{
  "url": "https://dantelabs.com/sv/genes/sugct",
  "gene": {
    "slug": "sugct",
    "symbol": "SUGCT",
    "name": "succinyl-CoA:glutarate-CoA transferase",
    "hgnc": "HGNC:16001",
    "summary": null,
    "location": "7p14.1",
    "locusType": "gene with protein product",
    "aliases": [
      "FLJ11808",
      "ORF19",
      "DERP13"
    ],
    "previousSymbols": [
      "C7orf10"
    ],
    "ensemblId": "ENSG00000175600",
    "entrezId": 79783,
    "omim": [
      "609187"
    ],
    "uniprot": [
      "Q9HAC7"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "7",
      "start": 40135005,
      "end": 40860763,
      "strand": "+",
      "ensemblTranscript": "ENST00000335693.9",
      "refseqTranscript": "NM_001193313.2",
      "ensemblProtein": "ENSP00000338475.5",
      "refseqProtein": "NP_001180242.2",
      "exons": [
        {
          "start": 40135005,
          "end": 40135120
        },
        {
          "start": 40180947,
          "end": 40180998
        },
        {
          "start": 40181955,
          "end": 40182028
        },
        {
          "start": 40188495,
          "end": 40188580
        },
        {
          "start": 40189544,
          "end": 40189594
        },
        {
          "start": 40194940,
          "end": 40195060
        },
        {
          "start": 40237635,
          "end": 40237726
        },
        {
          "start": 40274513,
          "end": 40274656
        },
        {
          "start": 40316760,
          "end": 40316855
        },
        {
          "start": 40449287,
          "end": 40449358
        },
        {
          "start": 40459101,
          "end": 40459198
        },
        {
          "start": 40496284,
          "end": 40496386
        },
        {
          "start": 40749434,
          "end": 40749497
        },
        {
          "start": 40860316,
          "end": 40860763
        }
      ],
      "cds": {
        "start": 40135021,
        "end": 40860479
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "7",
      "start": 40174575,
      "end": 40900362,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 39409246,
      "end": 41586522,
      "genes": [
        {
          "symbol": "POU6F2",
          "ensemblId": "ENSG00000106536",
          "biotype": "protein_coding",
          "start": 38977909,
          "end": 39493095,
          "strand": "+",
          "slug": "pou6f2"
        },
        {
          "symbol": "YAE1",
          "ensemblId": "ENSG00000241127",
          "biotype": "protein_coding",
          "start": 39566368,
          "end": 39612089,
          "strand": "+",
          "slug": "yae1"
        },
        {
          "symbol": "RALA",
          "ensemblId": "ENSG00000006451",
          "biotype": "protein_coding",
          "start": 39623445,
          "end": 39708217,
          "strand": "+",
          "slug": "rala"
        },
        {
          "symbol": "CDK13",
          "ensemblId": "ENSG00000065883",
          "biotype": "protein_coding",
          "start": 39950013,
          "end": 40099580,
          "strand": "+",
          "slug": "cdk13"
        },
        {
          "symbol": "MPLKIP",
          "ensemblId": "ENSG00000168303",
          "biotype": "protein_coding",
          "start": 40092207,
          "end": 40134877,
          "strand": "-",
          "slug": "mplkip"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-cerebral-white-matter-morphology",
        "name": "Abnormal cerebral white matter morphology",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-cerebral-white-matter-morphology"
      },
      {
        "slug": "abnormal-circulating-enzyme-concentration",
        "name": "Abnormal circulating enzyme concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-circulating-enzyme-concentration"
      },
      {
        "slug": "abnormal-periventricular-white-matter-morphology",
        "name": "Abnormal periventricular white matter morphology",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-periventricular-white-matter-morphology"
      },
      {
        "slug": "diarrhea",
        "name": "Diarrhea",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "url": "https://dantelabs.com/traits/diarrhea"
      },
      {
        "slug": "elevated-circulating-glutaric-acid-concentration",
        "name": "Elevated circulating glutaric acid concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/elevated-circulating-glutaric-acid-concentration"
      },
      {
        "slug": "goiter",
        "name": "Enlarged thyroid gland in neck",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/goiter"
      },
      {
        "slug": "failure-to-thrive",
        "name": "Faltering weight",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/failure-to-thrive"
      },
      {
        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "glutaric-aciduria",
        "name": "Glutaric aciduria",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/glutaric-aciduria"
      },
      {
        "slug": "hypertension",
        "name": "High blood pressure",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "url": "https://dantelabs.com/traits/hypertension"
      },
      {
        "slug": "impulsivity",
        "name": "Impulsivity",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/impulsivity"
      },
      {
        "slug": "ketoacidosis",
        "name": "Ketoacidosis",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ketoacidosis"
      },
      {
        "slug": "ketonuria",
        "name": "Ketonuria",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ketonuria"
      },
      {
        "slug": "lethargy",
        "name": "Lethargy",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/lethargy"
      },
      {
        "slug": "hyperthyroidism",
        "name": "Overactive thyroid",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hyperthyroidism"
      },
      {
        "slug": "reduced-peroxisomal-glutaryl-coa-oxidase-activity",
        "name": "Reduced peroxisomal glutaryl-CoA oxidase activity",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "url": "https://dantelabs.com/traits/reduced-peroxisomal-glutaryl-coa-oxidase-activity"
      },
      {
        "slug": "specific-learning-disability",
        "name": "Specific learning disability",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/specific-learning-disability"
      },
      {
        "slug": "sacral-dimple",
        "name": "Spinal dimple",
        "systems": [
          "abnormality-of-the-integument",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/sacral-dimple"
      },
      {
        "slug": "vomiting",
        "name": "Vomiting",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "url": "https://dantelabs.com/traits/vomiting"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}