{ "url": "https://dantelabs.com/traits/hypothyroidism", "trait": { "bundleId": "2026.10.17-8666dff2", "release": "2026-09-01", "slug": "hypothyroidism", "id": "HP:0000821", "name": "Underactive thyroid", "label": "Hypothyroidism", "definition": "Deficiency of thyroid hormone.", "synonyms": [ "Low T4" ], "systems": [ { "slug": "abnormality-of-the-endocrine-system", "name": "Abnormality of the endocrine system", "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system" } ], "broader": [ { "slug": "abnormality-of-thyroid-physiology", "name": "Abnormal thyroid function", "url": "https://dantelabs.com/traits/abnormality-of-thyroid-physiology" } ], "narrower": [ { "slug": "central-hypothyroidism", "name": "Central hypothyroidism", "genes": 39, "url": "https://dantelabs.com/traits/central-hypothyroidism" }, { "slug": "congenital-hypothyroidism", "name": "Underactive thyroid gland from birth", "genes": 33, "url": "https://dantelabs.com/traits/congenital-hypothyroidism" }, { "slug": "compensated-hypothyroidism", "name": "Compensated hypothyroidism", "genes": 9, "url": "https://dantelabs.com/traits/compensated-hypothyroidism" }, { "slug": "primary-hypothyroidism", "name": "Primary hypothyroidism", "genes": 6, "url": "https://dantelabs.com/traits/primary-hypothyroidism" } ], "genes": [ { "slug": "atp11a", "symbol": "ATP11A", "hgnc": "HGNC:13552", "name": "ATPase phospholipid transporting 11A", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/atp11a" }, { "slug": "cdkn1b", "symbol": "CDKN1B", "hgnc": "HGNC:1785", "name": "cyclin dependent kinase inhibitor 1B", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/cdkn1b" }, { "slug": "dnah1", "symbol": "DNAH1", "hgnc": "HGNC:2940", "name": "dynein axonemal heavy chain 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/dnah1" }, { "slug": "fanci", "symbol": "FANCI", "hgnc": "HGNC:25568", "name": "FA complementation group I", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/fanci" }, { "slug": "farsa", "symbol": "FARSA", "hgnc": "HGNC:3592", "name": "phenylalanyl-tRNA synthetase subunit alpha", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/farsa" }, { "slug": "flvcr1", "symbol": "FLVCR1", "hgnc": "HGNC:24682", "name": "FLVCR choline and heme transporter 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/flvcr1" }, { "slug": "foxe1", "symbol": "FOXE1", "hgnc": "HGNC:3806", "name": "forkhead box E1", "frequency": "obligate", "diseases": 2, "url": "https://dantelabs.com/genes/foxe1" }, { "slug": "gtpbp2", "symbol": "GTPBP2", "hgnc": "HGNC:4670", "name": "GTP binding protein 2", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/gtpbp2" }, { "slug": "igsf1", "symbol": "IGSF1", "hgnc": "HGNC:5948", "name": "immunoglobulin superfamily member 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/igsf1" }, { "slug": "ikzf2", "symbol": "IKZF2", "hgnc": "HGNC:13177", "name": "IKAROS family zinc finger 2", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/ikzf2" }, { "slug": "il2ra", "symbol": "IL2RA", "hgnc": "HGNC:6008", "name": "interleukin 2 receptor subunit alpha", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/il2ra" }, { "slug": "il6st", "symbol": "IL6ST", "hgnc": "HGNC:6021", "name": "interleukin 6 cytokine family signal transducer", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/il6st" }, { "slug": "jkamp", "symbol": "JKAMP", "hgnc": "HGNC:20184", "name": "JNK1/MAPK8 associated membrane protein", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/jkamp" }, { "slug": "kars1", "symbol": "KARS1", "hgnc": "HGNC:6215", "name": "lysyl-tRNA synthetase 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/kars1" }, { "slug": "kdm6a", "symbol": "KDM6A", "hgnc": "HGNC:12637", "name": "lysine demethylase 6A", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/kdm6a" }, { "slug": "kmt2d", "symbol": "KMT2D", "hgnc": "HGNC:7133", "name": "lysine methyltransferase 2D", "frequency": "obligate", "diseases": 2, "url": "https://dantelabs.com/genes/kmt2d" }, { "slug": "lrrc7", "symbol": "LRRC7", "hgnc": "HGNC:18531", "name": "leucine rich repeat containing 7", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/lrrc7" }, { "slug": "lrrc8c", "symbol": "LRRC8C", "hgnc": "HGNC:25075", "name": "leucine rich repeat containing 8 VRAC subunit C", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/lrrc8c" }, { "slug": "mark2", "symbol": "MARK2", "hgnc": "HGNC:3332", "name": "microtubule affinity regulating kinase 2", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/mark2" }, { "slug": "mars1", "symbol": "MARS1", "hgnc": "HGNC:6898", "name": "methionyl-tRNA synthetase 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/mars1" }, { "slug": "msl2", "symbol": "MSL2", "hgnc": "HGNC:25544", "name": "MSL complex subunit 2", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/msl2" }, { "slug": "nkx2-5", "symbol": "NKX2-5", "hgnc": "HGNC:2488", "name": "NK2 homeobox 5", "frequency": "obligate", "diseases": 3, "url": "https://dantelabs.com/genes/nkx2-5" }, { "slug": "notch3", "symbol": "NOTCH3", "hgnc": "HGNC:7883", "name": "notch receptor 3", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/notch3" }, { "slug": "pax8", "symbol": "PAX8", "hgnc": "HGNC:8622", "name": "paired box 8", "frequency": "obligate", "diseases": 4, "url": "https://dantelabs.com/genes/pax8" }, { "slug": "pdcd1", "symbol": "PDCD1", "hgnc": "HGNC:8760", "name": "programmed cell death 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/pdcd1" }, { "slug": "pou1f1", "symbol": "POU1F1", "hgnc": "HGNC:9210", "name": "POU class 1 homeobox 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/pou1f1" }, { "slug": "ppfia3", "symbol": "PPFIA3", "hgnc": "HGNC:9247", "name": "PPFI scaffold protein A3", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/ppfia3" }, { "slug": "ptcra", "symbol": "PTCRA", "hgnc": "HGNC:21290", "name": "pre T cell antigen receptor alpha", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/ptcra" }, { "slug": "ptrh2", "symbol": "PTRH2", "hgnc": "HGNC:24265", "name": "peptidyl-tRNA hydrolase 2", "frequency": "obligate", "diseases": 2, "url": "https://dantelabs.com/genes/ptrh2" }, { "slug": "rfc4", "symbol": "RFC4", "hgnc": "HGNC:9972", "name": "replication factor C subunit 4", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/rfc4" }, { "slug": "sgpl1", "symbol": "SGPL1", "hgnc": "HGNC:10817", "name": "sphingosine-1-phosphate lyase 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/sgpl1" }, { "slug": "sgsm3", "symbol": "SGSM3", "hgnc": "HGNC:25228", "name": "small G protein signaling modulator 3", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/sgsm3" }, { "slug": "slc25a36", "symbol": "SLC25A36", "hgnc": "HGNC:25554", "name": "solute carrier family 25 member 36", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/slc25a36" }, { "slug": "sox17", "symbol": "SOX17", "hgnc": "HGNC:18122", "name": "SRY-box transcription factor 17", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/sox17" }, { "slug": "supt7l", "symbol": "SUPT7L", "hgnc": "HGNC:30632", "name": "SPT7 like, STAGA complex subunit gamma", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/supt7l" }, { "slug": "tg", "symbol": "TG", "hgnc": "HGNC:11764", "name": "thyroglobulin", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/tg" }, { "slug": "tpo", "symbol": "TPO", "hgnc": "HGNC:12015", "name": "thyroid peroxidase", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/tpo" }, { "slug": "tshb", "symbol": "TSHB", "hgnc": "HGNC:12372", "name": "thyroid stimulating hormone subunit beta", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/tshb" }, { "slug": "uggt1", "symbol": "UGGT1", "hgnc": "HGNC:15663", "name": "UDP-glucose glycoprotein glucosyltransferase 1", "frequency": "obligate", "diseases": 1, "url": "https://dantelabs.com/genes/uggt1" }, { "slug": "dcaf17", "symbol": "DCAF17", "hgnc": "HGNC:25784", "name": "DDB1 and CUL4 associated factor 17", "frequency": "very-frequent", "diseases": 2, "url": "https://dantelabs.com/genes/dcaf17" }, { "slug": "dna2", "symbol": "DNA2", "hgnc": "HGNC:2939", "name": "DNA replication helicase/nuclease 2", "frequency": "very-frequent", "diseases": 1, "url": "https://dantelabs.com/genes/dna2" }, { "slug": "fuca1", "symbol": "FUCA1", "hgnc": "HGNC:4006", "name": "alpha-L-fucosidase 1", "frequency": "very-frequent", "diseases": 1, "url": "https://dantelabs.com/genes/fuca1" }, { "slug": "kat6b", "symbol": "KAT6B", "hgnc": "HGNC:17582", "name": "lysine acetyltransferase 6B", "frequency": "very-frequent", "diseases": 3, "url": "https://dantelabs.com/genes/kat6b" }, { "slug": "nkx2-1", "symbol": "NKX2-1", "hgnc": "HGNC:11825", "name": "NK2 homeobox 1", "frequency": "very-frequent", "diseases": 1, "url": "https://dantelabs.com/genes/nkx2-1" }, { "slug": "pnpla6", "symbol": "PNPLA6", "hgnc": "HGNC:16268", "name": "patatin like domain 6, lysophospholipase", "frequency": "very-frequent", "diseases": 2, "url": "https://dantelabs.com/genes/pnpla6" }, { "slug": "slc26a4", "symbol": "SLC26A4", "hgnc": "HGNC:8818", "name": "solute carrier family 26 member 4", "frequency": "very-frequent", "diseases": 3, "url": "https://dantelabs.com/genes/slc26a4" }, { "slug": "tshr", "symbol": "TSHR", "hgnc": "HGNC:12373", "name": "thyroid stimulating hormone receptor", "frequency": "very-frequent", "diseases": 2, "url": "https://dantelabs.com/genes/tshr" }, { "slug": "adcy5", "symbol": "ADCY5", "hgnc": "HGNC:236", "name": "adenylate cyclase 5", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/adcy5" }, { "slug": "alg2", "symbol": "ALG2", "hgnc": "HGNC:23159", "name": "ALG2 alpha-1,3/1,6-mannosyltransferase", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/alg2" }, { "slug": "alg8", "symbol": "ALG8", "hgnc": "HGNC:23161", "name": "ALG8 alpha-1,3-glucosyltransferase", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/alg8" }, { "slug": "cblb", "symbol": "CBLB", "hgnc": "HGNC:1542", "name": "Cbl proto-oncogene B", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/cblb" }, { "slug": "ccdc47", "symbol": "CCDC47", "hgnc": "HGNC:24856", "name": "coiled-coil domain containing 47", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/ccdc47" }, { "slug": "cd274", "symbol": "CD274", "hgnc": "HGNC:17635", "name": "CD274 molecule", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/cd274" }, { "slug": "cdon", "symbol": "CDON", "hgnc": "HGNC:17104", "name": "cell adhesion associated, oncogene regulated", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/cdon" }, { "slug": "cep57", "symbol": "CEP57", "hgnc": "HGNC:30794", "name": "centrosomal protein 57", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/cep57" }, { "slug": "exosc2", "symbol": "EXOSC2", "hgnc": "HGNC:17097", "name": "exosome component 2", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/exosc2" }, { "slug": "foxi1", "symbol": "FOXI1", "hgnc": "HGNC:3815", "name": "forkhead box I1", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/foxi1" }, { "slug": "fut8", "symbol": "FUT8", "hgnc": "HGNC:4019", "name": "fucosyltransferase 8", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/fut8" }, { "slug": "gnas", "symbol": "GNAS", "hgnc": "HGNC:4392", "name": "GNAS complex locus", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/gnas" }, { "slug": "gne", "symbol": "GNE", "hgnc": "HGNC:23657", "name": "glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/gne" }, { "slug": "gpr161", "symbol": "GPR161", "hgnc": "HGNC:23694", "name": "G protein-coupled receptor 161", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/gpr161" }, { "slug": "hesx1", "symbol": "HESX1", "hgnc": "HGNC:4877", "name": "HESX homeobox 1", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/hesx1" }, { "slug": "itch", "symbol": "ITCH", "hgnc": "HGNC:13890", "name": "itchy E3 ubiquitin protein ligase", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/itch" }, { "slug": "kcnj10", "symbol": "KCNJ10", "hgnc": "HGNC:6256", "name": "potassium inwardly rectifying channel subfamily J member 10", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/kcnj10" }, { "slug": "klf1", "symbol": "KLF1", "hgnc": "HGNC:6345", "name": "KLF transcription factor 1", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/klf1" }, { "slug": "lhx4", "symbol": "LHX4", "hgnc": "HGNC:21734", "name": "LIM homeobox 4", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/lhx4" }, { "slug": "lig4", "symbol": "LIG4", "hgnc": "HGNC:6601", "name": "DNA ligase 4", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/lig4" }, { "slug": "mt-tl1", "symbol": "MT-TL1", "hgnc": "HGNC:7490", "name": "mitochondrially encoded tRNA-Leu (UUA/G) 1", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/mt-tl1" }, { "slug": "mt-tl2", "symbol": "MT-TL2", "hgnc": "HGNC:7491", "name": "mitochondrially encoded tRNA-Leu (CUN) 2", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/mt-tl2" }, { "slug": "mt-tn", "symbol": "MT-TN", "hgnc": "HGNC:7493", "name": "mitochondrially encoded tRNA-Asn (AAU/C)", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/mt-tn" }, { "slug": "mt-ts1", "symbol": "MT-TS1", "hgnc": "HGNC:7497", "name": "mitochondrially encoded tRNA-Ser (UCN) 1", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/mt-ts1" }, { "slug": "nr6a1", "symbol": "NR6A1", "hgnc": "HGNC:7985", "name": "nuclear receptor subfamily 6 group A member 1", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/nr6a1" }, { "slug": "pik3c2a", "symbol": "PIK3C2A", "hgnc": "HGNC:8971", "name": "phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/pik3c2a" }, { "slug": "polr3gl", "symbol": "POLR3GL", "hgnc": "HGNC:28466", "name": "RNA polymerase III subunit GL", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/polr3gl" }, { "slug": "prim1", "symbol": "PRIM1", "hgnc": "HGNC:9369", "name": "DNA primase subunit 1", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/prim1" }, { "slug": "prokr2", "symbol": "PROKR2", "hgnc": "HGNC:15836", "name": "prokineticin receptor 2", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/prokr2" }, { "slug": "rnu6atac", "symbol": "RNU6ATAC", "hgnc": "HGNC:34017", "name": "RNA, U6atac small nuclear", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/rnu6atac" }, { "slug": "rnu7-1", "symbol": "RNU7-1", "hgnc": "HGNC:34033", "name": "RNA, U7 small nuclear 1", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/rnu7-1" }, { "slug": "robo1", "symbol": "ROBO1", "hgnc": "HGNC:10249", "name": "roundabout guidance receptor 1", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/robo1" }, { "slug": "sash3", "symbol": "SASH3", "hgnc": "HGNC:15975", "name": "SAM and SH3 domain containing 3", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/sash3" }, { "slug": "spop", "symbol": "SPOP", "hgnc": "HGNC:11254", "name": "speckle type BTB/POZ protein", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/spop" }, { "slug": "tbck", "symbol": "TBCK", "hgnc": "HGNC:28261", "name": "TBC1 domain containing kinase", "frequency": "frequent", "diseases": 2, "url": "https://dantelabs.com/genes/tbck" }, { "slug": "tiam1", "symbol": "TIAM1", "hgnc": "HGNC:11805", "name": "TIAM Rac1 associated GEF 1", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/tiam1" }, { "slug": "ubr7", "symbol": "UBR7", "hgnc": "HGNC:20344", "name": "ubiquitin protein ligase E3 component n-recognin 7", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/ubr7" }, { "slug": "wdr11", "symbol": "WDR11", "hgnc": "HGNC:13831", "name": "WD repeat domain 11", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/wdr11" }, { "slug": "wdr4", "symbol": "WDR4", "hgnc": "HGNC:12756", "name": "WDR4 tRNA N7-guanosine methyltransferase non-catalytic subunit", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/wdr4" }, { "slug": "zbtb20", "symbol": "ZBTB20", "hgnc": "HGNC:13503", "name": "zinc finger and BTB domain containing 20", "frequency": "frequent", "diseases": 1, "url": "https://dantelabs.com/genes/zbtb20" }, { "slug": "abcc8", "symbol": "ABCC8", "hgnc": "HGNC:59", "name": "ATP binding cassette subfamily C member 8", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/abcc8" }, { "slug": "ada", "symbol": "ADA", "hgnc": "HGNC:186", "name": "adenosine deaminase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ada" }, { "slug": "adar", "symbol": "ADAR", "hgnc": "HGNC:225", "name": "adenosine deaminase RNA specific", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/adar" }, { "slug": "aff4", "symbol": "AFF4", "hgnc": "HGNC:17869", "name": "ALF transcription elongation factor 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/aff4" }, { "slug": "aire", "symbol": "AIRE", "hgnc": "HGNC:360", "name": "autoimmune regulator", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/aire" }, { "slug": "alx4", "symbol": "ALX4", "hgnc": "HGNC:450", "name": "ALX homeobox 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/alx4" }, { "slug": "anapc1", "symbol": "ANAPC1", "hgnc": "HGNC:19988", "name": "anaphase promoting complex subunit 1", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/anapc1" }, { "slug": "apc", "symbol": "APC", "hgnc": "HGNC:583", "name": "APC regulator of Wnt signaling pathway", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/apc" }, { "slug": "apoe", "symbol": "APOE", "hgnc": "HGNC:613", "name": "apolipoprotein E", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/apoe" }, { "slug": "arl6", "symbol": "ARL6", "hgnc": "HGNC:13210", "name": "ARF like GTPase 6", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/arl6" }, { "slug": "arl6ip6", "symbol": "ARL6IP6", "hgnc": "HGNC:24048", "name": "ARF like GTPase 6 interacting protein 6", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/arl6ip6" }, { "slug": "arvcf", "symbol": "ARVCF", "hgnc": "HGNC:728", "name": "ARVCF delta catenin family member", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/arvcf" }, { "slug": "ash1l", "symbol": "ASH1L", "hgnc": "HGNC:19088", "name": "ASH1 like histone lysine methyltransferase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ash1l" }, { "slug": "atp5f1a", "symbol": "ATP5F1A", "hgnc": "HGNC:823", "name": "ATP synthase F1 subunit alpha", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/atp5f1a" }, { "slug": "atp5f1d", "symbol": "ATP5F1D", "hgnc": "HGNC:837", "name": "ATP synthase F1 subunit delta", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/atp5f1d" }, { "slug": "atp5f1e", "symbol": "ATP5F1E", "hgnc": "HGNC:838", "name": "ATP synthase F1 subunit epsilon", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/atp5f1e" }, { "slug": "atp5mk", "symbol": "ATP5MK", "hgnc": "HGNC:30889", "name": "ATP synthase membrane subunit k", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/atp5mk" }, { "slug": "atp5po", "symbol": "ATP5PO", "hgnc": "HGNC:850", "name": "ATP synthase peripheral stalk subunit OSCP", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/atp5po" }, { "slug": "atpaf2", "symbol": "ATPAF2", "hgnc": "HGNC:18802", "name": "ATP synthase mitochondrial F1 complex assembly factor 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/atpaf2" }, { "slug": "b4galt1", "symbol": "B4GALT1", "hgnc": "HGNC:924", "name": "beta-1,4-galactosyltransferase 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/b4galt1" }, { "slug": "baz1b", "symbol": "BAZ1B", "hgnc": "HGNC:961", "name": "bromodomain adjacent to zinc finger domain 1B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/baz1b" }, { "slug": "bbip1", "symbol": "BBIP1", "hgnc": "HGNC:28093", "name": "BBSome interacting protein 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbip1" }, { "slug": "bbs1", "symbol": "BBS1", "hgnc": "HGNC:966", "name": "Bardet-Biedl syndrome 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs1" }, { "slug": "bbs10", "symbol": "BBS10", "hgnc": "HGNC:26291", "name": "Bardet-Biedl syndrome 10", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs10" }, { "slug": "bbs12", "symbol": "BBS12", "hgnc": "HGNC:26648", "name": "Bardet-Biedl syndrome 12", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs12" }, { "slug": "bbs2", "symbol": "BBS2", "hgnc": "HGNC:967", "name": "Bardet-Biedl syndrome 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs2" }, { "slug": "bbs4", "symbol": "BBS4", "hgnc": "HGNC:969", "name": "Bardet-Biedl syndrome 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs4" }, { "slug": "bbs5", "symbol": "BBS5", "hgnc": "HGNC:970", "name": "Bardet-Biedl syndrome 5", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs5" }, { "slug": "bbs7", "symbol": "BBS7", "hgnc": "HGNC:18758", "name": "Bardet-Biedl syndrome 7", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs7" }, { "slug": "bbs9", "symbol": "BBS9", "hgnc": "HGNC:30000", "name": "Bardet-Biedl syndrome 9", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bbs9" }, { "slug": "bcor", "symbol": "BCOR", "hgnc": "HGNC:20893", "name": "BCL6 corepressor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bcor" }, { "slug": "bicra", "symbol": "BICRA", "hgnc": "HGNC:4332", "name": "BRD4 interacting chromatin remodeling complex associated protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bicra" }, { "slug": "bmp6", "symbol": "BMP6", "hgnc": "HGNC:1073", "name": "bone morphogenetic protein 6", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bmp6" }, { "slug": "bub1", "symbol": "BUB1", "hgnc": "HGNC:1148", "name": "BUB1 mitotic checkpoint serine/threonine kinase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bub1" }, { "slug": "bub1b", "symbol": "BUB1B", "hgnc": "HGNC:1149", "name": "BUB1 mitotic checkpoint serine/threonine kinase B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bub1b" }, { "slug": "bub3", "symbol": "BUB3", "hgnc": "HGNC:1151", "name": "BUB3 mitotic checkpoint protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bub3" }, { "slug": "bud23", "symbol": "BUD23", "hgnc": "HGNC:16405", "name": "BUD23 rRNA methyltransferase and ribosome maturation factor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/bud23" }, { "slug": "c1qbp", "symbol": "C1QBP", "hgnc": "HGNC:1243", "name": "complement C1q binding protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/c1qbp" }, { "slug": "cacna1c", "symbol": "CACNA1C", "hgnc": "HGNC:1390", "name": "calcium voltage-gated channel subunit alpha1 C", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cacna1c" }, { "slug": "casz1", "symbol": "CASZ1", "hgnc": "HGNC:26002", "name": "castor zinc finger 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/casz1" }, { "slug": "cd4", "symbol": "CD4", "hgnc": "HGNC:1678", "name": "CD4 molecule", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cd4" }, { "slug": "cd55", "symbol": "CD55", "hgnc": "HGNC:2665", "name": "CD55 molecule (Cromer blood group)", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cd55" }, { "slug": "cdkn1c", "symbol": "CDKN1C", "hgnc": "HGNC:1786", "name": "cyclin dependent kinase inhibitor 1C", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cdkn1c" }, { "slug": "cep19", "symbol": "CEP19", "hgnc": "HGNC:28209", "name": "centrosomal protein 19", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cep19" }, { "slug": "cep290", "symbol": "CEP290", "hgnc": "HGNC:29021", "name": "centrosomal protein 290", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cep290" }, { "slug": "cfap418", "symbol": "CFAP418", "hgnc": "HGNC:27232", "name": "cilia and flagella associated protein 418", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cfap418" }, { "slug": "chd6", "symbol": "CHD6", "hgnc": "HGNC:19057", "name": "chromodomain helicase DNA binding protein 6", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/chd6" }, { "slug": "chd7", "symbol": "CHD7", "hgnc": "HGNC:20626", "name": "chromodomain helicase DNA binding protein 7", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/chd7" }, { "slug": "chd8", "symbol": "CHD8", "hgnc": "HGNC:20153", "name": "chromodomain helicase DNA binding protein 8", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/chd8" }, { "slug": "clip2", "symbol": "CLIP2", "hgnc": "HGNC:2586", "name": "CAP-Gly domain containing linker protein 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/clip2" }, { "slug": "clpb", "symbol": "CLPB", "hgnc": "HGNC:30664", "name": "ClpB family mitochondrial disaggregase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/clpb" }, { "slug": "comt", "symbol": "COMT", "hgnc": "HGNC:2228", "name": "catechol-O-methyltransferase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/comt" }, { "slug": "creld1", "symbol": "CRELD1", "hgnc": "HGNC:14630", "name": "CRELD disulfide isomerase 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/creld1" }, { "slug": "cripto", "symbol": "CRIPTO", "hgnc": "HGNC:11701", "name": "cripto, EGF-CFC family member", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cripto" }, { "slug": "ctns", "symbol": "CTNS", "hgnc": "HGNC:2518", "name": "cystinosin, lysosomal cystine transporter", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ctns" }, { "slug": "cyp27a1", "symbol": "CYP27A1", "hgnc": "HGNC:2605", "name": "cytochrome P450 family 27 subfamily A member 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/cyp27a1" }, { "slug": "dact1", "symbol": "DACT1", "hgnc": "HGNC:17748", "name": "dishevelled binding antagonist of beta catenin 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/dact1" }, { "slug": "dclre1c", "symbol": "DCLRE1C", "hgnc": "HGNC:17642", "name": "DNA cross-link repair 1C", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/dclre1c" }, { "slug": "ddb1", "symbol": "DDB1", "hgnc": "HGNC:2717", "name": "damage specific DNA binding protein 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ddb1" }, { "slug": "disp1", "symbol": "DISP1", "hgnc": "HGNC:19711", "name": "dispatched RND transporter family member 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/disp1" }, { "slug": "dll1", "symbol": "DLL1", "hgnc": "HGNC:2908", "name": "delta like canonical Notch ligand 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/dll1" }, { "slug": "dnajc30", "symbol": "DNAJC30", "hgnc": "HGNC:16410", "name": "DnaJ heat shock protein family (Hsp40) member C30", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/dnajc30" }, { "slug": "dot1l", "symbol": "DOT1L", "hgnc": "HGNC:24948", "name": "DOT1 like histone lysine methyltransferase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/dot1l" }, { "slug": "eif2ak3", "symbol": "EIF2AK3", "hgnc": "HGNC:3255", "name": "eukaryotic translation initiation factor 2 alpha kinase 3", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/eif2ak3" }, { "slug": "eif4h", "symbol": "EIF4H", "hgnc": "HGNC:12741", "name": "eukaryotic translation initiation factor 4H", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/eif4h" }, { "slug": "eln", "symbol": "ELN", "hgnc": "HGNC:3327", "name": "elastin", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/eln" }, { "slug": "ext2", "symbol": "EXT2", "hgnc": "HGNC:3513", "name": "exostosin glycosyltransferase 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ext2" }, { "slug": "fbxo22", "symbol": "FBXO22", "hgnc": "HGNC:13593", "name": "F-box protein 22", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/fbxo22" }, { "slug": "fgf13", "symbol": "FGF13", "hgnc": "HGNC:3670", "name": "fibroblast growth factor 13", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/fgf13" }, { "slug": "fgf8", "symbol": "FGF8", "hgnc": "HGNC:3686", "name": "fibroblast growth factor 8", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/fgf8" }, { "slug": "fgfr1", "symbol": "FGFR1", "hgnc": "HGNC:3688", "name": "fibroblast growth factor receptor 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/fgfr1" }, { "slug": "fkbp6", "symbol": "FKBP6", "hgnc": "HGNC:3722", "name": "FKBP prolyl isomerase family member 6 (inactive)", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/fkbp6" }, { "slug": "flcn", "symbol": "FLCN", "hgnc": "HGNC:27310", "name": "folliculin", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/flcn" }, { "slug": "fmr1", "symbol": "FMR1", "hgnc": "HGNC:3775", "name": "fragile X messenger ribonucleoprotein 1", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/fmr1" }, { "slug": "foxh1", "symbol": "FOXH1", "hgnc": "HGNC:3814", "name": "forkhead box H1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/foxh1" }, { "slug": "foxn1", "symbol": "FOXN1", "hgnc": "HGNC:12765", "name": "forkhead box N1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/foxn1" }, { "slug": "foxp1", "symbol": "FOXP1", "hgnc": "HGNC:3823", "name": "forkhead box P1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/foxp1" }, { "slug": "foxp3", "symbol": "FOXP3", "hgnc": "HGNC:6106", "name": "forkhead box P3", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/foxp3" }, { "slug": "gabrd", "symbol": "GABRD", "hgnc": "HGNC:4084", "name": "gamma-aminobutyric acid type A receptor subunit delta", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gabrd" }, { "slug": "gas1", "symbol": "GAS1", "hgnc": "HGNC:4165", "name": "growth arrest specific 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gas1" }, { "slug": "gch1", "symbol": "GCH1", "hgnc": "HGNC:4193", "name": "GTP cyclohydrolase 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gch1" }, { "slug": "gli2", "symbol": "GLI2", "hgnc": "HGNC:4318", "name": "GLI family zinc finger 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gli2" }, { "slug": "gna11", "symbol": "GNA11", "hgnc": "HGNC:4379", "name": "G protein subunit alpha 11", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gna11" }, { "slug": "gp1bb", "symbol": "GP1BB", "hgnc": "HGNC:4440", "name": "glycoprotein Ib platelet subunit beta", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gp1bb" }, { "slug": "gria1", "symbol": "GRIA1", "hgnc": "HGNC:4571", "name": "glutamate ionotropic receptor AMPA type subunit 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gria1" }, { "slug": "grin2b", "symbol": "GRIN2B", "hgnc": "HGNC:4586", "name": "glutamate ionotropic receptor NMDA type subunit 2B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/grin2b" }, { "slug": "grm7", "symbol": "GRM7", "hgnc": "HGNC:4599", "name": "glutamate metabotropic receptor 7", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/grm7" }, { "slug": "gtf2i", "symbol": "GTF2I", "hgnc": "HGNC:4659", "name": "general transcription factor IIi", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gtf2i" }, { "slug": "gtf2ird1", "symbol": "GTF2IRD1", "hgnc": "HGNC:4661", "name": "GTF2I repeat domain containing 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gtf2ird1" }, { "slug": "gtf2ird2", "symbol": "GTF2IRD2", "hgnc": "HGNC:30775", "name": "GTF2I repeat domain containing 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/gtf2ird2" }, { "slug": "hbb", "symbol": "HBB", "hgnc": "HGNC:4827", "name": "hemoglobin subunit beta", "frequency": "occasional", "diseases": 3, "url": "https://dantelabs.com/genes/hbb" }, { "slug": "hdac4", "symbol": "HDAC4", "hgnc": "HGNC:14063", "name": "histone deacetylase 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hdac4" }, { "slug": "hfe", "symbol": "HFE", "hgnc": "HGNC:4886", "name": "homeostatic iron regulator", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hfe" }, { "slug": "hgd", "symbol": "HGD", "hgnc": "HGNC:4892", "name": "homogentisate 1,2-dioxygenase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hgd" }, { "slug": "hira", "symbol": "HIRA", "hgnc": "HGNC:4916", "name": "histone cell cycle regulator", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hira" }, { "slug": "hmga2", "symbol": "HMGA2", "hgnc": "HGNC:5009", "name": "high mobility group AT-hook 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hmga2" }, { "slug": "hnf1b", "symbol": "HNF1B", "hgnc": "HGNC:11630", "name": "HNF1 homeobox B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hnf1b" }, { "slug": "hnrnpk", "symbol": "HNRNPK", "hgnc": "HGNC:5044", "name": "heterogeneous nuclear ribonucleoprotein K", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/hnrnpk" }, { "slug": "hpd", "symbol": "HPD", "hgnc": "HGNC:5147", "name": "4-hydroxyphenylpyruvate dioxygenase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hpd" }, { "slug": "hspg2", "symbol": "HSPG2", "hgnc": "HGNC:5273", "name": "heparan sulfate proteoglycan 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hspg2" }, { "slug": "hymai", "symbol": "HYMAI", "hgnc": "HGNC:5326", "name": "hydatidiform mole associated and imprinted", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/hymai" }, { "slug": "ifih1", "symbol": "IFIH1", "hgnc": "HGNC:18873", "name": "interferon induced with helicase C domain 1", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/ifih1" }, { "slug": "ift172", "symbol": "IFT172", "hgnc": "HGNC:30391", "name": "intraflagellar transport 172", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ift172" }, { "slug": "ift27", "symbol": "IFT27", "hgnc": "HGNC:18626", "name": "intraflagellar transport 27", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ift27" }, { "slug": "ift74", "symbol": "IFT74", "hgnc": "HGNC:21424", "name": "intraflagellar transport 74", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ift74" }, { "slug": "igf2", "symbol": "IGF2", "hgnc": "HGNC:5466", "name": "insulin like growth factor 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/igf2" }, { "slug": "il2rg", "symbol": "IL2RG", "hgnc": "HGNC:6010", "name": "interleukin 2 receptor subunit gamma", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/il2rg" }, { "slug": "il7r", "symbol": "IL7R", "hgnc": "HGNC:6024", "name": "interleukin 7 receptor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/il7r" }, { "slug": "impdh2", "symbol": "IMPDH2", "hgnc": "HGNC:6053", "name": "inosine monophosphate dehydrogenase 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/impdh2" }, { "slug": "insr", "symbol": "INSR", "hgnc": "HGNC:6091", "name": "insulin receptor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/insr" }, { "slug": "ipo8", "symbol": "IPO8", "hgnc": "HGNC:9853", "name": "importin 8", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ipo8" }, { "slug": "irf4", "symbol": "IRF4", "hgnc": "HGNC:6119", "name": "interferon regulatory factor 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/irf4" }, { "slug": "jmjd1c", "symbol": "JMJD1C", "hgnc": "HGNC:12313", "name": "jumonji domain containing 1C", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/jmjd1c" }, { "slug": "kcnab2", "symbol": "KCNAB2", "hgnc": "HGNC:6229", "name": "potassium voltage-gated channel subfamily A regulatory beta subunit 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/kcnab2" }, { "slug": "kcnj11", "symbol": "KCNJ11", "hgnc": "HGNC:6257", "name": "potassium inwardly rectifying channel subfamily J member 11", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/kcnj11" }, { "slug": "kiss1r", "symbol": "KISS1R", "hgnc": "HGNC:4510", "name": "KISS1 receptor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/kiss1r" }, { "slug": "kmt2b", "symbol": "KMT2B", "hgnc": "HGNC:15840", "name": "lysine methyltransferase 2B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/kmt2b" }, { "slug": "lifr", "symbol": "LIFR", "hgnc": "HGNC:6597", "name": "LIF receptor subunit alpha", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/lifr" }, { "slug": "limk1", "symbol": "LIMK1", "hgnc": "HGNC:6613", "name": "LIM domain kinase 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/limk1" }, { "slug": "lrba", "symbol": "LRBA", "hgnc": "HGNC:1742", "name": "LPS responsive beige-like anchor protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/lrba" }, { "slug": "lrp4", "symbol": "LRP4", "hgnc": "HGNC:6696", "name": "LDL receptor related protein 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/lrp4" }, { "slug": "lsm11", "symbol": "LSM11", "hgnc": "HGNC:30860", "name": "LSM11, U7 small nuclear RNA associated", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/lsm11" }, { "slug": "luzp1", "symbol": "LUZP1", "hgnc": "HGNC:14985", "name": "leucine zipper protein 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/luzp1" }, { "slug": "lztfl1", "symbol": "LZTFL1", "hgnc": "HGNC:6741", "name": "leucine zipper transcription factor like 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/lztfl1" }, { "slug": "mdm4", "symbol": "MDM4", "hgnc": "HGNC:6974", "name": "MDM4 regulator of p53", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mdm4" }, { "slug": "mettl27", "symbol": "METTL27", "hgnc": "HGNC:19068", "name": "methyltransferase like 27", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mettl27" }, { "slug": "mkks", "symbol": "MKKS", "hgnc": "HGNC:7108", "name": "MKKS centrosomal shuttling protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mkks" }, { "slug": "mks1", "symbol": "MKS1", "hgnc": "HGNC:7121", "name": "MKS transition zone complex subunit 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mks1" }, { "slug": "mlxipl", "symbol": "MLXIPL", "hgnc": "HGNC:12744", "name": "MLX interacting protein like", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mlxipl" }, { "slug": "mmp23b", "symbol": "MMP23B", "hgnc": "HGNC:7171", "name": "matrix metallopeptidase 23B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mmp23b" }, { "slug": "mogs", "symbol": "MOGS", "hgnc": "HGNC:24862", "name": "mannosyl-oligosaccharide glucosidase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mogs" }, { "slug": "mpi", "symbol": "MPI", "hgnc": "HGNC:7216", "name": "mannose phosphate isomerase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mpi" }, { "slug": "mpv17", "symbol": "MPV17", "hgnc": "HGNC:7224", "name": "mitochondrial inner membrane protein MPV17", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mpv17" }, { "slug": "mt-atp6", "symbol": "MT-ATP6", "hgnc": "HGNC:7414", "name": "mitochondrially encoded ATP synthase membrane subunit 6", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mt-atp6" }, { "slug": "mt-atp8", "symbol": "MT-ATP8", "hgnc": "HGNC:7415", "name": "mitochondrially encoded ATP synthase membrane subunit 8", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/mt-atp8" }, { "slug": "ncf1", "symbol": "NCF1", "hgnc": "HGNC:7660", "name": "neutrophil cytosolic factor 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ncf1" }, { "slug": "nodal", "symbol": "NODAL", "hgnc": "HGNC:7865", "name": "nodal growth differentiation factor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/nodal" }, { "slug": "nphp1", "symbol": "NPHP1", "hgnc": "HGNC:7905", "name": "nephrocystin 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/nphp1" }, { "slug": "nr4a2", "symbol": "NR4A2", "hgnc": "HGNC:7981", "name": "nuclear receptor subfamily 4 group A member 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/nr4a2" }, { "slug": "nudcd3", "symbol": "NUDCD3", "hgnc": "HGNC:22208", "name": "NudC domain containing 3", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/nudcd3" }, { "slug": "pdpn", "symbol": "PDPN", "hgnc": "HGNC:29602", "name": "podoplanin", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/pdpn" }, { "slug": "phf21a", "symbol": "PHF21A", "hgnc": "HGNC:24156", "name": "PHD finger protein 21A", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/phf21a" }, { "slug": "plaat3", "symbol": "PLAAT3", "hgnc": "HGNC:17825", "name": "phospholipase A and acyltransferase 3", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/plaat3" }, { "slug": "plag1", "symbol": "PLAG1", "hgnc": "HGNC:9045", "name": "PLAG1 zinc finger", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/plag1" }, { "slug": "plagl1", "symbol": "PLAGL1", "hgnc": "HGNC:9046", "name": "PLAG1 like zinc finger 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/plagl1" }, { "slug": "ppp1r15b", "symbol": "PPP1R15B", "hgnc": "HGNC:14951", "name": "protein phosphatase 1 regulatory subunit 15B", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/ppp1r15b" }, { "slug": "prdm16", "symbol": "PRDM16", "hgnc": "HGNC:14000", "name": "PR/SET domain 16", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/prdm16" }, { "slug": "prkcz", "symbol": "PRKCZ", "hgnc": "HGNC:9412", "name": "protein kinase C zeta", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/prkcz" }, { "slug": "psmb10", "symbol": "PSMB10", "hgnc": "HGNC:9538", "name": "proteasome 20S subunit beta 10", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/psmb10" }, { "slug": "ptch1", "symbol": "PTCH1", "hgnc": "HGNC:9585", "name": "patched 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ptch1" }, { "slug": "rag1", "symbol": "RAG1", "hgnc": "HGNC:9831", "name": "recombination activating 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rag1" }, { "slug": "rag2", "symbol": "RAG2", "hgnc": "HGNC:9832", "name": "recombination activating 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rag2" }, { "slug": "rai1", "symbol": "RAI1", "hgnc": "HGNC:9834", "name": "retinoic acid induced 1", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/rai1" }, { "slug": "rere", "symbol": "RERE", "hgnc": "HGNC:9965", "name": "arginine-glutamic acid dipeptide repeats", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rere" }, { "slug": "rfc2", "symbol": "RFC2", "hgnc": "HGNC:9970", "name": "replication factor C subunit 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rfc2" }, { "slug": "rmrp", "symbol": "RMRP", "hgnc": "HGNC:10031", "name": "RNA component of mitochondrial RNA processing endoribonuclease", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rmrp" }, { "slug": "rnaseh2a", "symbol": "RNASEH2A", "hgnc": "HGNC:18518", "name": "ribonuclease H2 subunit A", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rnaseh2a" }, { "slug": "rnaseh2b", "symbol": "RNASEH2B", "hgnc": "HGNC:25671", "name": "ribonuclease H2 subunit B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rnaseh2b" }, { "slug": "rnaseh2c", "symbol": "RNASEH2C", "hgnc": "HGNC:24116", "name": "ribonuclease H2 subunit C", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rnaseh2c" }, { "slug": "rnu4-2", "symbol": "RNU4-2", "hgnc": "HGNC:10193", "name": "RNA, U4 small nuclear 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rnu4-2" }, { "slug": "rreb1", "symbol": "RREB1", "hgnc": "HGNC:10449", "name": "ras responsive element binding protein 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/rreb1" }, { "slug": "sall1", "symbol": "SALL1", "hgnc": "HGNC:10524", "name": "spalt like transcription factor 1", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/sall1" }, { "slug": "samhd1", "symbol": "SAMHD1", "hgnc": "HGNC:15925", "name": "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/samhd1" }, { "slug": "scaper", "symbol": "SCAPER", "hgnc": "HGNC:13081", "name": "S-phase cyclin A associated protein in the ER", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/scaper" }, { "slug": "sclt1", "symbol": "SCLT1", "hgnc": "HGNC:26406", "name": "sodium channel and clathrin linker 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/sclt1" }, { "slug": "scn4a", "symbol": "SCN4A", "hgnc": "HGNC:10591", "name": "sodium voltage-gated channel alpha subunit 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/scn4a" }, { "slug": "sdccag8", "symbol": "SDCCAG8", "hgnc": "HGNC:10671", "name": "SHH signaling and ciliogenesis regulator SDCCAG8", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/sdccag8" }, { "slug": "sec24c", "symbol": "SEC24C", "hgnc": "HGNC:10705", "name": "SEC24 homolog C, COPII component", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/sec24c" }, { "slug": "shh", "symbol": "SHH", "hgnc": "HGNC:10848", "name": "sonic hedgehog signaling molecule", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/shh" }, { "slug": "six3", "symbol": "SIX3", "hgnc": "HGNC:10889", "name": "SIX homeobox 3", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/six3" }, { "slug": "ski", "symbol": "SKI", "hgnc": "HGNC:10896", "name": "SKI proto-oncogene", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ski" }, { "slug": "slc37a4", "symbol": "SLC37A4", "hgnc": "HGNC:4061", "name": "solute carrier family 37 member 4", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/slc37a4" }, { "slug": "slc6a17", "symbol": "SLC6A17", "hgnc": "HGNC:31399", "name": "solute carrier family 6 member 17", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/slc6a17" }, { "slug": "slf2", "symbol": "SLF2", "hgnc": "HGNC:17814", "name": "SMC5/6 complex localization factor 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/slf2" }, { "slug": "spen", "symbol": "SPEN", "hgnc": "HGNC:17575", "name": "spen family transcriptional repressor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/spen" }, { "slug": "srd5a3", "symbol": "SRD5A3", "hgnc": "HGNC:25812", "name": "steroid 5 alpha-reductase 3", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/srd5a3" }, { "slug": "sry", "symbol": "SRY", "hgnc": "HGNC:11311", "name": "sex determining region Y", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/sry" }, { "slug": "stat1", "symbol": "STAT1", "hgnc": "HGNC:11362", "name": "signal transducer and activator of transcription 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/stat1" }, { "slug": "stat3", "symbol": "STAT3", "hgnc": "HGNC:11364", "name": "signal transducer and activator of transcription 3", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/stat3" }, { "slug": "steap3", "symbol": "STEAP3", "hgnc": "HGNC:24592", "name": "STEAP3 metalloreductase", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/steap3" }, { "slug": "stx1a", "symbol": "STX1A", "hgnc": "HGNC:11433", "name": "syntaxin 1A", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/stx1a" }, { "slug": "sufu", "symbol": "SUFU", "hgnc": "HGNC:16466", "name": "SUFU negative regulator of hedgehog signaling", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/sufu" }, { "slug": "supt16h", "symbol": "SUPT16H", "hgnc": "HGNC:11465", "name": "SPT16 homolog, facilitates chromatin remodeling subunit", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/supt16h" }, { "slug": "svbp", "symbol": "SVBP", "hgnc": "HGNC:29204", "name": "small vasohibin binding protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/svbp" }, { "slug": "tbl2", "symbol": "TBL2", "hgnc": "HGNC:11586", "name": "transducin beta like 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/tbl2" }, { "slug": "tbx1", "symbol": "TBX1", "hgnc": "HGNC:11592", "name": "T-box transcription factor 1", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/tbx1" }, { "slug": "tf", "symbol": "TF", "hgnc": "HGNC:11740", "name": "transferrin", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/tf" }, { "slug": "tgif1", "symbol": "TGIF1", "hgnc": "HGNC:11776", "name": "TGFB induced factor homeobox 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/tgif1" }, { "slug": "tmem270", "symbol": "TMEM270", "hgnc": "HGNC:23018", "name": "transmembrane protein 270", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/tmem270" }, { "slug": "tonsl", "symbol": "TONSL", "hgnc": "HGNC:7801", "name": "tonsoku like, DNA repair protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/tonsl" }, { "slug": "trex1", "symbol": "TREX1", "hgnc": "HGNC:12269", "name": "three prime repair exonuclease 1", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/trex1" }, { "slug": "trim32", "symbol": "TRIM32", "hgnc": "HGNC:16380", "name": "tripartite motif containing 32", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/trim32" }, { "slug": "trip13", "symbol": "TRIP13", "hgnc": "HGNC:12307", "name": "thyroid hormone receptor interactor 13", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/trip13" }, { "slug": "trmt10a", "symbol": "TRMT10A", "hgnc": "HGNC:28403", "name": "tRNA methyltransferase 10A", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/trmt10a" }, { "slug": "ttc8", "symbol": "TTC8", "hgnc": "HGNC:20087", "name": "tetratricopeptide repeat domain 8", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ttc8" }, { "slug": "ube4b", "symbol": "UBE4B", "hgnc": "HGNC:12500", "name": "ubiquitination factor E4B", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ube4b" }, { "slug": "ufd1", "symbol": "UFD1", "hgnc": "HGNC:12520", "name": "ubiquitin recognition factor in ER associated degradation 1", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/ufd1" }, { "slug": "vipas39", "symbol": "VIPAS39", "hgnc": "HGNC:20347", "name": "VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/vipas39" }, { "slug": "vps33b", "symbol": "VPS33B", "hgnc": "HGNC:12712", "name": "VPS33B late endosome and lysosome associated", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/vps33b" }, { "slug": "vps37d", "symbol": "VPS37D", "hgnc": "HGNC:18287", "name": "VPS37D subunit of ESCRT-I", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/vps37d" }, { "slug": "wdpcp", "symbol": "WDPCP", "hgnc": "HGNC:28027", "name": "WD repeat containing planar cell polarity effector", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/wdpcp" }, { "slug": "wfs1", "symbol": "WFS1", "hgnc": "HGNC:12762", "name": "wolframin ER transmembrane glycoprotein", "frequency": "occasional", "diseases": 2, "url": "https://dantelabs.com/genes/wfs1" }, { "slug": "yy1", "symbol": "YY1", "hgnc": "HGNC:12856", "name": "YY1 transcription factor", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/yy1" }, { "slug": "zfp57", "symbol": "ZFP57", "hgnc": "HGNC:18791", "name": "ZFP57 zinc finger protein", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/zfp57" }, { "slug": "zfx", "symbol": "ZFX", "hgnc": "HGNC:12869", "name": "zinc finger protein X-linked", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/zfx" }, { "slug": "zic2", "symbol": "ZIC2", "hgnc": "HGNC:12873", "name": "Zic family zinc finger 2", "frequency": "occasional", "diseases": 1, "url": "https://dantelabs.com/genes/zic2" }, { "slug": "abcb11", "symbol": "ABCB11", "hgnc": "HGNC:42", "name": "ATP binding cassette subfamily B member 11", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/abcb11" }, { "slug": "abcb4", "symbol": "ABCB4", "hgnc": "HGNC:45", "name": "ATP binding cassette subfamily B member 4", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/abcb4" }, { "slug": "acp5", "symbol": "ACP5", "hgnc": "HGNC:124", "name": "acid phosphatase 5, tartrate resistant", "frequency": "very-rare", "diseases": 2, "url": "https://dantelabs.com/genes/acp5" }, { "slug": "adamtsl2", "symbol": "ADAMTSL2", "hgnc": "HGNC:14631", "name": "ADAMTS like 2", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/adamtsl2" }, { "slug": "adat3", "symbol": "ADAT3", "hgnc": "HGNC:25151", "name": "adenosine deaminase tRNA specific 3", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/adat3" }, { "slug": "apc2", "symbol": "APC2", "hgnc": "HGNC:24036", "name": "APC regulator of Wnt signaling pathway 2", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/apc2" }, { "slug": "atp8b1", "symbol": "ATP8B1", "hgnc": "HGNC:3706", "name": "ATPase phospholipid transporting 8B1", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/atp8b1" }, { "slug": "btnl2", "symbol": "BTNL2", "hgnc": "HGNC:1142", "name": "butyrophilin like 2", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/btnl2" }, { "slug": "dnajc19", "symbol": "DNAJC19", "hgnc": "HGNC:30528", "name": "DnaJ heat shock protein family (Hsp40) member C19", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/dnajc19" }, { "slug": "dnm1l", "symbol": "DNM1L", "hgnc": "HGNC:2973", "name": "dynamin 1L", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/dnm1l" }, { "slug": "dyrk1a", "symbol": "DYRK1A", "hgnc": "HGNC:3091", "name": "dual specificity tyrosine phosphorylation regulated kinase 1A", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/dyrk1a" }, { "slug": "fbn1", "symbol": "FBN1", "hgnc": "HGNC:3603", "name": "fibrillin 1", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/fbn1" }, { "slug": "fdx2", "symbol": "FDX2", "hgnc": "HGNC:30546", "name": "ferredoxin 2", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/fdx2" }, { "slug": "hla-drb1", "symbol": "HLA-DRB1", "hgnc": "HGNC:4948", "name": "major histocompatibility complex, class II, DR beta 1", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/hla-drb1" }, { "slug": "ltbp3", "symbol": "LTBP3", "hgnc": "HGNC:6716", "name": "latent transforming growth factor beta binding protein 3", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/ltbp3" }, { "slug": "mt-co1", "symbol": "MT-CO1", "hgnc": "HGNC:7419", "name": "mitochondrially encoded cytochrome c oxidase I", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-co1" }, { "slug": "mt-co2", "symbol": "MT-CO2", "hgnc": "HGNC:7421", "name": "mitochondrially encoded cytochrome c oxidase II", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-co2" }, { "slug": "mt-co3", "symbol": "MT-CO3", "hgnc": "HGNC:7422", "name": "mitochondrially encoded cytochrome c oxidase III", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-co3" }, { "slug": "mt-nd1", "symbol": "MT-ND1", "hgnc": "HGNC:7455", "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-nd1" }, { "slug": "mt-nd4", "symbol": "MT-ND4", "hgnc": "HGNC:7459", "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-nd4" }, { "slug": "mt-nd5", "symbol": "MT-ND5", "hgnc": "HGNC:7461", "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-nd5" }, { "slug": "mt-nd6", "symbol": "MT-ND6", "hgnc": "HGNC:7462", "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-nd6" }, { "slug": "mt-tf", "symbol": "MT-TF", "hgnc": "HGNC:7481", "name": "mitochondrially encoded tRNA-Phe (UUU/C)", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-tf" }, { "slug": "mt-th", "symbol": "MT-TH", "hgnc": "HGNC:7487", "name": "mitochondrially encoded tRNA-His (CAU/C)", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-th" }, { "slug": "mt-tq", "symbol": "MT-TQ", "hgnc": "HGNC:7495", "name": "mitochondrially encoded tRNA-Gln (CAA/G)", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-tq" }, { "slug": "mt-ts2", "symbol": "MT-TS2", "hgnc": "HGNC:7498", "name": "mitochondrially encoded tRNA-Ser (AGU/C) 2", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-ts2" }, { "slug": "mt-tw", "symbol": "MT-TW", "hgnc": "HGNC:7501", "name": "mitochondrially encoded tRNA-Trp (UGA/G)", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mt-tw" }, { "slug": "mttp", "symbol": "MTTP", "hgnc": "HGNC:7467", "name": "microsomal triglyceride transfer protein", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/mttp" }, { "slug": "nr1h4", "symbol": "NR1H4", "hgnc": "HGNC:7967", "name": "nuclear receptor subfamily 1 group H member 4", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/nr1h4" }, { "slug": "nsd1", "symbol": "NSD1", "hgnc": "HGNC:14234", "name": "nuclear receptor binding SET domain protein 1", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/nsd1" }, { "slug": "opa1", "symbol": "OPA1", "hgnc": "HGNC:8140", "name": "OPA1 mitochondrial dynamin like GTPase", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/opa1" }, { "slug": "polg", "symbol": "POLG", "hgnc": "HGNC:9179", "name": "DNA polymerase gamma, catalytic subunit", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/polg" }, { "slug": "polg2", "symbol": "POLG2", "hgnc": "HGNC:9180", "name": "DNA polymerase gamma 2, accessory subunit", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/polg2" }, { "slug": "ppib", "symbol": "PPIB", "hgnc": "HGNC:9255", "name": "peptidylprolyl isomerase B", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/ppib" }, { "slug": "rrm2b", "symbol": "RRM2B", "hgnc": "HGNC:17296", "name": "ribonucleotide reductase regulatory TP53 inducible subunit M2B", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/rrm2b" }, { "slug": "saa1", "symbol": "SAA1", "hgnc": "HGNC:10513", "name": "serum amyloid A1", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/saa1" }, { "slug": "skic2", "symbol": "SKIC2", "hgnc": "HGNC:10898", "name": "SKI2 subunit of superkiller complex", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/skic2" }, { "slug": "skic3", "symbol": "SKIC3", "hgnc": "HGNC:23639", "name": "SKI3 subunit of superkiller complex", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/skic3" }, { "slug": "slc25a4", "symbol": "SLC25A4", "hgnc": "HGNC:10990", "name": "solute carrier family 25 member 4", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/slc25a4" }, { "slug": "stub1", "symbol": "STUB1", "hgnc": "HGNC:11427", "name": "STIP1 homology and U-box containing protein 1", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/stub1" }, { "slug": "twnk", "symbol": "TWNK", "hgnc": "HGNC:1160", "name": "twinkle mtDNA helicase", "frequency": "very-rare", "diseases": 1, "url": "https://dantelabs.com/genes/twnk" }, { "slug": "alms1", "symbol": "ALMS1", "hgnc": "HGNC:428", "name": "ALMS1 centrosome and basal body associated protein", "diseases": 1, "url": "https://dantelabs.com/genes/alms1" }, { "slug": "bmp4", "symbol": "BMP4", "hgnc": "HGNC:1071", "name": "bone morphogenetic protein 4", "diseases": 1, "url": "https://dantelabs.com/genes/bmp4" }, { "slug": "duox2", "symbol": "DUOX2", "hgnc": "HGNC:13273", "name": "dual oxidase 2", "diseases": 1, "url": "https://dantelabs.com/genes/duox2" }, { "slug": "duoxa2", "symbol": "DUOXA2", "hgnc": "HGNC:32698", "name": "dual oxidase maturation factor 2", "diseases": 1, "url": "https://dantelabs.com/genes/duoxa2" }, { "slug": "gyg1", "symbol": "GYG1", "hgnc": "HGNC:4699", "name": "glycogenin 1", "diseases": 1, "url": "https://dantelabs.com/genes/gyg1" }, { "slug": "hsd17b3", "symbol": "HSD17B3", "hgnc": "HGNC:5212", "name": "hydroxysteroid 17-beta dehydrogenase 3", "diseases": 1, "url": "https://dantelabs.com/genes/hsd17b3" }, { "slug": "ifng", "symbol": "IFNG", "hgnc": "HGNC:5438", "name": "interferon gamma", "diseases": 1, "url": "https://dantelabs.com/genes/ifng" }, { "slug": "iyd", "symbol": "IYD", "hgnc": "HGNC:21071", "name": "iodotyrosine deiodinase", "diseases": 1, "url": "https://dantelabs.com/genes/iyd" }, { "slug": "jak1", "symbol": "JAK1", "hgnc": "HGNC:6190", "name": "Janus kinase 1", "diseases": 1, "url": "https://dantelabs.com/genes/jak1" }, { "slug": "mcm8", "symbol": "MCM8", "hgnc": "HGNC:16147", "name": "minichromosome maintenance 8 homologous recombination repair factor", "diseases": 1, "url": "https://dantelabs.com/genes/mcm8" }, { "slug": "nphs1", "symbol": "NPHS1", "hgnc": "HGNC:7908", "name": "NPHS1 adhesion molecule, nephrin", "diseases": 1, "url": "https://dantelabs.com/genes/nphs1" }, { "slug": "piezo1", "symbol": "PIEZO1", "hgnc": "HGNC:28993", "name": "piezo type mechanosensitive ion channel component 1 (Er blood group)", "diseases": 1, "url": "https://dantelabs.com/genes/piezo1" }, { "slug": "pik3ca", "symbol": "PIK3CA", "hgnc": "HGNC:8975", "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha", "diseases": 1, "url": "https://dantelabs.com/genes/pik3ca" }, { "slug": "plvap", "symbol": "PLVAP", "hgnc": "HGNC:13635", "name": "plasmalemma vesicle associated protein", "diseases": 1, "url": "https://dantelabs.com/genes/plvap" }, { "slug": "pmm2", "symbol": "PMM2", "hgnc": "HGNC:9115", "name": "phosphomannomutase 2", "diseases": 1, "url": "https://dantelabs.com/genes/pmm2" }, { "slug": "prop1", "symbol": "PROP1", "hgnc": "HGNC:9455", "name": "PROP paired-like homeobox 1", "diseases": 1, "url": "https://dantelabs.com/genes/prop1" }, { "slug": "pten", "symbol": "PTEN", "hgnc": "HGNC:9588", "name": "phosphatase and tensin homolog", "diseases": 1, "url": "https://dantelabs.com/genes/pten" }, { "slug": "slc16a2", "symbol": "SLC16A2", "hgnc": "HGNC:10923", "name": "solute carrier family 16 member 2", "diseases": 1, "url": "https://dantelabs.com/genes/slc16a2" }, { "slug": "slc5a5", "symbol": "SLC5A5", "hgnc": "HGNC:11040", "name": "solute carrier family 5 member 5", "diseases": 1, "url": "https://dantelabs.com/genes/slc5a5" }, { "slug": "sox3", "symbol": "SOX3", "hgnc": "HGNC:11199", "name": "SRY-box transcription factor 3", "diseases": 1, "url": "https://dantelabs.com/genes/sox3" }, { "slug": "tango2", "symbol": "TANGO2", "hgnc": "HGNC:25439", "name": "transport and golgi organization 2 homolog", "diseases": 1, "url": "https://dantelabs.com/genes/tango2" }, { "slug": "tsc1", "symbol": "TSC1", "hgnc": "HGNC:12362", "name": "TSC complex subunit 1", "diseases": 1, "url": "https://dantelabs.com/genes/tsc1" }, { "slug": "tsc2", "symbol": "TSC2", "hgnc": "HGNC:12363", "name": "TSC complex subunit 2", "diseases": 1, "url": "https://dantelabs.com/genes/tsc2" }, { "slug": "ubr1", "symbol": "UBR1", "hgnc": "HGNC:16808", "name": "ubiquitin protein ligase E3 component n-recognin 1", "diseases": 1, "url": "https://dantelabs.com/genes/ubr1" }, { "slug": "xrcc4", "symbol": "XRCC4", "hgnc": "HGNC:12831", "name": "X-ray repair cross complementing 4", "diseases": 1, "url": "https://dantelabs.com/genes/xrcc4" } ] } }