{
  "url": "https://dantelabs.com/tr/genes/exoc6b",
  "gene": {
    "slug": "exoc6b",
    "symbol": "EXOC6B",
    "name": "exocyst complex component 6B",
    "hgnc": "HGNC:17085",
    "summary": null,
    "location": "2p13.2",
    "locusType": "gene with protein product",
    "aliases": [
      "KIAA0919"
    ],
    "previousSymbols": [
      "SEC15L2",
      "SEC15B"
    ],
    "ensemblId": "ENSG00000144036",
    "entrezId": 23233,
    "omim": [
      "607880"
    ],
    "uniprot": [
      "Q9Y2D4"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "2",
      "start": 72175984,
      "end": 72826033,
      "strand": "-",
      "ensemblTranscript": "ENST00000272427.11",
      "refseqTranscript": "NM_015189.3",
      "ensemblProtein": "ENSP00000272427.7",
      "refseqProtein": "NP_056004.1",
      "exons": [
        {
          "start": 72175984,
          "end": 72179461
        },
        {
          "start": 72184075,
          "end": 72184187
        },
        {
          "start": 72334947,
          "end": 72335020
        },
        {
          "start": 72379729,
          "end": 72379870
        },
        {
          "start": 72465160,
          "end": 72465339
        },
        {
          "start": 72480616,
          "end": 72480750
        },
        {
          "start": 72492318,
          "end": 72492429
        },
        {
          "start": 72495430,
          "end": 72495539
        },
        {
          "start": 72496454,
          "end": 72496559
        },
        {
          "start": 72498454,
          "end": 72498551
        },
        {
          "start": 72499901,
          "end": 72499972
        },
        {
          "start": 72513132,
          "end": 72513252
        },
        {
          "start": 72514634,
          "end": 72514680
        },
        {
          "start": 72515043,
          "end": 72515126
        },
        {
          "start": 72559453,
          "end": 72559521
        },
        {
          "start": 72575492,
          "end": 72575668
        },
        {
          "start": 72718103,
          "end": 72718307
        },
        {
          "start": 72731007,
          "end": 72731052
        },
        {
          "start": 72731155,
          "end": 72731245
        },
        {
          "start": 72733071,
          "end": 72733118
        },
        {
          "start": 72741304,
          "end": 72741469
        },
        {
          "start": 72825798,
          "end": 72826033
        }
      ],
      "cds": {
        "start": 72179335,
        "end": 72825910
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "2",
      "start": 72403113,
      "end": 73053170,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 71525934,
      "end": 73476083,
      "genes": [
        {
          "symbol": "DYSF",
          "ensemblId": "ENSG00000135636",
          "biotype": "protein_coding",
          "start": 71453495,
          "end": 71686763,
          "strand": "+",
          "slug": "dysf"
        },
        {
          "symbol": "CYP26B1",
          "ensemblId": "ENSG00000003137",
          "biotype": "protein_coding",
          "start": 72129238,
          "end": 72148430,
          "strand": "-",
          "slug": "cyp26b1"
        },
        {
          "symbol": "SPR",
          "ensemblId": "ENSG00000116096",
          "biotype": "protein_coding",
          "start": 72887374,
          "end": 72892158,
          "strand": "+",
          "slug": "spr"
        },
        {
          "symbol": "EMX1",
          "ensemblId": "ENSG00000135638",
          "biotype": "protein_coding",
          "start": 72916184,
          "end": 72936071,
          "strand": "+",
          "slug": "emx1"
        },
        {
          "symbol": "SFXN5",
          "ensemblId": "ENSG00000144040",
          "biotype": "protein_coding",
          "start": 72939248,
          "end": 73075619,
          "strand": "-",
          "slug": "sfxn5"
        },
        {
          "symbol": "RAB11FIP5",
          "ensemblId": "ENSG00000135631",
          "biotype": "protein_coding",
          "start": 73073382,
          "end": 73156721,
          "strand": "-",
          "slug": "rab11fip5"
        },
        {
          "symbol": "NOTO",
          "ensemblId": "ENSG00000214513",
          "biotype": "protein_coding",
          "start": 73202570,
          "end": 73212513,
          "strand": "+",
          "slug": "noto"
        },
        {
          "symbol": "SMYD5",
          "ensemblId": "ENSG00000135632",
          "biotype": "protein_coding",
          "start": 73214222,
          "end": 73227229,
          "strand": "+",
          "slug": "smyd5"
        },
        {
          "symbol": "PRADC1",
          "ensemblId": "ENSG00000135617",
          "biotype": "protein_coding",
          "start": 73228008,
          "end": 73233262,
          "strand": "-",
          "slug": "pradc1"
        },
        {
          "symbol": "CCT7",
          "ensemblId": "ENSG00000135624",
          "biotype": "protein_coding",
          "start": 73233420,
          "end": 73253282,
          "strand": "+",
          "slug": "cct7"
        },
        {
          "symbol": "FBXO41",
          "ensemblId": "ENSG00000163013",
          "biotype": "protein_coding",
          "start": 73254682,
          "end": 73284478,
          "strand": "-",
          "slug": "fbxo41"
        },
        {
          "symbol": "EGR4",
          "ensemblId": "ENSG00000135625",
          "biotype": "protein_coding",
          "start": 73290927,
          "end": 73293721,
          "strand": "-",
          "slug": "egr4"
        },
        {
          "symbol": "ALMS1",
          "ensemblId": "ENSG00000116127",
          "biotype": "protein_coding",
          "start": 73385758,
          "end": 73625166,
          "strand": "+",
          "slug": "alms1"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "delayed-ability-to-walk",
        "name": "Delayed ability to walk",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/delayed-ability-to-walk"
      },
      {
        "slug": "delayed-ossification-of-carpal-bones",
        "name": "Delayed maturation of wrist bone",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/delayed-ossification-of-carpal-bones"
      },
      {
        "slug": "patellar-dislocation",
        "name": "Dislocated kneecap",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/patellar-dislocation"
      },
      {
        "slug": "dislocated-radial-head",
        "name": "Dislocated radial head",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/dislocated-radial-head"
      },
      {
        "slug": "joint-hypermobility",
        "name": "Double-Jointed",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/joint-hypermobility"
      },
      {
        "slug": "pes-planus",
        "name": "Dropped arches",
        "systems": [
          "abnormality-of-limbs"
        ],
        "url": "https://dantelabs.com/traits/pes-planus"
      },
      {
        "slug": "platyspondyly",
        "name": "Flattened vertebrae",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/platyspondyly"
      },
      {
        "slug": "hip-dislocation",
        "name": "Hip dislocation",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hip-dislocation"
      },
      {
        "slug": "irregular-vertebral-endplates",
        "name": "Irregular vertebral endplates",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/irregular-vertebral-endplates"
      },
      {
        "slug": "metaphyseal-irregularity",
        "name": "Irregular wide portion of a long bone",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/metaphyseal-irregularity"
      },
      {
        "slug": "knee-dislocation",
        "name": "Knee dislocation",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/knee-dislocation"
      },
      {
        "slug": "dolichocephaly",
        "name": "Long, narrow head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/dolichocephaly"
      },
      {
        "slug": "multiple-joint-dislocation",
        "name": "Multiple joint dislocation",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/multiple-joint-dislocation"
      },
      {
        "slug": "narrow-vertebral-interpedicular-distance",
        "name": "Narrow vertebral interpedicular distance",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/narrow-vertebral-interpedicular-distance"
      },
      {
        "slug": "obesity",
        "name": "Obesity",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/obesity"
      },
      {
        "slug": "scoliosis",
        "name": "Scoliosis",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/scoliosis"
      },
      {
        "slug": "short-neck",
        "name": "Short neck",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/short-neck"
      },
      {
        "slug": "short-femoral-neck",
        "name": "Short neck of thighbone",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/short-femoral-neck"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "carpal-bone-hypoplasia",
        "name": "Small carpal bones",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/carpal-bone-hypoplasia"
      },
      {
        "slug": "spondyloepimetaphyseal-dysplasia",
        "name": "Spondyloepimetaphyseal dysplasia",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/spondyloepimetaphyseal-dysplasia"
      },
      {
        "slug": "tapered-finger",
        "name": "Tapered finger",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/tapered-finger"
      },
      {
        "slug": "thin-ribs",
        "name": "Thin ribs",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/thin-ribs"
      },
      {
        "slug": "hypoplasia-of-the-ulna",
        "name": "Underdeveloped inner large forearm bone",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/hypoplasia-of-the-ulna"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}