{
  "url": "https://dantelabs.com/traits/abnormal-mitochondrial-shape",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-mitochondrial-shape",
    "id": "HP:0012087",
    "name": "Abnormal mitochondrial shape",
    "definition": "An anomaly in the surface contour of mitochondria.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormal-cellular-phenotype",
        "name": "Abnormal cellular phenotype",
        "url": "https://dantelabs.com/traits/abnormal-cellular-phenotype"
      },
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-mitochondrial-morphology",
        "name": "Abnormal mitochondrial morphology",
        "url": "https://dantelabs.com/traits/abnormal-mitochondrial-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "mitochondrial-swelling",
        "name": "Mitochondrial swelling",
        "genes": 4,
        "url": "https://dantelabs.com/traits/mitochondrial-swelling"
      },
      {
        "slug": "elongated-mitochondria",
        "name": "Elongated mitochondria",
        "genes": 2,
        "url": "https://dantelabs.com/traits/elongated-mitochondria"
      },
      {
        "slug": "mitochondrial-hypertrophy",
        "name": "Mitochondrial hypertrophy",
        "genes": 2,
        "url": "https://dantelabs.com/traits/mitochondrial-hypertrophy"
      }
    ],
    "genes": [
      {
        "slug": "fdxr",
        "symbol": "FDXR",
        "hgnc": "HGNC:3642",
        "name": "ferredoxin reductase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fdxr"
      },
      {
        "slug": "mff",
        "symbol": "MFF",
        "hgnc": "HGNC:24858",
        "name": "mitochondrial fission factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mff"
      },
      {
        "slug": "suclg1",
        "symbol": "SUCLG1",
        "hgnc": "HGNC:11449",
        "name": "succinate-CoA ligase GDP/ADP-forming subunit alpha",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/suclg1"
      },
      {
        "slug": "slc25a3",
        "symbol": "SLC25A3",
        "hgnc": "HGNC:10989",
        "name": "solute carrier family 25 member 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc25a3"
      }
    ]
  }
}