elevated-erythrocyte-sedimentation-rate"
      },
      {
        "slug": "increased-circulating-immunoglobulin-concentration",
        "name": "Increased antibody level in blood",
        "systems": [
          "abnormal-cellular-phenotype",
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/increased-circulating-immunoglobulin-concentration"
      },
      {
        "slug": "increased-cd21low-b-cell-proportion",
        "name": "Increased CD21low B cell proportion",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/increased-cd21low-b-cell-proportion"
      },
      {
        "slug": "splenomegaly",
        "name": "Increased spleen size",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/splenomegaly"
      },
      {
        "slug": "increased-total-b-cell-count",
        "name": "Increased total B cell count",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/increased-total-b-cell-count"
      },
      {
        "slug": "lymphoproliferative-disorder",
        "name": "Lymphoproliferative disorder",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "neoplasm"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/lymphoproliferative-disorder"
      },
      {
        "slug": "membranous-nephropathy",
        "name": "Membranous nephropathy",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/membranous-nephropathy"
      },
      {
        "slug": "nephrotic-syndrome",
        "name": "Nephrotic syndrome",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/nephrotic-syndrome"
      },
      {
        "slug": "obstruction-of-the-superior-vena-cava",
        "name": "Obstruction of the superior vena cava",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/obstruction-of-the-superior-vena-cava"
      },
      {
        "slug": "persistent-ebv-viremia",
        "name": "Persistent EBV viremia",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/persistent-ebv-viremia"
      },
      {
        "slug": "recurrent-lower-respiratory-tract-infections",
        "name": "Recurrent chest infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-lower-respiratory-tract-infections"
      },
      {
        "slug": "recurrent-upper-respiratory-tract-infections",
        "name": "Recurrent colds",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-upper-respiratory-tract-infections"
      },
      {
        "slug": "recurrent-infections",
        "name": "Recurrent infections",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-infections"
      },
      {
        "slug": "recurrent-otitis-media",
        "name": "Recurrent middle ear infection",
        "systems": [
          "abnormality-of-the-ear",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-otitis-media"
      },
      {
        "slug": "recurrent-sinusitis",
        "name": "Recurrent sinus disease",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-sinusitis"
      },
      {
        "slug": "stage-5-chronic-kidney-disease",
        "name": "Stage 5 chronic kidney disease",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/stage-5-chronic-kidney-disease"
      },
      {
        "slug": "lymphadenopathy",
        "name": "Swollen lymph nodes",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/lymphadenopathy"
      },
      {
        "slug": "mediastinal-lymphadenopathy",
        "name": "Swollen lymph nodes in center of chest",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-thoracic-cavity"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/mediastinal-lymphadenopathy"
      }
    ],
    "related": [
      {
        "slug": "c1qa",
        "symbol": "C1QA",
        "name": "complement C1q A chain",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/c1qa"
      },
      {
        "slug": "casp10",
        "symbol": "CASP10",
        "name": "caspase 10",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/casp10"
      },
      {
        "slug": "casp8",
        "symbol": "CASP8",
        "name": "caspase 8",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/casp8"
      },
      {
        "slug": "ctla4",
        "symbol": "CTLA4",
        "name": "cytotoxic T-lymphocyte associated protein 4",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/ctla4"
      },
      {
        "slug": "fas",
        "symbol": "FAS",
        "name": "Fas cell surface death receptor",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/fas"
      },
      {
        "slug": "faslg",
        "symbol": "FASLG",
        "name": "Fas ligand",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/faslg"
      },
      {
        "slug": "kras",
        "symbol": "KRAS",
        "name": "KRas proto-oncogene, GTPase",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/kras"
      },
      {
        "slug": "trex1",
        "symbol": "TREX1",
        "name": "three prime repair exonuclease 1",
        "shared": 3,
        "url": "https://dantelabs.com/tr/genes/trex1"
      },
      {
        "slug": "dnase1l3",
        "symbol": "DNASE1L3",
        "name": "deoxyribonuclease 1L3",
        "shared": 2,
        "url": "https://dantelabs.com/tr/genes/dnase1l3"
      },
      {
        "slug": "sat1",
        "symbol": "SAT1",
        "name": "spermidine/spermine N1-acetyltransferase 1",
        "shared": 2,
        "url": "https://dantelabs.com/tr/genes/sat1"
      },
      {
        "slug": "stat1",
        "symbol": "STAT1",
        "name": "signal transducer and activator of transcription 1",
        "shared": 2,
        "url": "https://dantelabs.com/tr/genes/stat1"
      },
      {
        "slug": "stat3",
        "symbol": "STAT3",
        "name": "signal transducer and activator of transcription 3",
        "shared": 2,
        "url": "https://dantelabs.com/tr/genes/stat3"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}