{
  "url": "https://dantelabs.com/traits/heterotaxy",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "heterotaxy",
    "id": "HP:0030853",
    "name": "Heterotaxy",
    "definition": "An abnormality in which the internal thoraco-abdominal organs demonstrate abnormal arrangement across the left-right axis of the body.",
    "synonyms": [
      "Heterotaxia"
    ],
    "systems": [
      {
        "slug": "growth-abnormality",
        "name": "Growth abnormality",
        "url": "https://dantelabs.com/traits/growth-abnormality"
      }
    ],
    "broader": [
      {
        "slug": "growth-abnormality",
        "name": "Growth abnormality",
        "url": "https://dantelabs.com/traits/growth-abnormality"
      }
    ],
    "narrower": [
      {
        "slug": "isomerism",
        "name": "Isomerism",
        "genes": 3,
        "url": "https://dantelabs.com/traits/isomerism"
      },
      {
        "slug": "abnormality-of-abdominal-situs",
        "name": "Abnormality of abdominal situs",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormality-of-abdominal-situs"
      }
    ],
    "genes": [
      {
        "slug": "ccdc39",
        "symbol": "CCDC39",
        "hgnc": "HGNC:25244",
        "name": "coiled-coil domain 39 molecular ruler complex subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc39"
      },
      {
        "slug": "kdm3b",
        "symbol": "KDM3B",
        "hgnc": "HGNC:1337",
        "name": "lysine demethylase 3B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm3b"
      },
      {
        "slug": "mmp21",
        "symbol": "MMP21",
        "hgnc": "HGNC:14357",
        "name": "matrix metallopeptidase 21",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmp21"
      }
    ]
  }
}