{
  "url": "https://dantelabs.com/traits/uterus-didelphys",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "uterus-didelphys",
    "id": "HP:0003762",
    "name": "Double uterus",
    "label": "Uterus didelphys",
    "definition": "A malformation of the uterus in which the uterus is present as a paired organ as a result of the failure of fusion of the mullerian ducts during embryogenesis.",
    "synonyms": [
      "Didelphic uteri",
      "Didelphic uterus",
      "Didelphyc uterus",
      "Doubling of uterus",
      "Duplex uterus",
      "Duplicated uterus",
      "Duplication of uterus",
      "Uterine didelphis",
      "Uterine didelphys",
      "Uterus didelphis",
      "Uterus didelphus",
      "Uterus duplex"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-uterus-morphology",
        "name": "Abnormal uterus morphology",
        "url": "https://dantelabs.com/traits/abnormal-uterus-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "hoxa13",
        "symbol": "HOXA13",
        "hgnc": "HGNC:5102",
        "name": "homeobox A13",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hoxa13"
      },
      {
        "slug": "intu",
        "symbol": "INTU",
        "hgnc": "HGNC:29239",
        "name": "inturned planar cell polarity protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/intu"
      },
      {
        "slug": "rbsn",
        "symbol": "RBSN",
        "hgnc": "HGNC:20759",
        "name": "rabenosyn, RAB effector",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbsn"
      },
      {
        "slug": "wt1",
        "symbol": "WT1",
        "hgnc": "HGNC:12796",
        "name": "WT1 transcription factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wt1"
      },
      {
        "slug": "dync2h1",
        "symbol": "DYNC2H1",
        "hgnc": "HGNC:2962",
        "name": "dynein cytoplasmic 2 heavy chain 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2h1"
      },
      {
        "slug": "dync2i1",
        "symbol": "DYNC2I1",
        "hgnc": "HGNC:21862",
        "name": "dynein 2 intermediate chain 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2i1"
      },
      {
        "slug": "dync2i2",
        "symbol": "DYNC2I2",
        "hgnc": "HGNC:28296",
        "name": "dynein 2 intermediate chain 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2i2"
      },
      {
        "slug": "fzd2",
        "symbol": "FZD2",
        "hgnc": "HGNC:4040",
        "name": "frizzled class receptor 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fzd2"
      },
      {
        "slug": "ift80",
        "symbol": "IFT80",
        "hgnc": "HGNC:29262",
        "name": "intraflagellar transport 80",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift80"
      },
      {
        "slug": "wdr35",
        "symbol": "WDR35",
        "hgnc": "HGNC:29250",
        "name": "WD repeat domain 35",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr35"
      },
      {
        "slug": "gata3",
        "symbol": "GATA3",
        "hgnc": "HGNC:4172",
        "name": "GATA binding protein 3",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gata3"
      },
      {
        "slug": "ppp1r12a",
        "symbol": "PPP1R12A",
        "hgnc": "HGNC:7618",
        "name": "protein phosphatase 1 regulatory subunit 12A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp1r12a"
      },
      {
        "slug": "axin1",
        "symbol": "AXIN1",
        "hgnc": "HGNC:903",
        "name": "axin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/axin1"
      }
    ]
  }
}