{
  "url": "https://dantelabs.com/traits/abnormal-st-segment",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-st-segment",
    "id": "HP:0012249",
    "name": "Abnormal ST segment",
    "definition": "An electrocardiographic anomaly of the ST segment, which is the segment that connects the QRS complex and the T wave. The ST segment normally has a duration of 80 to 120 ms, is flat and at the same level (isoelectric) as the PR and TP segment.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-ekg",
        "name": "Abnormal EKG",
        "url": "https://dantelabs.com/traits/abnormal-ekg"
      }
    ],
    "narrower": [
      {
        "slug": "st-segment-elevation",
        "name": "ST segment elevation",
        "genes": 26,
        "url": "https://dantelabs.com/traits/st-segment-elevation"
      },
      {
        "slug": "st-segment-depression",
        "name": "ST segment depression",
        "genes": 13,
        "url": "https://dantelabs.com/traits/st-segment-depression"
      }
    ],
    "genes": [
      {
        "slug": "tnnt2",
        "symbol": "TNNT2",
        "hgnc": "HGNC:11949",
        "name": "troponin T2, cardiac type",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnnt2"
      },
      {
        "slug": "raf1",
        "symbol": "RAF1",
        "hgnc": "HGNC:9829",
        "name": "Raf-1 proto-oncogene, serine/threonine kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/raf1"
      }
    ]
  }
}