{
  "url": "https://dantelabs.com/traits/diffuse-skin-atrophy",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "diffuse-skin-atrophy",
    "id": "HP:0007488",
    "name": "Diffuse skin atrophy",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "dermal-atrophy",
        "name": "Skin degeneration",
        "url": "https://dantelabs.com/traits/dermal-atrophy"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "porcn",
        "symbol": "PORCN",
        "hgnc": "HGNC:17652",
        "name": "porcupine O-acyltransferase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/porcn"
      },
      {
        "slug": "cd28",
        "symbol": "CD28",
        "hgnc": "HGNC:1653",
        "name": "CD28 molecule",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd28"
      },
      {
        "slug": "ctla4",
        "symbol": "CTLA4",
        "hgnc": "HGNC:2505",
        "name": "cytotoxic T-lymphocyte associated protein 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctla4"
      },
      {
        "slug": "gsn",
        "symbol": "GSN",
        "hgnc": "HGNC:4620",
        "name": "gelsolin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gsn"
      },
      {
        "slug": "tnfrsf1b",
        "symbol": "TNFRSF1B",
        "hgnc": "HGNC:11917",
        "name": "TNF receptor superfamily member 1B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfrsf1b"
      },
      {
        "slug": "fermt1",
        "symbol": "FERMT1",
        "hgnc": "HGNC:15889",
        "name": "FERM domain containing kindlin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fermt1"
      }
    ]
  }
}