{
  "url": "https://dantelabs.com/traits/abnormal-circulating-osteocalcin-level",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-osteocalcin-level",
    "id": "HP:0031427",
    "name": "Abnormal circulating osteocalcin level",
    "definition": "A deviation from the normal concentration of osteocalcin in the blood circulation.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-hormone-concentration",
        "name": "Abnormality of circulating hormone level",
        "url": "https://dantelabs.com/traits/abnormal-circulating-hormone-concentration"
      }
    ],
    "narrower": [
      {
        "slug": "increased-circulating-osteocalcin-level",
        "name": "Increased circulating osteocalcin level",
        "genes": 5,
        "url": "https://dantelabs.com/traits/increased-circulating-osteocalcin-level"
      },
      {
        "slug": "decreased-circulating-osteocalcin-level",
        "name": "Decreased circulating osteocalcin level",
        "genes": 2,
        "url": "https://dantelabs.com/traits/decreased-circulating-osteocalcin-level"
      }
    ],
    "genes": [
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "fn1",
        "symbol": "FN1",
        "hgnc": "HGNC:3778",
        "name": "fibronectin 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fn1"
      }
    ]
  }
}