{
  "url": "https://dantelabs.com/traits/thyroid-adenoma",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "thyroid-adenoma",
    "id": "HP:0000854",
    "name": "Thyroid adenoma",
    "definition": "The presence of a adenoma of the thyroid gland.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      },
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "neoplasm-of-the-thyroid-gland",
        "name": "Neoplasm of the thyroid gland",
        "url": "https://dantelabs.com/traits/neoplasm-of-the-thyroid-gland"
      }
    ],
    "narrower": [
      {
        "slug": "hurthle-cell-thyroid-adenoma",
        "name": "Hurthle cell thyroid adenoma",
        "genes": 3,
        "url": "https://dantelabs.com/traits/hurthle-cell-thyroid-adenoma"
      }
    ],
    "genes": [
      {
        "slug": "cdkn1b",
        "symbol": "CDKN1B",
        "hgnc": "HGNC:1785",
        "name": "cyclin dependent kinase inhibitor 1B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdkn1b"
      },
      {
        "slug": "msh3",
        "symbol": "MSH3",
        "hgnc": "HGNC:7326",
        "name": "mutS homolog 3",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/msh3"
      },
      {
        "slug": "apc",
        "symbol": "APC",
        "hgnc": "HGNC:583",
        "name": "APC regulator of Wnt signaling pathway",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apc"
      },
      {
        "slug": "casp10",
        "symbol": "CASP10",
        "hgnc": "HGNC:1500",
        "name": "caspase 10",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/casp10"
      },
      {
        "slug": "fas",
        "symbol": "FAS",
        "hgnc": "HGNC:11920",
        "name": "Fas cell surface death receptor",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fas"
      },
      {
        "slug": "faslg",
        "symbol": "FASLG",
        "hgnc": "HGNC:11936",
        "name": "Fas ligand",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/faslg"
      },
      {
        "slug": "men1",
        "symbol": "MEN1",
        "hgnc": "HGNC:7010",
        "name": "menin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/men1"
      },
      {
        "slug": "pik3ca",
        "symbol": "PIK3CA",
        "hgnc": "HGNC:8975",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3ca"
      },
      {
        "slug": "pten",
        "symbol": "PTEN",
        "hgnc": "HGNC:9588",
        "name": "phosphatase and tensin homolog",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pten"
      }
    ]
  }
}