{
  "url": "https://dantelabs.com/traits/macrozoospermia",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "macrozoospermia",
    "id": "HP:0025437",
    "name": "Macrozoospermia",
    "definition": "Increased size of the head of sperm.",
    "synonyms": [
      "Macrocephalic sperm head"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-sperm-head-morphology",
        "name": "Abnormal sperm head morphology",
        "url": "https://dantelabs.com/traits/abnormal-sperm-head-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "aurkc",
        "symbol": "AURKC",
        "hgnc": "HGNC:11391",
        "name": "aurora kinase C",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aurkc"
      },
      {
        "slug": "cfap91",
        "symbol": "CFAP91",
        "hgnc": "HGNC:24010",
        "name": "cilia and flagella associated protein 91",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap91"
      },
      {
        "slug": "nup210l",
        "symbol": "NUP210L",
        "hgnc": "HGNC:29915",
        "name": "nucleoporin 210 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nup210l"
      }
    ]
  }
}