{
  "url": "https://dantelabs.com/sv/genes/tecrl",
  "gene": {
    "slug": "tecrl",
    "symbol": "TECRL",
    "name": "trans-2,3-enoyl-CoA reductase like",
    "hgnc": "HGNC:27365",
    "summary": null,
    "location": "4q13.1",
    "locusType": "gene with protein product",
    "aliases": [
      "GPSN2L",
      "SRD5A2L2",
      "DKFZp313D0829",
      "DKFZp313B2333",
      "TERL"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000205678",
    "entrezId": 253017,
    "omim": [
      "617242"
    ],
    "uniprot": [
      "Q5HYJ1"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "4",
      "start": 64277702,
      "end": 64409450,
      "strand": "-",
      "ensemblTranscript": "ENST00000381210.8",
      "refseqTranscript": "NM_001010874.5",
      "ensemblProtein": "ENSP00000370607.3",
      "refseqProtein": "NP_001010874.2",
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      ],
      "cds": {
        "start": 64280072,
        "end": 64409351
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    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "4",
      "start": 65140975,
      "end": 65275186,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 63843576,
      "end": 64843575,
      "genes": [],
      "truncated": false
    },
    "reports": [
      {
        "slug": "catecholaminergic-polymorphic-ventricular-tachycardia",
        "name": "Katekolaminerge polymorfa ventrikeltakykardi",
        "diseases": [
          {
            "mondoId": "MONDO:0008648",
            "name": "Familjär ventrikeltakykardi",
            "genes": 7,
            "inheritance": null,
            "description": "En ventrikeltakykardi som orsakas av en ärftlig förändring i individens genom.",
            "management": null,
            "evidence": {
              "gencc": [
                "ClinGen",
                "G2P",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ],
              "actionability": 12
            },
            "sameAsReport": false,
            "broad": false
          },
          {
            "mondoId": "MONDO:0020575",
            "name": "Polymorf ventrikeltakykardi",
            "genes": 7,
            "inheritance": null,
            "description": "En ventrikeltakykardi med oregelbunden frekvens och rytm.",
            "management": null,
            "evidence": {
              "gencc": [
                "ClinGen",
                "G2P",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ],
              "actionability": 12
            },
            "sameAsReport": false,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/sv/conditions/catecholaminergic-polymorphic-ventricular-tachycardia"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "bidirectional-ventricular-tachycardia",
        "name": "Bidirectional ventricular tachycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/bidirectional-ventricular-tachycardia"
      },
      {
        "slug": "premature-ventricular-contraction",
        "name": "Extra heart beat",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/premature-ventricular-contraction"
      },
      {
        "slug": "syncope",
        "name": "Fainting spell",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/syncope"
      },
      {
        "slug": "cardiac-arrest",
        "name": "Heart stops beating",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/cardiac-arrest"
      },
      {
        "slug": "palpitations",
        "name": "Palpitations",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/palpitations"
      },
      {
        "slug": "paroxysmal-ventricular-tachycardia",
        "name": "Paroxysmal ventricular tachycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/paroxysmal-ventricular-tachycardia"
      },
      {
        "slug": "polymorphic-ventricular-tachycardia",
        "name": "Polymorphic ventricular tachycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/polymorphic-ventricular-tachycardia"
      },
      {
        "slug": "prolonged-qt-interval",
        "name": "Prolonged QT interval",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/prolonged-qt-interval"
      },
      {
        "slug": "sudden-death",
        "name": "Sudden death",
        "systems": [
          "constitutional-symptom"
        ],
        "url": "https://dantelabs.com/traits/sudden-death"
      },
      {
        "slug": "ventricular-fibrillation",
        "name": "Ventricular fibrillation",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/ventricular-fibrillation"
      },
      {
        "slug": "ventricular-tachycardia",
        "name": "Ventricular tachycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/ventricular-tachycardia"
      }
    ],
    "related": [
      {
        "slug": "calm1",
        "symbol": "CALM1",
        "name": "calmodulin 1",
        "shared": 2,
        "url": "https://dantelabs.com/sv/genes/calm1"
      },
      {
        "slug": "calm2",
        "symbol": "CALM2",
        "name": "calmodulin 2",
        "shared": 2,
        "url": "https://dantelabs.com/sv/genes/calm2"
      },
      {
        "slug": "calm3",
        "symbol": "CALM3",
        "name": "calmodulin 3",
        "shared": 2,
        "url": "https://dantelabs.com/sv/genes/calm3"
      },
      {
        "slug": "casq2",
        "symbol": "CASQ2",
        "name": "calsequestrin 2",
        "shared": 2,
        "url": "https://dantelabs.com/sv/genes/casq2"
      },
      {
        "slug": "ryr2",
        "symbol": "RYR2",
        "name": "ryanodine receptor 2",
        "shared": 2,
        "url": "https://dantelabs.com/sv/genes/ryr2"
      },
      {
        "slug": "trdn",
        "symbol": "TRDN",
        "name": "triadin",
        "shared": 2,
        "url": "https://dantelabs.com/sv/genes/trdn"
      }
    ],
    "sources": {
      "bundleId": "2026.10.16-c6eea6bf",
      "panel": "2026-10-16",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}