{
  "url": "https://dantelabs.com/traits/delayed-puberty",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "delayed-puberty",
    "id": "HP:0000823",
    "name": "Delayed puberty",
    "definition": "Passing the age when puberty normally occurs with no physical or hormonal signs of the onset of puberty.",
    "synonyms": [
      "Delayed pubertal development",
      "Delayed pubertal growth",
      "Pubertal delay"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      },
      {
        "slug": "growth-abnormality",
        "name": "Growth abnormality",
        "url": "https://dantelabs.com/traits/growth-abnormality"
      }
    ],
    "broader": [
      {
        "slug": "growth-delay",
        "name": "Growth delay",
        "url": "https://dantelabs.com/traits/growth-delay"
      },
      {
        "slug": "puberty-and-gonadal-disorders",
        "name": "Puberty and gonadal disorders",
        "url": "https://dantelabs.com/traits/puberty-and-gonadal-disorders"
      }
    ],
    "narrower": [
      {
        "slug": "delayed-menarche",
        "name": "Delayed start of first period",
        "genes": 25,
        "url": "https://dantelabs.com/traits/delayed-menarche"
      },
      {
        "slug": "delayed-thelarche",
        "name": "Delayed thelarche",
        "genes": 2,
        "url": "https://dantelabs.com/traits/delayed-thelarche"
      }
    ],
    "genes": [
      {
        "slug": "bmp15",
        "symbol": "BMP15",
        "hgnc": "HGNC:1068",
        "name": "bone morphogenetic protein 15",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bmp15"
      },
      {
        "slug": "btk",
        "symbol": "BTK",
        "hgnc": "HGNC:1133",
        "name": "Bruton tyrosine kinase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/btk"
      },
      {
        "slug": "dcaf17",
        "symbol": "DCAF17",
        "hgnc": "HGNC:25784",
        "name": "DDB1 and CUL4 associated factor 17",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dcaf17"
      },
      {
        "slug": "esr1",
        "symbol": "ESR1",
        "hgnc": "HGNC:3467",
        "name": "estrogen receptor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/esr1"
      },
      {
        "slug": "fam111b",
        "symbol": "FAM111B",
        "hgnc": "HGNC:24200",
        "name": "FAM111 trypsin like peptidase B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fam111b"
      },
      {
        "slug": "gtf3c3",
        "symbol": "GTF3C3",
        "hgnc": "HGNC:4666",
        "name": "general transcription factor IIIC subunit 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gtf3c3"
      },
      {
        "slug": "hrob",
        "symbol": "HROB",
        "hgnc": "HGNC:28460",
        "name": "homologous recombination factor with OB-fold",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hrob"
      },
      {
        "slug": "lepr",
        "symbol": "LEPR",
        "hgnc": "HGNC:6554",
        "name": "leptin receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lepr"
      },
      {
        "slug": "prdm13",
        "symbol": "PRDM13",
        "hgnc": "HGNC:13998",
        "name": "PR/SET domain 13",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdm13"
      },
      {
        "slug": "psmc3ip",
        "symbol": "PSMC3IP",
        "hgnc": "HGNC:17928",
        "name": "PSMC3 interacting protein",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/psmc3ip"
      },
      {
        "slug": "rbm28",
        "symbol": "RBM28",
        "hgnc": "HGNC:21863",
        "name": "RNA binding motif protein 28",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rbm28"
      },
      {
        "slug": "rnu2-2",
        "symbol": "RNU2-2",
        "hgnc": "HGNC:10152",
        "name": "RNA, U2 small nuclear 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu2-2"
      },
      {
        "slug": "rnu6atac",
        "symbol": "RNU6ATAC",
        "hgnc": "HGNC:34017",
        "name": "RNA, U6atac small nuclear",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6atac"
      },
      {
        "slug": "spidr",
        "symbol": "SPIDR",
        "hgnc": "HGNC:28971",
        "name": "scaffold protein involved in DNA repair",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/spidr"
      },
      {
        "slug": "taf13",
        "symbol": "TAF13",
        "hgnc": "HGNC:11546",
        "name": "TATA-box binding protein associated factor 13",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/taf13"
      },
      {
        "slug": "tra2b",
        "symbol": "TRA2B",
        "hgnc": "HGNC:10781",
        "name": "transformer 2 beta homolog",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tra2b"
      },
      {
        "slug": "zswim7",
        "symbol": "ZSWIM7",
        "hgnc": "HGNC:26993",
        "name": "zinc finger SWIM-type containing 7",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/zswim7"
      },
      {
        "slug": "anos1",
        "symbol": "ANOS1",
        "hgnc": "HGNC:6211",
        "name": "anosmin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/anos1"
      },
      {
        "slug": "atm",
        "symbol": "ATM",
        "hgnc": "HGNC:795",
        "name": "ATM serine/threonine kinase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/atm"
      },
      {
        "slug": "bnc1",
        "symbol": "BNC1",
        "hgnc": "HGNC:1081",
        "name": "basonuclin zinc finger protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bnc1"
      },
      {
        "slug": "ccdc141",
        "symbol": "CCDC141",
        "hgnc": "HGNC:26821",
        "name": "coiled-coil domain containing 141",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc141"
      },
      {
        "slug": "chd7",
        "symbol": "CHD7",
        "hgnc": "HGNC:20626",
        "name": "chromodomain helicase DNA binding protein 7",
        "frequency": "very-frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/chd7"
      },
      {
        "slug": "cyb5a",
        "symbol": "CYB5A",
        "hgnc": "HGNC:2570",
        "name": "cytochrome b5 type A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyb5a"
      },
      {
        "slug": "cyp11a1",
        "symbol": "CYP11A1",
        "hgnc": "HGNC:2590",
        "name": "cytochrome P450 family 11 subfamily A member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cyp11a1"
      },
      {
        "slug": "cyp17a1",
        "symbol": "CYP17A1",
        "hgnc": "HGNC:2593",
        "name": "cytochrome P450 family 17 subfamily A member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cyp17a1"
      },
      {
        "slug": "dcc",
        "symbol": "DCC",
        "hgnc": "HGNC:2701",
        "name": "DCC netrin 1 receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dcc"
      },
      {
        "slug": "dusp6",
        "symbol": "DUSP6",
        "hgnc": "HGNC:3072",
        "name": "dual specificity phosphatase 6",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dusp6"
      },
      {
        "slug": "emx2",
        "symbol": "EMX2",
        "hgnc": "HGNC:3341",
        "name": "empty spiracles homeobox 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/emx2"
      },
      {
        "slug": "fezf1",
        "symbol": "FEZF1",
        "hgnc": "HGNC:22788",
        "name": "FEZ family zinc finger 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fezf1"
      },
      {
        "slug": "fgf17",
        "symbol": "FGF17",
        "hgnc": "HGNC:3673",
        "name": "fibroblast growth factor 17",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/fgf17"
      },
      {
        "slug": "fgf8",
        "symbol": "FGF8",
        "hgnc": "HGNC:3686",
        "name": "fibroblast growth factor 8",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/fgf8"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "figla",
        "symbol": "FIGLA",
        "hgnc": "HGNC:24669",
        "name": "folliculogenesis specific bHLH transcription factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/figla"
      },
      {
        "slug": "flrt3",
        "symbol": "FLRT3",
        "hgnc": "HGNC:3762",
        "name": "fibronectin leucine rich transmembrane protein 3",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/flrt3"
      },
      {
        "slug": "fshb",
        "symbol": "FSHB",
        "hgnc": "HGNC:3964",
        "name": "follicle stimulating hormone subunit beta",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fshb"
      },
      {
        "slug": "fshr",
        "symbol": "FSHR",
        "hgnc": "HGNC:3969",
        "name": "follicle stimulating hormone receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fshr"
      },
      {
        "slug": "gba1",
        "symbol": "GBA1",
        "hgnc": "HGNC:4177",
        "name": "glucosylceramidase beta 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gba1"
      },
      {
        "slug": "hesx1",
        "symbol": "HESX1",
        "hgnc": "HGNC:4877",
        "name": "HESX homeobox 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/hesx1"
      },
      {
        "slug": "hs6st1",
        "symbol": "HS6ST1",
        "hgnc": "HGNC:5201",
        "name": "heparan sulfate 6-O-sulfotransferase 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hs6st1"
      },
      {
        "slug": "il17rd",
        "symbol": "IL17RD",
        "hgnc": "HGNC:17616",
        "name": "interleukin 17 receptor D",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il17rd"
      },
      {
        "slug": "insr",
        "symbol": "INSR",
        "hgnc": "HGNC:6091",
        "name": "insulin receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/insr"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "mrps22",
        "symbol": "MRPS22",
        "hgnc": "HGNC:14508",
        "name": "mitochondrial ribosomal protein S22",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mrps22"
      },
      {
        "slug": "msh4",
        "symbol": "MSH4",
        "hgnc": "HGNC:7327",
        "name": "mutS homolog 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msh4"
      },
      {
        "slug": "ndnf",
        "symbol": "NDNF",
        "hgnc": "HGNC:26256",
        "name": "neuron derived neurotrophic factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndnf"
      },
      {
        "slug": "nr5a1",
        "symbol": "NR5A1",
        "hgnc": "HGNC:7983",
        "name": "nuclear receptor subfamily 5 group A member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nr5a1"
      },
      {
        "slug": "nup107",
        "symbol": "NUP107",
        "hgnc": "HGNC:29914",
        "name": "nucleoporin 107",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nup107"
      },
      {
        "slug": "polr3a",
        "symbol": "POLR3A",
        "hgnc": "HGNC:30074",
        "name": "RNA polymerase III subunit A",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/polr3a"
      },
      {
        "slug": "polr3b",
        "symbol": "POLR3B",
        "hgnc": "HGNC:30348",
        "name": "RNA polymerase III subunit B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3b"
      },
      {
        "slug": "polr3h",
        "symbol": "POLR3H",
        "hgnc": "HGNC:30349",
        "name": "RNA polymerase III subunit H",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3h"
      },
      {
        "slug": "prok2",
        "symbol": "PROK2",
        "hgnc": "HGNC:18455",
        "name": "prokineticin 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prok2"
      },
      {
        "slug": "prokr2",
        "symbol": "PROKR2",
        "hgnc": "HGNC:15836",
        "name": "prokineticin receptor 2",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/prokr2"
      },
      {
        "slug": "rab18",
        "symbol": "RAB18",
        "hgnc": "HGNC:14244",
        "name": "RAB18, member RAS oncogene family",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab18"
      },
      {
        "slug": "rab3gap1",
        "symbol": "RAB3GAP1",
        "hgnc": "HGNC:17063",
        "name": "RAB3 GTPase activating protein catalytic subunit 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab3gap1"
      },
      {
        "slug": "rab3gap2",
        "symbol": "RAB3GAP2",
        "hgnc": "HGNC:17168",
        "name": "RAB3 GTPase activating non-catalytic protein subunit 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab3gap2"
      },
      {
        "slug": "scarb2",
        "symbol": "SCARB2",
        "hgnc": "HGNC:1665",
        "name": "scavenger receptor class B member 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scarb2"
      },
      {
        "slug": "sema3a",
        "symbol": "SEMA3A",
        "hgnc": "HGNC:10723",
        "name": "semaphorin 3A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema3a"
      },
      {
        "slug": "sema3e",
        "symbol": "SEMA3E",
        "hgnc": "HGNC:10727",
        "name": "semaphorin 3E",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema3e"
      },
      {
        "slug": "slc29a3",
        "symbol": "SLC29A3",
        "hgnc": "HGNC:23096",
        "name": "solute carrier family 29 member 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc29a3"
      },
      {
        "slug": "sox10",
        "symbol": "SOX10",
        "hgnc": "HGNC:11190",
        "name": "SRY-box transcription factor 10",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox10"
      },
      {
        "slug": "spry4",
        "symbol": "SPRY4",
        "hgnc": "HGNC:15533",
        "name": "sprouty RTK signaling antagonist 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/spry4"
      },
      {
        "slug": "tacr3",
        "symbol": "TACR3",
        "hgnc": "HGNC:11528",
        "name": "tachykinin receptor 3",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tacr3"
      },
      {
        "slug": "tbc1d20",
        "symbol": "TBC1D20",
        "hgnc": "HGNC:16133",
        "name": "TBC1 domain family member 20",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d20"
      },
      {
        "slug": "wdr11",
        "symbol": "WDR11",
        "hgnc": "HGNC:13831",
        "name": "WD repeat domain 11",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/wdr11"
      },
      {
        "slug": "ar",
        "symbol": "AR",
        "hgnc": "HGNC:644",
        "name": "androgen receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ar"
      },
      {
        "slug": "brcc3",
        "symbol": "BRCC3",
        "hgnc": "HGNC:24185",
        "name": "BRCA1/BRCA2-containing complex subunit 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brcc3"
      },
      {
        "slug": "cdon",
        "symbol": "CDON",
        "hgnc": "HGNC:17104",
        "name": "cell adhesion associated, oncogene regulated",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdon"
      },
      {
        "slug": "cpe",
        "symbol": "CPE",
        "hgnc": "HGNC:2303",
        "name": "carboxypeptidase E",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cpe"
      },
      {
        "slug": "dhx37",
        "symbol": "DHX37",
        "hgnc": "HGNC:17210",
        "name": "DEAH-box helicase 37",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhx37"
      },
      {
        "slug": "entpd1",
        "symbol": "ENTPD1",
        "hgnc": "HGNC:3363",
        "name": "ectonucleoside triphosphate diphosphohydrolase 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/entpd1"
      },
      {
        "slug": "galt",
        "symbol": "GALT",
        "hgnc": "HGNC:4135",
        "name": "galactose-1-phosphate uridylyltransferase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/galt"
      },
      {
        "slug": "gata4",
        "symbol": "GATA4",
        "hgnc": "HGNC:4173",
        "name": "GATA binding protein 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gata4"
      },
      {
        "slug": "ghr",
        "symbol": "GHR",
        "hgnc": "HGNC:4263",
        "name": "growth hormone receptor",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ghr"
      },
      {
        "slug": "gla",
        "symbol": "GLA",
        "hgnc": "HGNC:4296",
        "name": "galactosidase alpha",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gla"
      },
      {
        "slug": "gnrh1",
        "symbol": "GNRH1",
        "hgnc": "HGNC:4419",
        "name": "gonadotropin releasing hormone 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gnrh1"
      },
      {
        "slug": "gnrhr",
        "symbol": "GNRHR",
        "hgnc": "HGNC:4421",
        "name": "gonadotropin releasing hormone receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnrhr"
      },
      {
        "slug": "gpr161",
        "symbol": "GPR161",
        "hgnc": "HGNC:23694",
        "name": "G protein-coupled receptor 161",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpr161"
      },
      {
        "slug": "herc2",
        "symbol": "HERC2",
        "hgnc": "HGNC:4868",
        "name": "HECT and RLD domain containing E3 ubiquitin protein ligase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/herc2"
      },
      {
        "slug": "igfals",
        "symbol": "IGFALS",
        "hgnc": "HGNC:5468",
        "name": "insulin like growth factor binding protein acid labile subunit",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/igfals"
      },
      {
        "slug": "kiss1",
        "symbol": "KISS1",
        "hgnc": "HGNC:6341",
        "name": "KiSS-1 metastasis suppressor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiss1"
      },
      {
        "slug": "kiss1r",
        "symbol": "KISS1R",
        "hgnc": "HGNC:4510",
        "name": "KISS1 receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiss1r"
      },
      {
        "slug": "lhx4",
        "symbol": "LHX4",
        "hgnc": "HGNC:21734",
        "name": "LIM homeobox 4",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lhx4"
      },
      {
        "slug": "lpin2",
        "symbol": "LPIN2",
        "hgnc": "HGNC:14450",
        "name": "lipin 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lpin2"
      },
      {
        "slug": "magel2",
        "symbol": "MAGEL2",
        "hgnc": "HGNC:6814",
        "name": "MAGE family member L2",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/magel2"
      },
      {
        "slug": "map3k1",
        "symbol": "MAP3K1",
        "hgnc": "HGNC:6848",
        "name": "mitogen-activated protein kinase kinase kinase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k1"
      },
      {
        "slug": "mkrn3",
        "symbol": "MKRN3",
        "hgnc": "HGNC:7114",
        "name": "makorin ring finger protein 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mkrn3"
      },
      {
        "slug": "ndn",
        "symbol": "NDN",
        "hgnc": "HGNC:7675",
        "name": "necdin, MAGE family member",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/ndn"
      },
      {
        "slug": "nhlh2",
        "symbol": "NHLH2",
        "hgnc": "HGNC:7818",
        "name": "nescient helix-loop-helix 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nhlh2"
      },
      {
        "slug": "nono",
        "symbol": "NONO",
        "hgnc": "HGNC:7871",
        "name": "non-POU domain containing octamer binding",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nono"
      },
      {
        "slug": "npap1",
        "symbol": "NPAP1",
        "hgnc": "HGNC:1190",
        "name": "nuclear pore associated protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npap1"
      },
      {
        "slug": "nr0b1",
        "symbol": "NR0B1",
        "hgnc": "HGNC:7960",
        "name": "nuclear receptor subfamily 0 group B member 1",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/nr0b1"
      },
      {
        "slug": "nsmf",
        "symbol": "NSMF",
        "hgnc": "HGNC:29843",
        "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsmf"
      },
      {
        "slug": "oca2",
        "symbol": "OCA2",
        "hgnc": "HGNC:8101",
        "name": "OCA2 melanosomal transmembrane protein",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/oca2"
      },
      {
        "slug": "polr3gl",
        "symbol": "POLR3GL",
        "hgnc": "HGNC:28466",
        "name": "RNA polymerase III subunit GL",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3gl"
      },
      {
        "slug": "ppp1r15b",
        "symbol": "PPP1R15B",
        "hgnc": "HGNC:14951",
        "name": "protein phosphatase 1 regulatory subunit 15B",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ppp1r15b"
      },
      {
        "slug": "pus1",
        "symbol": "PUS1",
        "hgnc": "HGNC:15508",
        "name": "pseudouridine synthase 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pus1"
      },
      {
        "slug": "pwar1",
        "symbol": "PWAR1",
        "hgnc": "HGNC:30089",
        "name": "Prader Willi/Angelman region RNA 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pwar1"
      },
      {
        "slug": "pwrn1",
        "symbol": "PWRN1",
        "hgnc": "HGNC:33235",
        "name": "Prader-Willi region non-protein coding RNA 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pwrn1"
      },
      {
        "slug": "pygl",
        "symbol": "PYGL",
        "hgnc": "HGNC:9725",
        "name": "glycogen phosphorylase L",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pygl"
      },
      {
        "slug": "robo1",
        "symbol": "ROBO1",
        "hgnc": "HGNC:10249",
        "name": "roundabout guidance receptor 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/robo1"
      },
      {
        "slug": "smpd1",
        "symbol": "SMPD1",
        "hgnc": "HGNC:11120",
        "name": "sphingomyelin phosphodiesterase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smpd1"
      },
      {
        "slug": "snord115-1",
        "symbol": "SNORD115-1",
        "hgnc": "HGNC:33020",
        "name": "small nucleolar RNA, C/D box 115-1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snord115-1"
      },
      {
        "slug": "snord116-1",
        "symbol": "SNORD116-1",
        "hgnc": "HGNC:33067",
        "name": "small nucleolar RNA, C/D box 116-1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snord116-1"
      },
      {
        "slug": "snrpn",
        "symbol": "SNRPN",
        "hgnc": "HGNC:11164",
        "name": "small nuclear ribonucleoprotein polypeptide N",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/snrpn"
      },
      {
        "slug": "sox11",
        "symbol": "SOX11",
        "hgnc": "HGNC:11191",
        "name": "SRY-box transcription factor 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox11"
      },
      {
        "slug": "sox9",
        "symbol": "SOX9",
        "hgnc": "HGNC:11204",
        "name": "SRY-box transcription factor 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox9"
      },
      {
        "slug": "sry",
        "symbol": "SRY",
        "hgnc": "HGNC:11311",
        "name": "sex determining region Y",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sry"
      },
      {
        "slug": "stat1",
        "symbol": "STAT1",
        "hgnc": "HGNC:11362",
        "name": "signal transducer and activator of transcription 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/stat1"
      },
      {
        "slug": "stat5b",
        "symbol": "STAT5B",
        "hgnc": "HGNC:11367",
        "name": "signal transducer and activator of transcription 5B",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/stat5b"
      },
      {
        "slug": "tac3",
        "symbol": "TAC3",
        "hgnc": "HGNC:11521",
        "name": "tachykinin precursor 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tac3"
      },
      {
        "slug": "tbx3",
        "symbol": "TBX3",
        "hgnc": "HGNC:11602",
        "name": "T-box transcription factor 3",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tbx3"
      },
      {
        "slug": "trmt10a",
        "symbol": "TRMT10A",
        "hgnc": "HGNC:28403",
        "name": "tRNA methyltransferase 10A",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trmt10a"
      },
      {
        "slug": "vamp7",
        "symbol": "VAMP7",
        "hgnc": "HGNC:11486",
        "name": "vesicle associated membrane protein 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vamp7"
      },
      {
        "slug": "vps13b",
        "symbol": "VPS13B",
        "hgnc": "HGNC:2183",
        "name": "vacuolar protein sorting 13 homolog B",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/vps13b"
      },
      {
        "slug": "wfs1",
        "symbol": "WFS1",
        "hgnc": "HGNC:12762",
        "name": "wolframin ER transmembrane glycoprotein",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wfs1"
      },
      {
        "slug": "wt1",
        "symbol": "WT1",
        "hgnc": "HGNC:12796",
        "name": "WT1 transcription factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wt1"
      },
      {
        "slug": "wwox",
        "symbol": "WWOX",
        "hgnc": "HGNC:12799",
        "name": "WW domain containing oxidoreductase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wwox"
      },
      {
        "slug": "yars2",
        "symbol": "YARS2",
        "hgnc": "HGNC:24249",
        "name": "tyrosyl-tRNA synthetase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/yars2"
      },
      {
        "slug": "zbtb20",
        "symbol": "ZBTB20",
        "hgnc": "HGNC:13503",
        "name": "zinc finger and BTB domain containing 20",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zbtb20"
      },
      {
        "slug": "zfpm2",
        "symbol": "ZFPM2",
        "hgnc": "HGNC:16700",
        "name": "zinc finger protein, FOG family member 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfpm2"
      },
      {
        "slug": "aip",
        "symbol": "AIP",
        "hgnc": "HGNC:358",
        "name": "AHR interacting HSP90 co-chaperone",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aip"
      },
      {
        "slug": "alx4",
        "symbol": "ALX4",
        "hgnc": "HGNC:450",
        "name": "ALX homeobox 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alx4"
      },
      {
        "slug": "atad3a",
        "symbol": "ATAD3A",
        "hgnc": "HGNC:25567",
        "name": "ATPase family AAA domain containing 3A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atad3a"
      },
      {
        "slug": "braf",
        "symbol": "BRAF",
        "hgnc": "HGNC:1097",
        "name": "B-Raf proto-oncogene, serine/threonine kinase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/braf"
      },
      {
        "slug": "brd4",
        "symbol": "BRD4",
        "hgnc": "HGNC:13575",
        "name": "bromodomain containing 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brd4"
      },
      {
        "slug": "cars1",
        "symbol": "CARS1",
        "hgnc": "HGNC:1493",
        "name": "cysteinyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cars1"
      },
      {
        "slug": "cdh23",
        "symbol": "CDH23",
        "hgnc": "HGNC:13733",
        "name": "cadherin related 23",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdh23"
      },
      {
        "slug": "cisd2",
        "symbol": "CISD2",
        "hgnc": "HGNC:24212",
        "name": "CDGSH iron sulfur domain 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cisd2"
      },
      {
        "slug": "clcnkb",
        "symbol": "CLCNKB",
        "hgnc": "HGNC:2027",
        "name": "chloride voltage-gated channel Kb",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcnkb"
      },
      {
        "slug": "col7a1",
        "symbol": "COL7A1",
        "hgnc": "HGNC:2214",
        "name": "collagen type VII alpha 1 chain",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col7a1"
      },
      {
        "slug": "ctnnb1",
        "symbol": "CTNNB1",
        "hgnc": "HGNC:2514",
        "name": "catenin beta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctnnb1"
      },
      {
        "slug": "dact1",
        "symbol": "DACT1",
        "hgnc": "HGNC:17748",
        "name": "dishevelled binding antagonist of beta catenin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dact1"
      },
      {
        "slug": "diaph1",
        "symbol": "DIAPH1",
        "hgnc": "HGNC:2876",
        "name": "diaphanous related formin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/diaph1"
      },
      {
        "slug": "eif5a",
        "symbol": "EIF5A",
        "hgnc": "HGNC:3300",
        "name": "eukaryotic translation initiation factor 5A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eif5a"
      },
      {
        "slug": "ext2",
        "symbol": "EXT2",
        "hgnc": "HGNC:3513",
        "name": "exostosin glycosyltransferase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ext2"
      },
      {
        "slug": "foxa2",
        "symbol": "FOXA2",
        "hgnc": "HGNC:5022",
        "name": "forkhead box A2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxa2"
      },
      {
        "slug": "ghsr",
        "symbol": "GHSR",
        "hgnc": "HGNC:4267",
        "name": "growth hormone secretagogue receptor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ghsr"
      },
      {
        "slug": "gli2",
        "symbol": "GLI2",
        "hgnc": "HGNC:4318",
        "name": "GLI family zinc finger 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gli2"
      },
      {
        "slug": "hbb",
        "symbol": "HBB",
        "hgnc": "HGNC:4827",
        "name": "hemoglobin subunit beta",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hbb"
      },
      {
        "slug": "hdac8",
        "symbol": "HDAC8",
        "hgnc": "HGNC:13315",
        "name": "histone deacetylase 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hdac8"
      },
      {
        "slug": "map3k7",
        "symbol": "MAP3K7",
        "hgnc": "HGNC:6859",
        "name": "mitogen-activated protein kinase kinase kinase 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k7"
      },
      {
        "slug": "mau2",
        "symbol": "MAU2",
        "hgnc": "HGNC:29140",
        "name": "MAU2 sister chromatid cohesion factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mau2"
      },
      {
        "slug": "men1",
        "symbol": "MEN1",
        "hgnc": "HGNC:7010",
        "name": "menin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/men1"
      },
      {
        "slug": "mmp1",
        "symbol": "MMP1",
        "hgnc": "HGNC:7155",
        "name": "matrix metallopeptidase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmp1"
      },
      {
        "slug": "mt-atp8",
        "symbol": "MT-ATP8",
        "hgnc": "HGNC:7415",
        "name": "mitochondrially encoded ATP synthase membrane subunit 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-atp8"
      },
      {
        "slug": "mt-tl1",
        "symbol": "MT-TL1",
        "hgnc": "HGNC:7490",
        "name": "mitochondrially encoded tRNA-Leu (UUA/G) 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-tl1"
      },
      {
        "slug": "ndp",
        "symbol": "NDP",
        "hgnc": "HGNC:7678",
        "name": "norrin cystine knot growth factor NDP",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndp"
      },
      {
        "slug": "nf1",
        "symbol": "NF1",
        "hgnc": "HGNC:7765",
        "name": "neurofibromin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nf1"
      },
      {
        "slug": "nipbl",
        "symbol": "NIPBL",
        "hgnc": "HGNC:28862",
        "name": "NIPBL cohesin loading factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nipbl"
      },
      {
        "slug": "nlrp3",
        "symbol": "NLRP3",
        "hgnc": "HGNC:16400",
        "name": "NLR family pyrin domain containing 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nlrp3"
      },
      {
        "slug": "notch2",
        "symbol": "NOTCH2",
        "hgnc": "HGNC:7882",
        "name": "notch receptor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/notch2"
      },
      {
        "slug": "ocrl",
        "symbol": "OCRL",
        "hgnc": "HGNC:8108",
        "name": "OCRL inositol polyphosphate-5-phosphatase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ocrl"
      },
      {
        "slug": "otx2",
        "symbol": "OTX2",
        "hgnc": "HGNC:8522",
        "name": "orthodenticle homeobox 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otx2"
      },
      {
        "slug": "pcsk1",
        "symbol": "PCSK1",
        "hgnc": "HGNC:8743",
        "name": "proprotein convertase subtilisin/kexin type 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pcsk1"
      },
      {
        "slug": "pgm1",
        "symbol": "PGM1",
        "hgnc": "HGNC:8905",
        "name": "phosphoglucomutase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pgm1"
      },
      {
        "slug": "phf21a",
        "symbol": "PHF21A",
        "hgnc": "HGNC:24156",
        "name": "PHD finger protein 21A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phf21a"
      },
      {
        "slug": "phka2",
        "symbol": "PHKA2",
        "hgnc": "HGNC:8926",
        "name": "phosphorylase kinase regulatory subunit alpha 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phka2"
      },
      {
        "slug": "phkg2",
        "symbol": "PHKG2",
        "hgnc": "HGNC:8931",
        "name": "phosphorylase kinase catalytic subunit gamma 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phkg2"
      },
      {
        "slug": "pomc",
        "symbol": "POMC",
        "hgnc": "HGNC:9201",
        "name": "proopiomelanocortin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomc"
      },
      {
        "slug": "por",
        "symbol": "POR",
        "hgnc": "HGNC:9208",
        "name": "cytochrome p450 oxidoreductase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/por"
      },
      {
        "slug": "pou1f1",
        "symbol": "POU1F1",
        "hgnc": "HGNC:9210",
        "name": "POU class 1 homeobox 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pou1f1"
      },
      {
        "slug": "prop1",
        "symbol": "PROP1",
        "hgnc": "HGNC:9455",
        "name": "PROP paired-like homeobox 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prop1"
      },
      {
        "slug": "ptrh2",
        "symbol": "PTRH2",
        "hgnc": "HGNC:24265",
        "name": "peptidyl-tRNA hydrolase 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ptrh2"
      },
      {
        "slug": "rad21",
        "symbol": "RAD21",
        "hgnc": "HGNC:9811",
        "name": "RAD21 cohesin complex component",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad21"
      },
      {
        "slug": "rai1",
        "symbol": "RAI1",
        "hgnc": "HGNC:9834",
        "name": "retinoic acid induced 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rai1"
      },
      {
        "slug": "rpl10",
        "symbol": "RPL10",
        "hgnc": "HGNC:10298",
        "name": "ribosomal protein L10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpl10"
      },
      {
        "slug": "rrm2b",
        "symbol": "RRM2B",
        "hgnc": "HGNC:17296",
        "name": "ribonucleotide reductase regulatory TP53 inducible subunit M2B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rrm2b"
      },
      {
        "slug": "sall1",
        "symbol": "SALL1",
        "hgnc": "HGNC:10524",
        "name": "spalt like transcription factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sall1"
      },
      {
        "slug": "slc12a3",
        "symbol": "SLC12A3",
        "hgnc": "HGNC:10912",
        "name": "solute carrier family 12 member 3",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc12a3"
      },
      {
        "slug": "slc37a4",
        "symbol": "SLC37A4",
        "hgnc": "HGNC:4061",
        "name": "solute carrier family 37 member 4",
        "frequency": "occasional",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/slc37a4"
      },
      {
        "slug": "smc1a",
        "symbol": "SMC1A",
        "hgnc": "HGNC:11111",
        "name": "structural maintenance of chromosomes 1A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smc1a"
      },
      {
        "slug": "smc3",
        "symbol": "SMC3",
        "hgnc": "HGNC:2468",
        "name": "structural maintenance of chromosomes 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smc3"
      },
      {
        "slug": "sox3",
        "symbol": "SOX3",
        "hgnc": "HGNC:11199",
        "name": "SRY-box transcription factor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox3"
      },
      {
        "slug": "stat3",
        "symbol": "STAT3",
        "hgnc": "HGNC:11364",
        "name": "signal transducer and activator of transcription 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stat3"
      },
      {
        "slug": "tgfb1",
        "symbol": "TGFB1",
        "hgnc": "HGNC:11766",
        "name": "transforming growth factor beta 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tgfb1"
      },
      {
        "slug": "trip4",
        "symbol": "TRIP4",
        "hgnc": "HGNC:12310",
        "name": "thyroid hormone receptor interactor 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trip4"
      },
      {
        "slug": "usp9x",
        "symbol": "USP9X",
        "hgnc": "HGNC:12632",
        "name": "ubiquitin specific peptidase 9 X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp9x"
      },
      {
        "slug": "zfx",
        "symbol": "ZFX",
        "hgnc": "HGNC:12869",
        "name": "zinc finger protein X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfx"
      },
      {
        "slug": "zmpste24",
        "symbol": "ZMPSTE24",
        "hgnc": "HGNC:12877",
        "name": "zinc metallopeptidase STE24",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmpste24"
      },
      {
        "slug": "sptbn1",
        "symbol": "SPTBN1",
        "hgnc": "HGNC:11275",
        "name": "spectrin beta, non-erythrocytic 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sptbn1"
      },
      {
        "slug": "aldoa",
        "symbol": "ALDOA",
        "hgnc": "HGNC:414",
        "name": "aldolase, fructose-bisphosphate A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldoa"
      },
      {
        "slug": "cenpt",
        "symbol": "CENPT",
        "hgnc": "HGNC:25787",
        "name": "centromere protein T",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cenpt"
      },
      {
        "slug": "ctns",
        "symbol": "CTNS",
        "hgnc": "HGNC:2518",
        "name": "cystinosin, lysosomal cystine transporter",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctns"
      },
      {
        "slug": "cul4b",
        "symbol": "CUL4B",
        "hgnc": "HGNC:2555",
        "name": "cullin 4B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cul4b"
      },
      {
        "slug": "eif2s3",
        "symbol": "EIF2S3",
        "hgnc": "HGNC:3267",
        "name": "eukaryotic translation initiation factor 2 subunit gamma",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eif2s3"
      },
      {
        "slug": "fgd1",
        "symbol": "FGD1",
        "hgnc": "HGNC:3663",
        "name": "FYVE, RhoGEF and PH domain containing 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgd1"
      },
      {
        "slug": "g6pc1",
        "symbol": "G6PC1",
        "hgnc": "HGNC:4056",
        "name": "glucose-6-phosphatase catalytic subunit 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/g6pc1"
      },
      {
        "slug": "gmnn",
        "symbol": "GMNN",
        "hgnc": "HGNC:17493",
        "name": "geminin DNA replication inhibitor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gmnn"
      },
      {
        "slug": "hla-dqa1",
        "symbol": "HLA-DQA1",
        "hgnc": "HGNC:4942",
        "name": "major histocompatibility complex, class II, DQ alpha 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dqa1"
      },
      {
        "slug": "hla-dqb1",
        "symbol": "HLA-DQB1",
        "hgnc": "HGNC:4944",
        "name": "major histocompatibility complex, class II, DQ beta 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dqb1"
      },
      {
        "slug": "lgr4",
        "symbol": "LGR4",
        "hgnc": "HGNC:13299",
        "name": "leucine rich repeat containing G protein-coupled receptor 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lgr4"
      },
      {
        "slug": "lhb",
        "symbol": "LHB",
        "hgnc": "HGNC:6584",
        "name": "luteinizing hormone subunit beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lhb"
      },
      {
        "slug": "msmo1",
        "symbol": "MSMO1",
        "hgnc": "HGNC:10545",
        "name": "methylsterol monooxygenase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msmo1"
      },
      {
        "slug": "phf6",
        "symbol": "PHF6",
        "hgnc": "HGNC:18145",
        "name": "PHD finger protein 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phf6"
      },
      {
        "slug": "pnpla6",
        "symbol": "PNPLA6",
        "hgnc": "HGNC:16268",
        "name": "patatin like domain 6, lysophospholipase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnpla6"
      },
      {
        "slug": "pof1b",
        "symbol": "POF1B",
        "hgnc": "HGNC:13711",
        "name": "POF1B actin binding protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pof1b"
      },
      {
        "slug": "ptpn11",
        "symbol": "PTPN11",
        "hgnc": "HGNC:9644",
        "name": "protein tyrosine phosphatase non-receptor type 11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptpn11"
      },
      {
        "slug": "tcf12",
        "symbol": "TCF12",
        "hgnc": "HGNC:11623",
        "name": "transcription factor 12",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tcf12"
      },
      {
        "slug": "tgfb2",
        "symbol": "TGFB2",
        "hgnc": "HGNC:11768",
        "name": "transforming growth factor beta 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfb2"
      }
    ]
  }
}