{
  "url": "https://dantelabs.com/traits/central-hypoventilation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "central-hypoventilation",
    "id": "HP:0007110",
    "name": "Central hypoventilation",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-respiratory-system",
        "name": "Abnormality of the respiratory system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system"
      }
    ],
    "broader": [
      {
        "slug": "hypoventilation",
        "name": "Slow breathing",
        "url": "https://dantelabs.com/traits/hypoventilation"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "lbx1",
        "symbol": "LBX1",
        "hgnc": "HGNC:16960",
        "name": "ladybird homeobox 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lbx1"
      },
      {
        "slug": "phox2b",
        "symbol": "PHOX2B",
        "hgnc": "HGNC:9143",
        "name": "paired like homeobox 2B",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/phox2b"
      },
      {
        "slug": "ascl1",
        "symbol": "ASCL1",
        "hgnc": "HGNC:738",
        "name": "achaete-scute family bHLH transcription factor 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ascl1"
      },
      {
        "slug": "dctn1",
        "symbol": "DCTN1",
        "hgnc": "HGNC:2711",
        "name": "dynactin subunit 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dctn1"
      },
      {
        "slug": "ret",
        "symbol": "RET",
        "hgnc": "HGNC:9967",
        "name": "ret proto-oncogene",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ret"
      },
      {
        "slug": "hoxa1",
        "symbol": "HOXA1",
        "hgnc": "HGNC:5099",
        "name": "homeobox A1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hoxa1"
      },
      {
        "slug": "crls1",
        "symbol": "CRLS1",
        "hgnc": "HGNC:16148",
        "name": "cardiolipin synthase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crls1"
      },
      {
        "slug": "fbxo22",
        "symbol": "FBXO22",
        "hgnc": "HGNC:13593",
        "name": "F-box protein 22",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxo22"
      },
      {
        "slug": "mypn",
        "symbol": "MYPN",
        "hgnc": "HGNC:23246",
        "name": "myopalladin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mypn"
      },
      {
        "slug": "tpm2",
        "symbol": "TPM2",
        "hgnc": "HGNC:12011",
        "name": "tropomyosin 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpm2"
      },
      {
        "slug": "tpm3",
        "symbol": "TPM3",
        "hgnc": "HGNC:12012",
        "name": "tropomyosin 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpm3"
      },
      {
        "slug": "alk",
        "symbol": "ALK",
        "hgnc": "HGNC:427",
        "name": "ALK receptor tyrosine kinase",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alk"
      },
      {
        "slug": "mecp2",
        "symbol": "MECP2",
        "hgnc": "HGNC:6990",
        "name": "methyl-CpG binding protein 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mecp2"
      },
      {
        "slug": "ndufaf2",
        "symbol": "NDUFAF2",
        "hgnc": "HGNC:28086",
        "name": "NADH:ubiquinone oxidoreductase complex assembly factor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndufaf2"
      }
    ]
  }
}