{
  "url": "https://dantelabs.com/traits/astigmatism",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "astigmatism",
    "id": "HP:0000483",
    "name": "Astigmatism",
    "definition": "A type of refraction error associated with abnormal curvatures on the anterior and/or posterior surface of the cornea.",
    "synonyms": [
      "Abnormal curving of the cornea or lens of the eye"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-refraction",
        "name": "Abnormality of refraction",
        "url": "https://dantelabs.com/traits/abnormality-of-refraction"
      },
      {
        "slug": "abnormality-of-the-curvature-of-the-cornea",
        "name": "Abnormality of the curvature of the cornea",
        "url": "https://dantelabs.com/traits/abnormality-of-the-curvature-of-the-cornea"
      }
    ],
    "narrower": [
      {
        "slug": "hyperopic-astigmatism",
        "name": "Hyperopic astigmatism",
        "genes": 7,
        "url": "https://dantelabs.com/traits/hyperopic-astigmatism"
      },
      {
        "slug": "myopic-astigmatism",
        "name": "Myopic astigmatism",
        "genes": 7,
        "url": "https://dantelabs.com/traits/myopic-astigmatism"
      },
      {
        "slug": "corneal-astigmatism",
        "name": "Corneal astigmatism",
        "genes": 2,
        "url": "https://dantelabs.com/traits/corneal-astigmatism"
      },
      {
        "slug": "irregular-astigmatism",
        "name": "Irregular astigmatism",
        "genes": 2,
        "url": "https://dantelabs.com/traits/irregular-astigmatism"
      },
      {
        "slug": "mixed-astigmatism",
        "name": "Mixed astigmatism",
        "genes": 1,
        "url": "https://dantelabs.com/traits/mixed-astigmatism"
      }
    ],
    "genes": [
      {
        "slug": "ahdc1",
        "symbol": "AHDC1",
        "hgnc": "HGNC:25230",
        "name": "AT-hook DNA binding motif containing 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahdc1"
      },
      {
        "slug": "arhgef2",
        "symbol": "ARHGEF2",
        "hgnc": "HGNC:682",
        "name": "Rho/Rac guanine nucleotide exchange factor 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arhgef2"
      },
      {
        "slug": "arl6",
        "symbol": "ARL6",
        "hgnc": "HGNC:13210",
        "name": "ARF like GTPase 6",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/arl6"
      },
      {
        "slug": "bbs1",
        "symbol": "BBS1",
        "hgnc": "HGNC:966",
        "name": "Bardet-Biedl syndrome 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs1"
      },
      {
        "slug": "cacna1f",
        "symbol": "CACNA1F",
        "hgnc": "HGNC:1393",
        "name": "calcium voltage-gated channel subunit alpha1 F",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/cacna1f"
      },
      {
        "slug": "ccdc28b",
        "symbol": "CCDC28B",
        "hgnc": "HGNC:28163",
        "name": "coiled-coil domain containing 28B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc28b"
      },
      {
        "slug": "cldn11",
        "symbol": "CLDN11",
        "hgnc": "HGNC:8514",
        "name": "claudin 11",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cldn11"
      },
      {
        "slug": "col9a1",
        "symbol": "COL9A1",
        "hgnc": "HGNC:2217",
        "name": "collagen type IX alpha 1 chain",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col9a1"
      },
      {
        "slug": "col9a3",
        "symbol": "COL9A3",
        "hgnc": "HGNC:2219",
        "name": "collagen type IX alpha 3 chain",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col9a3"
      },
      {
        "slug": "crnkl1",
        "symbol": "CRNKL1",
        "hgnc": "HGNC:15762",
        "name": "crooked neck pre-mRNA splicing factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crnkl1"
      },
      {
        "slug": "efemp1",
        "symbol": "EFEMP1",
        "hgnc": "HGNC:3218",
        "name": "EGF-like fibulin extracellular matrix protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/efemp1"
      },
      {
        "slug": "eri1",
        "symbol": "ERI1",
        "hgnc": "HGNC:23994",
        "name": "exoribonuclease 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eri1"
      },
      {
        "slug": "exosc5",
        "symbol": "EXOSC5",
        "hgnc": "HGNC:24662",
        "name": "exosome component 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/exosc5"
      },
      {
        "slug": "fanci",
        "symbol": "FANCI",
        "hgnc": "HGNC:25568",
        "name": "FA complementation group I",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fanci"
      },
      {
        "slug": "fbn1",
        "symbol": "FBN1",
        "hgnc": "HGNC:3603",
        "name": "fibrillin 1",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/fbn1"
      },
      {
        "slug": "ift172",
        "symbol": "IFT172",
        "hgnc": "HGNC:30391",
        "name": "intraflagellar transport 172",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ift172"
      },
      {
        "slug": "ints11",
        "symbol": "INTS11",
        "hgnc": "HGNC:26052",
        "name": "integrator complex subunit 11",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ints11"
      },
      {
        "slug": "jkamp",
        "symbol": "JKAMP",
        "hgnc": "HGNC:20184",
        "name": "JNK1/MAPK8 associated membrane protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jkamp"
      },
      {
        "slug": "kdm2b",
        "symbol": "KDM2B",
        "hgnc": "HGNC:13610",
        "name": "lysine demethylase 2B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm2b"
      },
      {
        "slug": "kdm6b",
        "symbol": "KDM6B",
        "hgnc": "HGNC:29012",
        "name": "lysine demethylase 6B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6b"
      },
      {
        "slug": "lig4",
        "symbol": "LIG4",
        "hgnc": "HGNC:6601",
        "name": "DNA ligase 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lig4"
      },
      {
        "slug": "mag",
        "symbol": "MAG",
        "hgnc": "HGNC:6783",
        "name": "myelin associated glycoprotein",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mag"
      },
      {
        "slug": "mir184",
        "symbol": "MIR184",
        "hgnc": "HGNC:31555",
        "name": "microRNA 184",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mir184"
      },
      {
        "slug": "nr6a1",
        "symbol": "NR6A1",
        "hgnc": "HGNC:7985",
        "name": "nuclear receptor subfamily 6 group A member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr6a1"
      },
      {
        "slug": "pigq",
        "symbol": "PIGQ",
        "hgnc": "HGNC:14135",
        "name": "phosphatidylinositol glycan anchor biosynthesis class Q",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigq"
      },
      {
        "slug": "rere",
        "symbol": "RERE",
        "hgnc": "HGNC:9965",
        "name": "arginine-glutamic acid dipeptide repeats",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rere"
      },
      {
        "slug": "slc38a8",
        "symbol": "SLC38A8",
        "hgnc": "HGNC:32434",
        "name": "solute carrier family 38 member 8",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc38a8"
      },
      {
        "slug": "tub",
        "symbol": "TUB",
        "hgnc": "HGNC:12406",
        "name": "TUB bipartite transcription factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tub"
      },
      {
        "slug": "ubap2l",
        "symbol": "UBAP2L",
        "hgnc": "HGNC:29877",
        "name": "ubiquitin associated protein 2 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubap2l"
      },
      {
        "slug": "ap3d1",
        "symbol": "AP3D1",
        "hgnc": "HGNC:568",
        "name": "adaptor related protein complex 3 subunit delta 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ap3d1"
      },
      {
        "slug": "dpyd",
        "symbol": "DPYD",
        "hgnc": "HGNC:3012",
        "name": "dihydropyrimidine dehydrogenase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dpyd"
      },
      {
        "slug": "gpr143",
        "symbol": "GPR143",
        "hgnc": "HGNC:20145",
        "name": "G protein-coupled receptor 143",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gpr143"
      },
      {
        "slug": "tceal1",
        "symbol": "TCEAL1",
        "hgnc": "HGNC:11616",
        "name": "transcription elongation factor A like 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tceal1"
      },
      {
        "slug": "tcf4",
        "symbol": "TCF4",
        "hgnc": "HGNC:11634",
        "name": "transcription factor 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tcf4"
      },
      {
        "slug": "adamts2",
        "symbol": "ADAMTS2",
        "hgnc": "HGNC:218",
        "name": "ADAM metallopeptidase with thrombospondin type 1 motif 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adamts2"
      },
      {
        "slug": "adamtsl2",
        "symbol": "ADAMTSL2",
        "hgnc": "HGNC:14631",
        "name": "ADAMTS like 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/adamtsl2"
      },
      {
        "slug": "aldh3a2",
        "symbol": "ALDH3A2",
        "hgnc": "HGNC:403",
        "name": "aldehyde dehydrogenase 3 family member A2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh3a2"
      },
      {
        "slug": "apc2",
        "symbol": "APC2",
        "hgnc": "HGNC:24036",
        "name": "APC regulator of Wnt signaling pathway 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apc2"
      },
      {
        "slug": "bbs9",
        "symbol": "BBS9",
        "hgnc": "HGNC:30000",
        "name": "Bardet-Biedl syndrome 9",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs9"
      },
      {
        "slug": "bloc1s3",
        "symbol": "BLOC1S3",
        "hgnc": "HGNC:20914",
        "name": "biogenesis of lysosomal organelles complex 1 subunit 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bloc1s3"
      },
      {
        "slug": "camta1",
        "symbol": "CAMTA1",
        "hgnc": "HGNC:18806",
        "name": "calmodulin binding transcription activator 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/camta1"
      },
      {
        "slug": "ccdc47",
        "symbol": "CCDC47",
        "hgnc": "HGNC:24856",
        "name": "coiled-coil domain containing 47",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc47"
      },
      {
        "slug": "chmp1a",
        "symbol": "CHMP1A",
        "hgnc": "HGNC:8740",
        "name": "charged multivesicular body protein 1A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chmp1a"
      },
      {
        "slug": "chst14",
        "symbol": "CHST14",
        "hgnc": "HGNC:24464",
        "name": "carbohydrate sulfotransferase 14",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/chst14"
      },
      {
        "slug": "dse",
        "symbol": "DSE",
        "hgnc": "HGNC:21144",
        "name": "dermatan sulfate epimerase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dse"
      },
      {
        "slug": "ebf3",
        "symbol": "EBF3",
        "hgnc": "HGNC:19087",
        "name": "EBF transcription factor 3",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ebf3"
      },
      {
        "slug": "hdac4",
        "symbol": "HDAC4",
        "hgnc": "HGNC:14063",
        "name": "histone deacetylase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hdac4"
      },
      {
        "slug": "hras",
        "symbol": "HRAS",
        "hgnc": "HGNC:5173",
        "name": "HRas proto-oncogene, GTPase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hras"
      },
      {
        "slug": "ints1",
        "symbol": "INTS1",
        "hgnc": "HGNC:24555",
        "name": "integrator complex subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ints1"
      },
      {
        "slug": "kat6a",
        "symbol": "KAT6A",
        "hgnc": "HGNC:13013",
        "name": "lysine acetyltransferase 6A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kat6a"
      },
      {
        "slug": "kdm5b",
        "symbol": "KDM5B",
        "hgnc": "HGNC:18039",
        "name": "lysine demethylase 5B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm5b"
      },
      {
        "slug": "kidins220",
        "symbol": "KIDINS220",
        "hgnc": "HGNC:29508",
        "name": "kinase D interacting substrate 220",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kidins220"
      },
      {
        "slug": "kmt2b",
        "symbol": "KMT2B",
        "hgnc": "HGNC:15840",
        "name": "lysine methyltransferase 2B",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kmt2b"
      },
      {
        "slug": "lmx1b",
        "symbol": "LMX1B",
        "hgnc": "HGNC:6654",
        "name": "LIM homeobox transcription factor 1 beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmx1b"
      },
      {
        "slug": "lrrc8c",
        "symbol": "LRRC8C",
        "hgnc": "HGNC:25075",
        "name": "leucine rich repeat containing 8 VRAC subunit C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrrc8c"
      },
      {
        "slug": "mbd5",
        "symbol": "MBD5",
        "hgnc": "HGNC:20444",
        "name": "methyl-CpG binding domain protein 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mbd5"
      },
      {
        "slug": "med16",
        "symbol": "MED16",
        "hgnc": "HGNC:17556",
        "name": "mediator complex subunit 16",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/med16"
      },
      {
        "slug": "myo1h",
        "symbol": "MYO1H",
        "hgnc": "HGNC:13879",
        "name": "myosin IH",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myo1h"
      },
      {
        "slug": "neurod2",
        "symbol": "NEUROD2",
        "hgnc": "HGNC:7763",
        "name": "neuronal differentiation 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/neurod2"
      },
      {
        "slug": "nfix",
        "symbol": "NFIX",
        "hgnc": "HGNC:7788",
        "name": "nuclear factor I X",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfix"
      },
      {
        "slug": "nsd1",
        "symbol": "NSD1",
        "hgnc": "HGNC:14234",
        "name": "nuclear receptor binding SET domain protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsd1"
      },
      {
        "slug": "pik3r1",
        "symbol": "PIK3R1",
        "hgnc": "HGNC:8979",
        "name": "phosphoinositide-3-kinase regulatory subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3r1"
      },
      {
        "slug": "pogz",
        "symbol": "POGZ",
        "hgnc": "HGNC:18801",
        "name": "pogo transposable element derived with ZNF domain",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pogz"
      },
      {
        "slug": "polr3gl",
        "symbol": "POLR3GL",
        "hgnc": "HGNC:28466",
        "name": "RNA polymerase III subunit GL",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3gl"
      },
      {
        "slug": "prdm5",
        "symbol": "PRDM5",
        "hgnc": "HGNC:9349",
        "name": "PR/SET domain 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdm5"
      },
      {
        "slug": "prmt7",
        "symbol": "PRMT7",
        "hgnc": "HGNC:25557",
        "name": "protein arginine methyltransferase 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prmt7"
      },
      {
        "slug": "rnf2",
        "symbol": "RNF2",
        "hgnc": "HGNC:10061",
        "name": "ring finger protein 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf2"
      },
      {
        "slug": "rnu4-2",
        "symbol": "RNU4-2",
        "hgnc": "HGNC:10193",
        "name": "RNA, U4 small nuclear 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4-2"
      },
      {
        "slug": "rnu5b-1",
        "symbol": "RNU5B-1",
        "hgnc": "HGNC:10212",
        "name": "RNA, U5B small nuclear 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu5b-1"
      },
      {
        "slug": "setd5",
        "symbol": "SETD5",
        "hgnc": "HGNC:25566",
        "name": "SET domain containing 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/setd5"
      },
      {
        "slug": "slc25a24",
        "symbol": "SLC25A24",
        "hgnc": "HGNC:20662",
        "name": "solute carrier family 25 member 24",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc25a24"
      },
      {
        "slug": "slc2a10",
        "symbol": "SLC2A10",
        "hgnc": "HGNC:13444",
        "name": "solute carrier family 2 member 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc2a10"
      },
      {
        "slug": "stxbp1",
        "symbol": "STXBP1",
        "hgnc": "HGNC:11444",
        "name": "syntaxin binding protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stxbp1"
      },
      {
        "slug": "tgfbi",
        "symbol": "TGFBI",
        "hgnc": "HGNC:11771",
        "name": "transforming growth factor beta induced",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tgfbi"
      },
      {
        "slug": "wac",
        "symbol": "WAC",
        "hgnc": "HGNC:17327",
        "name": "WW domain containing adaptor with coiled-coil",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wac"
      },
      {
        "slug": "znf469",
        "symbol": "ZNF469",
        "hgnc": "HGNC:23216",
        "name": "zinc finger protein 469",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf469"
      },
      {
        "slug": "aars1",
        "symbol": "AARS1",
        "hgnc": "HGNC:20",
        "name": "alanyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aars1"
      },
      {
        "slug": "adnp",
        "symbol": "ADNP",
        "hgnc": "HGNC:15766",
        "name": "activity dependent neuroprotector homeobox",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/adnp"
      },
      {
        "slug": "aebp1",
        "symbol": "AEBP1",
        "hgnc": "HGNC:303",
        "name": "AE binding protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aebp1"
      },
      {
        "slug": "ankrd11",
        "symbol": "ANKRD11",
        "hgnc": "HGNC:21316",
        "name": "ankyrin repeat domain 11",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ankrd11"
      },
      {
        "slug": "arcn1",
        "symbol": "ARCN1",
        "hgnc": "HGNC:649",
        "name": "archain 1 coat protein complex I subunit delta",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arcn1"
      },
      {
        "slug": "ash1l",
        "symbol": "ASH1L",
        "hgnc": "HGNC:19088",
        "name": "ASH1 like histone lysine methyltransferase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ash1l"
      },
      {
        "slug": "bap1",
        "symbol": "BAP1",
        "hgnc": "HGNC:950",
        "name": "BRCA1 associated deubiquitinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bap1"
      },
      {
        "slug": "bbip1",
        "symbol": "BBIP1",
        "hgnc": "HGNC:28093",
        "name": "BBSome interacting protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbip1"
      },
      {
        "slug": "bbs10",
        "symbol": "BBS10",
        "hgnc": "HGNC:26291",
        "name": "Bardet-Biedl syndrome 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs10"
      },
      {
        "slug": "bbs12",
        "symbol": "BBS12",
        "hgnc": "HGNC:26648",
        "name": "Bardet-Biedl syndrome 12",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs12"
      },
      {
        "slug": "bbs2",
        "symbol": "BBS2",
        "hgnc": "HGNC:967",
        "name": "Bardet-Biedl syndrome 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs2"
      },
      {
        "slug": "bbs4",
        "symbol": "BBS4",
        "hgnc": "HGNC:969",
        "name": "Bardet-Biedl syndrome 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs4"
      },
      {
        "slug": "bbs5",
        "symbol": "BBS5",
        "hgnc": "HGNC:970",
        "name": "Bardet-Biedl syndrome 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs5"
      },
      {
        "slug": "bbs7",
        "symbol": "BBS7",
        "hgnc": "HGNC:18758",
        "name": "Bardet-Biedl syndrome 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs7"
      },
      {
        "slug": "brca1",
        "symbol": "BRCA1",
        "hgnc": "HGNC:1100",
        "name": "BRCA1 DNA repair associated",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca1"
      },
      {
        "slug": "brca2",
        "symbol": "BRCA2",
        "hgnc": "HGNC:1101",
        "name": "BRCA2 DNA repair associated",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca2"
      },
      {
        "slug": "brip1",
        "symbol": "BRIP1",
        "hgnc": "HGNC:20473",
        "name": "BRCA1 interacting DNA helicase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brip1"
      },
      {
        "slug": "c1qbp",
        "symbol": "C1QBP",
        "hgnc": "HGNC:1243",
        "name": "complement C1q binding protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c1qbp"
      },
      {
        "slug": "camk2b",
        "symbol": "CAMK2B",
        "hgnc": "HGNC:1461",
        "name": "calcium/calmodulin dependent protein kinase II beta",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/camk2b"
      },
      {
        "slug": "camsap1",
        "symbol": "CAMSAP1",
        "hgnc": "HGNC:19946",
        "name": "calmodulin regulated spectrin associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/camsap1"
      },
      {
        "slug": "caprin1",
        "symbol": "CAPRIN1",
        "hgnc": "HGNC:6743",
        "name": "cell cycle associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/caprin1"
      },
      {
        "slug": "cars1",
        "symbol": "CARS1",
        "hgnc": "HGNC:1493",
        "name": "cysteinyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cars1"
      },
      {
        "slug": "cep19",
        "symbol": "CEP19",
        "hgnc": "HGNC:28209",
        "name": "centrosomal protein 19",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep19"
      },
      {
        "slug": "cep290",
        "symbol": "CEP290",
        "hgnc": "HGNC:29021",
        "name": "centrosomal protein 290",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep290"
      },
      {
        "slug": "cfap418",
        "symbol": "CFAP418",
        "hgnc": "HGNC:27232",
        "name": "cilia and flagella associated protein 418",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap418"
      },
      {
        "slug": "chd3",
        "symbol": "CHD3",
        "hgnc": "HGNC:1918",
        "name": "chromodomain helicase DNA binding protein 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd3"
      },
      {
        "slug": "cldn16",
        "symbol": "CLDN16",
        "hgnc": "HGNC:2037",
        "name": "claudin 16",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cldn16"
      },
      {
        "slug": "col4a5",
        "symbol": "COL4A5",
        "hgnc": "HGNC:2207",
        "name": "collagen type IV alpha 5 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a5"
      },
      {
        "slug": "col8a2",
        "symbol": "COL8A2",
        "hgnc": "HGNC:2216",
        "name": "collagen type VIII alpha 2 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col8a2"
      },
      {
        "slug": "creld1",
        "symbol": "CRELD1",
        "hgnc": "HGNC:14630",
        "name": "CRELD disulfide isomerase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/creld1"
      },
      {
        "slug": "dbr1",
        "symbol": "DBR1",
        "hgnc": "HGNC:15594",
        "name": "debranching RNA lariats 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dbr1"
      },
      {
        "slug": "dpagt1",
        "symbol": "DPAGT1",
        "hgnc": "HGNC:2995",
        "name": "dolichyl-phosphate N-acetylglucosaminephosphotransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dpagt1"
      },
      {
        "slug": "dyrk1a",
        "symbol": "DYRK1A",
        "hgnc": "HGNC:3091",
        "name": "dual specificity tyrosine phosphorylation regulated kinase 1A",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dyrk1a"
      },
      {
        "slug": "edem3",
        "symbol": "EDEM3",
        "hgnc": "HGNC:16787",
        "name": "ER degradation enhancing alpha-mannosidase like protein 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/edem3"
      },
      {
        "slug": "emc1",
        "symbol": "EMC1",
        "hgnc": "HGNC:28957",
        "name": "ER membrane protein complex subunit 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/emc1"
      },
      {
        "slug": "ercc2",
        "symbol": "ERCC2",
        "hgnc": "HGNC:3434",
        "name": "ERCC excision repair 2, TFIIH core complex helicase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc2"
      },
      {
        "slug": "ercc3",
        "symbol": "ERCC3",
        "hgnc": "HGNC:3435",
        "name": "ERCC excision repair 3, TFIIH core complex helicase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc3"
      },
      {
        "slug": "ercc4",
        "symbol": "ERCC4",
        "hgnc": "HGNC:3436",
        "name": "ERCC excision repair 4, endonuclease catalytic subunit",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ercc4"
      },
      {
        "slug": "faap100",
        "symbol": "FAAP100",
        "hgnc": "HGNC:26171",
        "name": "FA core complex associated protein 100",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/faap100"
      },
      {
        "slug": "fanca",
        "symbol": "FANCA",
        "hgnc": "HGNC:3582",
        "name": "FA complementation group A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fanca"
      },
      {
        "slug": "fancb",
        "symbol": "FANCB",
        "hgnc": "HGNC:3583",
        "name": "FA complementation group B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancb"
      },
      {
        "slug": "fancc",
        "symbol": "FANCC",
        "hgnc": "HGNC:3584",
        "name": "FA complementation group C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancc"
      },
      {
        "slug": "fancd2",
        "symbol": "FANCD2",
        "hgnc": "HGNC:3585",
        "name": "FA complementation group D2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancd2"
      },
      {
        "slug": "fance",
        "symbol": "FANCE",
        "hgnc": "HGNC:3586",
        "name": "FA complementation group E",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fance"
      },
      {
        "slug": "fancf",
        "symbol": "FANCF",
        "hgnc": "HGNC:3587",
        "name": "FA complementation group F",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancf"
      },
      {
        "slug": "fancg",
        "symbol": "FANCG",
        "hgnc": "HGNC:3588",
        "name": "FA complementation group G",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancg"
      },
      {
        "slug": "fancl",
        "symbol": "FANCL",
        "hgnc": "HGNC:20748",
        "name": "FA complementation group L",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancl"
      },
      {
        "slug": "fancm",
        "symbol": "FANCM",
        "hgnc": "HGNC:23168",
        "name": "FA complementation group M",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancm"
      },
      {
        "slug": "fem1b",
        "symbol": "FEM1B",
        "hgnc": "HGNC:3649",
        "name": "fem-1 homolog B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fem1b"
      },
      {
        "slug": "fibp",
        "symbol": "FIBP",
        "hgnc": "HGNC:3705",
        "name": "FGF1 intracellular binding protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fibp"
      },
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "galnt2",
        "symbol": "GALNT2",
        "hgnc": "HGNC:4124",
        "name": "polypeptide N-acetylgalactosaminyltransferase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/galnt2"
      },
      {
        "slug": "gatad2b",
        "symbol": "GATAD2B",
        "hgnc": "HGNC:30778",
        "name": "GATA zinc finger domain containing 2B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gatad2b"
      },
      {
        "slug": "grhl2",
        "symbol": "GRHL2",
        "hgnc": "HGNC:2799",
        "name": "grainyhead like transcription factor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grhl2"
      },
      {
        "slug": "gria1",
        "symbol": "GRIA1",
        "hgnc": "HGNC:4571",
        "name": "glutamate ionotropic receptor AMPA type subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gria1"
      },
      {
        "slug": "gtf2e2",
        "symbol": "GTF2E2",
        "hgnc": "HGNC:4651",
        "name": "general transcription factor IIE subunit 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gtf2e2"
      },
      {
        "slug": "gtf2h5",
        "symbol": "GTF2H5",
        "hgnc": "HGNC:21157",
        "name": "general transcription factor IIH subunit 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gtf2h5"
      },
      {
        "slug": "h1-4",
        "symbol": "H1-4",
        "hgnc": "HGNC:4718",
        "name": "H1.4 linker histone, cluster member",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/h1-4"
      },
      {
        "slug": "hk1",
        "symbol": "HK1",
        "hgnc": "HGNC:4922",
        "name": "hexokinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hk1"
      },
      {
        "slug": "ift27",
        "symbol": "IFT27",
        "hgnc": "HGNC:18626",
        "name": "intraflagellar transport 27",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift27"
      },
      {
        "slug": "ift74",
        "symbol": "IFT74",
        "hgnc": "HGNC:21424",
        "name": "intraflagellar transport 74",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift74"
      },
      {
        "slug": "kif11",
        "symbol": "KIF11",
        "hgnc": "HGNC:6388",
        "name": "kinesin family member 11",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif11"
      },
      {
        "slug": "kras",
        "symbol": "KRAS",
        "hgnc": "HGNC:6407",
        "name": "KRas proto-oncogene, GTPase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kras"
      },
      {
        "slug": "lmbrd2",
        "symbol": "LMBRD2",
        "hgnc": "HGNC:25287",
        "name": "LMBR1 domain containing 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmbrd2"
      },
      {
        "slug": "ltbp3",
        "symbol": "LTBP3",
        "hgnc": "HGNC:6716",
        "name": "latent transforming growth factor beta binding protein 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ltbp3"
      },
      {
        "slug": "lztfl1",
        "symbol": "LZTFL1",
        "hgnc": "HGNC:6741",
        "name": "leucine zipper transcription factor like 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lztfl1"
      },
      {
        "slug": "mad2l2",
        "symbol": "MAD2L2",
        "hgnc": "HGNC:6764",
        "name": "mitotic arrest deficient 2 like 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mad2l2"
      },
      {
        "slug": "man2b1",
        "symbol": "MAN2B1",
        "hgnc": "HGNC:6826",
        "name": "mannosidase alpha class 2B member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/man2b1"
      },
      {
        "slug": "map3k7",
        "symbol": "MAP3K7",
        "hgnc": "HGNC:6859",
        "name": "mitogen-activated protein kinase kinase kinase 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k7"
      },
      {
        "slug": "mbtps2",
        "symbol": "MBTPS2",
        "hgnc": "HGNC:15455",
        "name": "membrane bound transcription factor peptidase, site 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mbtps2"
      },
      {
        "slug": "mkks",
        "symbol": "MKKS",
        "hgnc": "HGNC:7108",
        "name": "MKKS centrosomal shuttling protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mkks"
      },
      {
        "slug": "mks1",
        "symbol": "MKS1",
        "hgnc": "HGNC:7121",
        "name": "MKS transition zone complex subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mks1"
      },
      {
        "slug": "mplkip",
        "symbol": "MPLKIP",
        "hgnc": "HGNC:16002",
        "name": "M-phase specific PLK1 interacting protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mplkip"
      },
      {
        "slug": "myt1l",
        "symbol": "MYT1L",
        "hgnc": "HGNC:7623",
        "name": "myelin transcription factor 1 like",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myt1l"
      },
      {
        "slug": "nog",
        "symbol": "NOG",
        "hgnc": "HGNC:7866",
        "name": "noggin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nog"
      },
      {
        "slug": "notch3",
        "symbol": "NOTCH3",
        "hgnc": "HGNC:7883",
        "name": "notch receptor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/notch3"
      },
      {
        "slug": "nphp1",
        "symbol": "NPHP1",
        "hgnc": "HGNC:7905",
        "name": "nephrocystin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nphp1"
      },
      {
        "slug": "nras",
        "symbol": "NRAS",
        "hgnc": "HGNC:7989",
        "name": "NRAS proto-oncogene, GTPase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nras"
      },
      {
        "slug": "otud5",
        "symbol": "OTUD5",
        "hgnc": "HGNC:25402",
        "name": "OTU deubiquitinase 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otud5"
      },
      {
        "slug": "ovol2",
        "symbol": "OVOL2",
        "hgnc": "HGNC:15804",
        "name": "ovo like zinc finger 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ovol2"
      },
      {
        "slug": "pacs2",
        "symbol": "PACS2",
        "hgnc": "HGNC:23794",
        "name": "phosphofurin acidic cluster sorting protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pacs2"
      },
      {
        "slug": "palb2",
        "symbol": "PALB2",
        "hgnc": "HGNC:26144",
        "name": "partner and localizer of BRCA2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/palb2"
      },
      {
        "slug": "pax2",
        "symbol": "PAX2",
        "hgnc": "HGNC:8616",
        "name": "paired box 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pax2"
      },
      {
        "slug": "pbx1",
        "symbol": "PBX1",
        "hgnc": "HGNC:8632",
        "name": "PBX homeobox 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pbx1"
      },
      {
        "slug": "pdzd8",
        "symbol": "PDZD8",
        "hgnc": "HGNC:26974",
        "name": "PDZ domain containing 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pdzd8"
      },
      {
        "slug": "pigt",
        "symbol": "PIGT",
        "hgnc": "HGNC:14938",
        "name": "phosphatidylinositol glycan anchor biosynthesis class T",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigt"
      },
      {
        "slug": "ppfia3",
        "symbol": "PPFIA3",
        "hgnc": "HGNC:9247",
        "name": "PPFI scaffold protein A3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppfia3"
      },
      {
        "slug": "ppp1r12a",
        "symbol": "PPP1R12A",
        "hgnc": "HGNC:7618",
        "name": "protein phosphatase 1 regulatory subunit 12A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp1r12a"
      },
      {
        "slug": "prkar1b",
        "symbol": "PRKAR1B",
        "hgnc": "HGNC:9390",
        "name": "protein kinase cAMP-dependent type I regulatory subunit beta",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkar1b"
      },
      {
        "slug": "ptbp1",
        "symbol": "PTBP1",
        "hgnc": "HGNC:9583",
        "name": "polypyrimidine tract binding protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptbp1"
      },
      {
        "slug": "rad51",
        "symbol": "RAD51",
        "hgnc": "HGNC:9817",
        "name": "RAD51 recombinase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad51"
      },
      {
        "slug": "rad51c",
        "symbol": "RAD51C",
        "hgnc": "HGNC:9820",
        "name": "RAD51 paralog C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad51c"
      },
      {
        "slug": "rap1b",
        "symbol": "RAP1B",
        "hgnc": "HGNC:9857",
        "name": "RAP1B, member of RAS oncogene family",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rap1b"
      },
      {
        "slug": "recql4",
        "symbol": "RECQL4",
        "hgnc": "HGNC:9949",
        "name": "RecQ like helicase 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/recql4"
      },
      {
        "slug": "rfwd3",
        "symbol": "RFWD3",
        "hgnc": "HGNC:25539",
        "name": "ring finger and WD repeat domain 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfwd3"
      },
      {
        "slug": "rhoa",
        "symbol": "RHOA",
        "hgnc": "HGNC:667",
        "name": "ras homolog family member A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rhoa"
      },
      {
        "slug": "rnf113a",
        "symbol": "RNF113A",
        "hgnc": "HGNC:12974",
        "name": "ring finger protein 113A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf113a"
      },
      {
        "slug": "rnu4atac",
        "symbol": "RNU4ATAC",
        "hgnc": "HGNC:34016",
        "name": "RNA, U4atac small nuclear",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4atac"
      },
      {
        "slug": "scaper",
        "symbol": "SCAPER",
        "hgnc": "HGNC:13081",
        "name": "S-phase cyclin A associated protein in the ER",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scaper"
      },
      {
        "slug": "sclt1",
        "symbol": "SCLT1",
        "hgnc": "HGNC:26406",
        "name": "sodium channel and clathrin linker 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sclt1"
      },
      {
        "slug": "scube3",
        "symbol": "SCUBE3",
        "hgnc": "HGNC:13655",
        "name": "signal peptide, CUB domain and EGF like domain containing 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scube3"
      },
      {
        "slug": "sdccag8",
        "symbol": "SDCCAG8",
        "hgnc": "HGNC:10671",
        "name": "SHH signaling and ciliogenesis regulator SDCCAG8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sdccag8"
      },
      {
        "slug": "setbp1",
        "symbol": "SETBP1",
        "hgnc": "HGNC:15573",
        "name": "SET binding protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/setbp1"
      },
      {
        "slug": "sgsm3",
        "symbol": "SGSM3",
        "hgnc": "HGNC:25228",
        "name": "small G protein signaling modulator 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sgsm3"
      },
      {
        "slug": "shoc2",
        "symbol": "SHOC2",
        "hgnc": "HGNC:15454",
        "name": "SHOC2 leucine rich repeat scaffold protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/shoc2"
      },
      {
        "slug": "slc39a8",
        "symbol": "SLC39A8",
        "hgnc": "HGNC:20862",
        "name": "solute carrier family 39 member 8",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc39a8"
      },
      {
        "slug": "slx4",
        "symbol": "SLX4",
        "hgnc": "HGNC:23845",
        "name": "SLX4 structure-specific endonuclease subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slx4"
      },
      {
        "slug": "smg8",
        "symbol": "SMG8",
        "hgnc": "HGNC:25551",
        "name": "SMG8 nonsense mediated mRNA decay factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smg8"
      },
      {
        "slug": "tars1",
        "symbol": "TARS1",
        "hgnc": "HGNC:11572",
        "name": "threonyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tars1"
      },
      {
        "slug": "tbc1d7",
        "symbol": "TBC1D7",
        "hgnc": "HGNC:21066",
        "name": "TBC1 domain family member 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d7"
      },
      {
        "slug": "tbce",
        "symbol": "TBCE",
        "hgnc": "HGNC:11582",
        "name": "tubulin folding cofactor E",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbce"
      },
      {
        "slug": "tnpo2",
        "symbol": "TNPO2",
        "hgnc": "HGNC:19998",
        "name": "transportin 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnpo2"
      },
      {
        "slug": "tra2b",
        "symbol": "TRA2B",
        "hgnc": "HGNC:10781",
        "name": "transformer 2 beta homolog",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tra2b"
      },
      {
        "slug": "trim32",
        "symbol": "TRIM32",
        "hgnc": "HGNC:16380",
        "name": "tripartite motif containing 32",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trim32"
      },
      {
        "slug": "ttc8",
        "symbol": "TTC8",
        "hgnc": "HGNC:20087",
        "name": "tetratricopeptide repeat domain 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc8"
      },
      {
        "slug": "ube2t",
        "symbol": "UBE2T",
        "hgnc": "HGNC:25009",
        "name": "ubiquitin conjugating enzyme E2 T",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube2t"
      },
      {
        "slug": "usp9x",
        "symbol": "USP9X",
        "hgnc": "HGNC:12632",
        "name": "ubiquitin specific peptidase 9 X-linked",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/usp9x"
      },
      {
        "slug": "vsx1",
        "symbol": "VSX1",
        "hgnc": "HGNC:12723",
        "name": "visual system homeobox 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/vsx1"
      },
      {
        "slug": "wdpcp",
        "symbol": "WDPCP",
        "hgnc": "HGNC:28027",
        "name": "WD repeat containing planar cell polarity effector",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdpcp"
      },
      {
        "slug": "xrcc2",
        "symbol": "XRCC2",
        "hgnc": "HGNC:12829",
        "name": "X-ray repair cross complementing 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xrcc2"
      },
      {
        "slug": "yy1",
        "symbol": "YY1",
        "hgnc": "HGNC:12856",
        "name": "YY1 transcription factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/yy1"
      },
      {
        "slug": "zbtb7a",
        "symbol": "ZBTB7A",
        "hgnc": "HGNC:18078",
        "name": "zinc finger and BTB domain containing 7A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zbtb7a"
      },
      {
        "slug": "zeb1",
        "symbol": "ZEB1",
        "hgnc": "HGNC:11642",
        "name": "zinc finger E-box binding homeobox 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zeb1"
      },
      {
        "slug": "zeb2",
        "symbol": "ZEB2",
        "hgnc": "HGNC:14881",
        "name": "zinc finger E-box binding homeobox 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/zeb2"
      },
      {
        "slug": "zfx",
        "symbol": "ZFX",
        "hgnc": "HGNC:12869",
        "name": "zinc finger protein X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfx"
      },
      {
        "slug": "col4a1",
        "symbol": "COL4A1",
        "hgnc": "HGNC:2202",
        "name": "collagen type IV alpha 1 chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a1"
      },
      {
        "slug": "fbxw7",
        "symbol": "FBXW7",
        "hgnc": "HGNC:16712",
        "name": "F-box and WD repeat domain containing 7",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxw7"
      },
      {
        "slug": "mark2",
        "symbol": "MARK2",
        "hgnc": "HGNC:3332",
        "name": "microtubule affinity regulating kinase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mark2"
      },
      {
        "slug": "ppp2r5d",
        "symbol": "PPP2R5D",
        "hgnc": "HGNC:9312",
        "name": "protein phosphatase 2 regulatory subunit B'delta",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp2r5d"
      },
      {
        "slug": "arid1b",
        "symbol": "ARID1B",
        "hgnc": "HGNC:18040",
        "name": "AT-rich interaction domain 1B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arid1b"
      },
      {
        "slug": "cc2d2a",
        "symbol": "CC2D2A",
        "hgnc": "HGNC:29253",
        "name": "coiled-coil and C2 domain containing 2A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cc2d2a"
      },
      {
        "slug": "chd4",
        "symbol": "CHD4",
        "hgnc": "HGNC:1919",
        "name": "chromodomain helicase DNA binding protein 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd4"
      },
      {
        "slug": "chrdl1",
        "symbol": "CHRDL1",
        "hgnc": "HGNC:29861",
        "name": "chordin like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrdl1"
      },
      {
        "slug": "cldn19",
        "symbol": "CLDN19",
        "hgnc": "HGNC:2040",
        "name": "claudin 19",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cldn19"
      },
      {
        "slug": "dnajc21",
        "symbol": "DNAJC21",
        "hgnc": "HGNC:27030",
        "name": "DnaJ heat shock protein family (Hsp40) member C21",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnajc21"
      },
      {
        "slug": "glrb",
        "symbol": "GLRB",
        "hgnc": "HGNC:4329",
        "name": "glycine receptor beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/glrb"
      },
      {
        "slug": "kcnv2",
        "symbol": "KCNV2",
        "hgnc": "HGNC:19698",
        "name": "potassium voltage-gated channel modifier subfamily V member 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnv2"
      },
      {
        "slug": "nipbl",
        "symbol": "NIPBL",
        "hgnc": "HGNC:28862",
        "name": "NIPBL cohesin loading factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nipbl"
      },
      {
        "slug": "piezo2",
        "symbol": "PIEZO2",
        "hgnc": "HGNC:26270",
        "name": "piezo type mechanosensitive ion channel component 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piezo2"
      },
      {
        "slug": "smarcal1",
        "symbol": "SMARCAL1",
        "hgnc": "HGNC:11102",
        "name": "SNF2 related chromatin remodeling annealing helicase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcal1"
      },
      {
        "slug": "tead1",
        "symbol": "TEAD1",
        "hgnc": "HGNC:11714",
        "name": "TEA domain transcription factor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tead1"
      },
      {
        "slug": "trim37",
        "symbol": "TRIM37",
        "hgnc": "HGNC:7523",
        "name": "tripartite motif containing 37",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trim37"
      },
      {
        "slug": "tyr",
        "symbol": "TYR",
        "hgnc": "HGNC:12442",
        "name": "tyrosinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tyr"
      },
      {
        "slug": "ube3b",
        "symbol": "UBE3B",
        "hgnc": "HGNC:13478",
        "name": "ubiquitin protein ligase E3B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube3b"
      },
      {
        "slug": "zmiz1",
        "symbol": "ZMIZ1",
        "hgnc": "HGNC:16493",
        "name": "zinc finger MIZ-type containing 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmiz1"
      }
    ]
  }
}