{ "url": "https://dantelabs.com/tr/genes/atl1", "gene": { "slug": "atl1", "symbol": "ATL1", "name": "atlastin GTPase 1", "hgnc": "HGNC:11231", "summary": null, "location": "14q22.1", "locusType": "gene with protein product", "aliases": [ "FSP1", "AD-FSP" ], "previousSymbols": [ "SPG3", "SPG3A" ], "ensemblId": "ENSG00000198513", "entrezId": 51062, "omim": [ "606439" ], "uniprot": [ "Q8WXF7" ], "model": { "build": "GRCh38", "release": "v1.5", "chrom": "14", "start": 50560145, "end": 50633045, "strand": "+", "ensemblTranscript": "ENST00000358385.12", "refseqTranscript": "NM_015915.5", "ensemblProtein": "ENSP00000351155.7", "refseqProtein": "NP_056999.2", "exons": [ { "start": 50560145, "end": 50560299 }, { "start": 50587831, "end": 50588078 }, { "start": 50590941, "end": 50591075 }, { "start": 50591535, "end": 50591639 }, { "start": 50593846, "end": 50593896 }, { "start": 50595576, "end": 50595632 }, { "start": 50613259, "end": 50613351 }, { "start": 50614373, "end": 50614511 }, { "start": 50620599, "end": 50620726 }, { "start": 50621843, "end": 50621899 }, { "start": 50623177, "end": 50623248 }, { "start": 50628031, "end": 50628462 }, { "start": 50629995, "end": 50630009 }, { "start": 50632229, "end": 50633045 } ], "cds": { "start": 50560266, "end": 50632339 } }, "grch37": { "build": "GRCh37", "release": "87", "chrom": "14", "start": 50999227, "end": 51099786, "strand": "+" }, "neighbourhood": { "release": "116", "start": 50096595, "end": 51096594, "genes": [ { "symbol": "VCPKMT", "ensemblId": "ENSG00000100483", "biotype": "protein_coding", "start": 50108631, "end": 50116600, "strand": "-", "slug": "vcpkmt" }, { "symbol": "SOS2", "ensemblId": "ENSG00000100485", "biotype": "protein_coding", "start": 50116801, "end": 50231930, "strand": "-", "slug": "sos2" }, { "symbol": "L2HGDH", "ensemblId": "ENSG00000087299", "biotype": "protein_coding", "start": 50237563, "end": 50312243, "strand": "-", "slug": "l2hgdh" }, { "symbol": "DMAC2L", "ensemblId": "ENSG00000125375", "biotype": "protein_coding", "start": 50311516, "end": 50356756, "strand": "+", "slug": "dmac2l" }, { "symbol": "CDKL1", "ensemblId": "ENSG00000100490", "biotype": "protein_coding", "start": 50326265, "end": 50416461, "strand": "-", "slug": "cdkl1" }, { "symbol": "MAP4K5", "ensemblId": "ENSG00000012983", "biotype": "protein_coding", "start": 50417845, "end": 50561126, "strand": "-", "slug": "map4k5" }, { "symbol": "SAV1", "ensemblId": "ENSG00000151748", "biotype": "protein_coding", "start": 50626616, "end": 50668600, "strand": "-", "slug": "sav1" }, { "symbol": "NIN", "ensemblId": "ENSG00000100503", "biotype": "protein_coding", "start": 50719763, "end": 50832038, "strand": "-", "slug": "nin" }, { "symbol": "PYGL", "ensemblId": "ENSG00000100504", "biotype": "protein_coding", "start": 50857891, "end": 50944734, "strand": "-", "slug": "pygl" }, { "symbol": "ABHD12B", "ensemblId": "ENSG00000131969", "biotype": "protein_coding", "start": 50872046, "end": 50904970, "strand": "+", "slug": "abhd12b" }, { "symbol": "TRIM9", "ensemblId": "ENSG00000100505", "biotype": "protein_coding", "start": 50975254, "end": 51096084, "strand": "-", "slug": "trim9" } ], "truncated": false }, "reports": [ { "slug": "hereditary-sensory-and-autonomic-neuropathies", "name": "Kalıtsal Duyusal ve Otonom Nöropatiler (Familyal Disotonomi Dahil)", "diseases": [ { "mondoId": "MONDO:0015364", "name": "Kalıtsal Duyusal ve Otonom Nöropati", "genes": 21, "inheritance": null, "description": "Familyal disotonomi (ELP1), HSAN1 (SPTLC1/SPTLC2), HSAN2 (WNK1, RETREG1) ve konjenital ağrı duyarsızlığı (NTRK1, SCN9A, PRDM12) dahil olmak üzere bir nöropati grubudur. Bunların çoğu çekiniktir; HSAN1 ise baskındır.", "management": "Fark edilmeyen yaralanmalara, yanıklara ve enfeksiyonlara karşı koruma, otonom semptomların yönetimi ve yakınlar için taşıyıcılık testi (familyal disotonomi, Aşkenazi Yahudi taşıyıcı taramasına dahildir).", "evidence": { "gencc": [ "ClinGen", "Labcorp Genetics (formerly Invitae)", "PanelApp Australia" ], "clingen": "Definitive", "acmgSf": false, "inheritance": [ "autosomal-dominant" ] }, "sameAsReport": false, "broad": false } ], "url": "https://dantelabs.com/tr/conditions/hereditary-sensory-and-autonomic-neuropathies" }, { "slug": "hereditary-spastic-paraplegia", "name": "Kalıtsal Spastik Paraplezi", "diseases": [ { "mondoId": "MONDO:0008437", "name": "Kalıtsal Spastik Paraplezi 3a", "genes": 1, "inheritance": "autosomal-dominant", "description": "Hastalığın nedeninin ATL1 geninde bir mutasyon olduğu herhangi bir kalıtsal spastik paraplezi.", "management": null, "evidence": { "gencc": [ "Ambry Genetics", "G2P", "Labcorp Genetics (formerly Invitae)", "PanelApp Australia" ], "acmgSf": false, "inheritance": [ "autosomal-dominant", "autosomal-recessive" ] }, "sameAsReport": false, "broad": false }, { "mondoId": "MONDO:0019064", "name": "Herediter Spastik Parapleji (Tüm Tipler)", "genes": 66, "inheritance": null, "description": "SPG4 (SPAST), en yaygın dominant form olmak üzere ve SPG5A, SPG6, SPG10, SPG18, SPG30 ile SPG31 dahil olmak üzere tüm herediter spastik paraplejileri kapsayan şemsiye terim.", "management": null, "evidence": { "gencc": [ "Ambry Genetics", "G2P", "Labcorp Genetics (formerly Invitae)", "PanelApp Australia" ], "acmgSf": false, "inheritance": [ "autosomal-dominant", "autosomal-recessive" ] }, "sameAsReport": false, "broad": true } ], "url": "https://dantelabs.com/tr/conditions/hereditary-spastic-paraplegia" } ], "pharmacogenomics": [], "traits": [], "phenotypes": [ { "slug": "gait-disturbance", "name": "Abnormal gait", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/gait-disturbance" }, { "slug": "ankle-clonus", "name": "Abnormal rhythmic movements of ankle", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system", "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/ankle-clonus" }, { "slug": "gait-imbalance", "name": "Abnormality of balance", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/gait-imbalance" }, { "slug": "abnormality-of-the-autonomic-nervous-system", "name": "Abnormality of the autonomic nervous system", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormality-of-the-autonomic-nervous-system" }, { "slug": "gastroesophageal-reflux", "name": "Acid reflux", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/gastroesophageal-reflux" }, { "slug": "autoamputation-of-digits", "name": "Autoamputation of digits", "systems": [ "abnormality-of-limbs" ], "url": "https://dantelabs.com/traits/autoamputation-of-digits" }, { "slug": "babinski-sign", "name": "Babinski sign", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/babinski-sign" }, { "slug": "osteomyelitis", "name": "Bone infection", "systems": [ "abnormality-of-the-immune-system", "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/osteomyelitis" }, { "slug": "cough", "name": "Cough", "systems": [ "abnormality-of-the-respiratory-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/cough" }, { "slug": "decreased-amplitude-of-sensory-action-potentials", "name": "Decreased amplitude of sensory action potentials", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/decreased-amplitude-of-sensory-action-potentials" }, { "slug": "distal-sensory-impairment", "name": "Decreased sensation in extremities", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/distal-sensory-impairment" }, { "slug": "impaired-distal-tactile-sensation", "name": "Decreased touch sensation in extremities", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/impaired-distal-tactile-sensation" }, { "slug": "degeneration-of-the-lateral-corticospinal-tracts", "name": "Degeneration of the lateral corticospinal tracts", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/degeneration-of-the-lateral-corticospinal-tracts" }, { "slug": "dysarthria", "name": "Difficulty articulating speech", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/dysarthria" }, { "slug": "distal-lower-limb-amyotrophy", "name": "Distal lower limb amyotrophy", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/distal-lower-limb-amyotrophy" }, { "slug": "distal-lower-limb-muscle-weakness", "name": "Distal lower limb muscle weakness", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/distal-lower-limb-muscle-weakness" }, { "slug": "distal-amyotrophy", "name": "Distal muscle wasting", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/distal-amyotrophy" }, { "slug": "distal-sensory-impairment-of-all-modalities", "name": "Distal sensory impairment of all modalities", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/distal-sensory-impairment-of-all-modalities" }, { "slug": "emg-slow-motor-conduction", "name": "EMG: slow motor conduction", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/emg-slow-motor-conduction" }, { "slug": "foot-dorsiflexor-weakness", "name": "Foot drop", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/foot-dorsiflexor-weakness" }, { "slug": "frequent-falls", "name": "Frequent falls", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/frequent-falls" }, { "slug": "growth-delay", "name": "Growth delay", "systems": [ "growth-abnormality" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/growth-delay" }, { "slug": "hearing-impairment", "name": "Hearing impairment", "systems": [ "abnormality-of-the-ear" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hearing-impairment" }, { "slug": "steppage-gait", "name": "High stepping", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/steppage-gait" }, { "slug": "pes-cavus", "name": "High-arched foot", "systems": [ "abnormality-of-limbs" ], "url": "https://dantelabs.com/traits/pes-cavus" }, { "slug": "hyperesthesia", "name": "Hyperesthesia", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/hyperesthesia" }, { "slug": "hyperkeratosis", "name": "Hyperkeratosis", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hyperkeratosis" }, { "slug": "impaired-ability-to-dress-oneself", "name": "Impaired ability to dress oneself", "systems": [ "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/impaired-ability-to-dress-oneself" }, { "slug": "impaired-temperature-sensation", "name": "Impaired temperature sensation", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/impaired-temperature-sensation" }, { "slug": "impaired-vibration-sensation-in-the-lower-limbs", "name": "Impaired vibration sensation in the lower limbs", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/impaired-vibration-sensation-in-the-lower-limbs" }, { "slug": "impaired-vibratory-sensation", "name": "Impaired vibratory sensation", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/impaired-vibratory-sensation" }, { "slug": "inability-to-walk", "name": "Inability to walk", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/inability-to-walk" }, { "slug": "hyperreflexia", "name": "Increased reflexes", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/hyperreflexia" }, { "slug": "mild-intellectual-disability", "name": "Intellectual disability, mild", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/mild-intellectual-disability" }, { "slug": "hypohidrosis-or-hyperhidrosis", "name": "Lack of sweating or excessive sweating", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hypohidrosis-or-hyperhidrosis" }, { "slug": "paraplegia", "name": "Leg paralysis", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/paraplegia" }, { "slug": "limb-pain", "name": "Limb pain", "systems": [ "abnormality-of-the-musculoskeletal-system", "constitutional-symptom" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/limb-pain" }, { "slug": "urinary-incontinence", "name": "Loss of bladder control", "systems": [ "abnormality-of-the-genitourinary-system", "constitutional-symptom" ], "url": "https://dantelabs.com/traits/urinary-incontinence" }, { "slug": "lower-limb-hypertonia", "name": "Lower limb hypertonia", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/lower-limb-hypertonia" }, { "slug": "lower-limb-muscle-weakness", "name": "Lower limb muscle weakness", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/lower-limb-muscle-weakness" }, { "slug": "lower-limb-spasticity", "name": "Lower limb spasticity", "systems": [ "abnormality-of-the-musculoskeletal-system", "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/lower-limb-spasticity" }, { "slug": "motor-axonal-neuropathy", "name": "Motor axonal neuropathy", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/motor-axonal-neuropathy" }, { "slug": "motor-delay", "name": "Motor delay", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/motor-delay" }, { "slug": "muscle-weakness", "name": "Muscle weakness", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/muscle-weakness" }, { "slug": "neuropathic-arthropathy", "name": "Neuropathic arthropathy", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/neuropathic-arthropathy" }, { "slug": "skin-ulcer", "name": "Open skin sore", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/skin-ulcer" }, { "slug": "lower-limb-hyperreflexia", "name": "Overactive lower leg reflex", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/lower-limb-hyperreflexia" }, { "slug": "pain-insensitivity", "name": "Pain insensitivity", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/pain-insensitivity" }, { "slug": "penetrating-foot-ulcers", "name": "Penetrating foot ulcers", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/penetrating-foot-ulcers" }, { "slug": "peripheral-axonal-neuropathy", "name": "Peripheral axonal neuropathy", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/peripheral-axonal-neuropathy" }, { "slug": "peripheral-neuropathy", "name": "Peripheral neuropathy", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/peripheral-neuropathy" }, { "slug": "paresthesia", "name": "Pins and needles feeling", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/paresthesia" }, { "slug": "nail-dystrophy", "name": "Poor nail formation", "systems": [ "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/nail-dystrophy" }, { "slug": "poor-wound-healing", "name": "Poor wound healing", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/poor-wound-healing" }, { "slug": "rigidity", "name": "Rigidity", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/rigidity" }, { "slug": "scoliosis", "name": "Scoliosis", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "url": "https://dantelabs.com/traits/scoliosis" }, { "slug": "bradykinesia", "name": "Slow movements", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/bradykinesia" }, { "slug": "spastic-paraplegia", "name": "Spastic paraplegia", "systems": [ "abnormality-of-the-musculoskeletal-system", "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/spastic-paraplegia" }, { "slug": "spastic-gait", "name": "Spastic walk", "systems": [ "abnormality-of-the-musculoskeletal-system", "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/spastic-gait" }, { "slug": "pathologic-fracture", "name": "Spontaneous fracture", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/pathologic-fracture" }, { "slug": "tip-toe-gait", "name": "Toe walking", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/tip-toe-gait" }, { "slug": "trophic-changes-related-to-pain", "name": "Trophic changes related to pain", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/trophic-changes-related-to-pain" }, { "slug": "hypoplasia-of-the-corpus-callosum", "name": "Underdevelopment of part of brain called corpus callosum", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hypoplasia-of-the-corpus-callosum" }, { "slug": "urinary-bladder-sphincter-dysfunction", "name": "Urinary bladder sphincter dysfunction", "systems": [ "abnormality-of-the-genitourinary-system" ], "url": "https://dantelabs.com/traits/urinary-bladder-sphincter-dysfunction" }, { "slug": "urinary-urgency", "name": "Urinary urgency", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/urinary-urgency" }, { "slug": "distal-muscle-weakness", "name": "Weakness of outermost muscles", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/distal-muscle-weakness" } ], "related": [ { "slug": "kif1a", "symbol": "KIF1A", "name": "kinesin family member 1A", "shared": 2, "url": "https://dantelabs.com/tr/genes/kif1a" }, { "slug": "tecpr2", "symbol": "TECPR2", "name": "tectonin beta-propeller repeat containing 2", "shared": 2, "url": "https://dantelabs.com/tr/genes/tecpr2" }, { "slug": "abcd1", "symbol": "ABCD1", "name": "ATP binding cassette subfamily D member 1", "shared": 1, "url": "https://dantelabs.com/tr/genes/abcd1" }, { "slug": "abhd16a", "symbol": "ABHD16A", "name": "abhydrolase domain containing 16A, phospholipase", "shared": 1, "url": "https://dantelabs.com/tr/genes/abhd16a" }, { "slug": "aifm1", "symbol": "AIFM1", "name": "apoptosis inducing factor mitochondria associated 1", "shared": 1, "url": "https://dantelabs.com/tr/genes/aifm1" }, { "slug": "aldh18a1", "symbol": "ALDH18A1", "name": "aldehyde dehydrogenase 18 family member A1", "shared": 1, "url": "https://dantelabs.com/tr/genes/aldh18a1" }, { "slug": "amfr", "symbol": "AMFR", "name": "autocrine motility factor receptor", "shared": 1, "url": "https://dantelabs.com/tr/genes/amfr" }, { "slug": "ap4b1", "symbol": "AP4B1", "name": "adaptor related protein complex 4 subunit beta 1", "shared": 1, "url": "https://dantelabs.com/tr/genes/ap4b1" }, { "slug": "ap4e1", "symbol": "AP4E1", "name": "adaptor related protein complex 4 subunit epsilon 1", "shared": 1, "url": "https://dantelabs.com/tr/genes/ap4e1" }, { "slug": "ap4m1", "symbol": "AP4M1", "name": "adaptor related protein complex 4 subunit mu 1", "shared": 1, "url": "https://dantelabs.com/tr/genes/ap4m1" }, { "slug": "ap4s1", "symbol": "AP4S1", "name": "adaptor related protein complex 4 subunit sigma 1", "shared": 1, "url": "https://dantelabs.com/tr/genes/ap4s1" }, { "slug": "ap5z1", "symbol": "AP5Z1", "name": "adaptor related protein complex 5 subunit zeta 1", "shared": 1, "url": "https://dantelabs.com/tr/genes/ap5z1" } ], "sources": { "bundleId": "2026.10.17-8666dff2", "panel": "2026-10-17", "acmgSf": "SF v3.2" }, "locusKind": "proteinCoding" }, "variants": { "total": 0, "url": null, "items": [] } }