{
  "url": "https://dantelabs.com/sv/genes/sra1",
  "gene": {
    "slug": "sra1",
    "symbol": "SRA1",
    "name": "steroid receptor RNA activator 1",
    "hgnc": "HGNC:11281",
    "summary": null,
    "location": "5q31.3",
    "locusType": "gene with protein product",
    "aliases": [
      "SRA",
      "STRAA1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000213523",
    "entrezId": 10011,
    "omim": [
      "603819"
    ],
    "uniprot": [
      "Q9HD15"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "5",
      "start": 140550068,
      "end": 140557473,
      "strand": "-",
      "ensemblTranscript": "ENST00000336283.9",
      "refseqTranscript": "NM_001035235.4",
      "ensemblProtein": "ENSP00000337513.6",
      "refseqProtein": "NP_001030312.3",
      "exons": [
        {
          "start": 140550068,
          "end": 140550911
        },
        {
          "start": 140551061,
          "end": 140551169
        },
        {
          "start": 140551982,
          "end": 140552184
        },
        {
          "start": 140557147,
          "end": 140557272
        },
        {
          "start": 140557428,
          "end": 140557473
        }
      ],
      "cds": {
        "start": 140550700,
        "end": 140557452
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "5",
      "start": 139916925,
      "end": 139937895,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 140053771,
      "end": 141053770,
      "genes": [
        {
          "symbol": "PURA",
          "ensemblId": "ENSG00000185129",
          "biotype": "protein_coding",
          "start": 140107777,
          "end": 140125619,
          "strand": "+",
          "slug": "pura"
        },
        {
          "symbol": "IGIP",
          "ensemblId": "ENSG00000182700",
          "biotype": "protein_coding",
          "start": 140125937,
          "end": 140129392,
          "strand": "+",
          "slug": "igip"
        },
        {
          "symbol": "CYSTM1",
          "ensemblId": "ENSG00000120306",
          "biotype": "protein_coding",
          "start": 140174924,
          "end": 140282212,
          "strand": "+",
          "slug": "cystm1"
        },
        {
          "symbol": "PFDN1",
          "ensemblId": "ENSG00000113068",
          "biotype": "protein_coding",
          "start": 140234986,
          "end": 140303119,
          "strand": "-",
          "slug": "pfdn1"
        },
        {
          "symbol": "HBEGF",
          "ensemblId": "ENSG00000113070",
          "biotype": "protein_coding",
          "start": 140332843,
          "end": 140346614,
          "strand": "-",
          "slug": "hbegf"
        },
        {
          "symbol": "SLC4A9",
          "ensemblId": "ENSG00000113073",
          "biotype": "protein_coding",
          "start": 140360188,
          "end": 140375324,
          "strand": "+",
          "slug": "slc4a9"
        },
        {
          "symbol": "ANKHD1",
          "ensemblId": "ENSG00000131503",
          "biotype": "protein_coding",
          "start": 140401660,
          "end": 140541168,
          "strand": "+",
          "slug": "ankhd1"
        },
        {
          "symbol": "ANKHD1-EIF4EBP3",
          "ensemblId": "ENSG00000254996",
          "biotype": "protein_coding",
          "start": 140401908,
          "end": 140549569,
          "strand": "+",
          "slug": "ankhd1-eif4ebp3"
        },
        {
          "symbol": "EIF4EBP3",
          "ensemblId": "ENSG00000243056",
          "biotype": "protein_coding",
          "start": 140547616,
          "end": 140551708,
          "strand": "+",
          "slug": "eif4ebp3"
        },
        {
          "symbol": "APBB3",
          "ensemblId": "ENSG00000113108",
          "biotype": "protein_coding",
          "start": 140558268,
          "end": 140564781,
          "strand": "-",
          "slug": "apbb3"
        },
        {
          "symbol": "SLC35A4",
          "ensemblId": "ENSG00000176087",
          "biotype": "protein_coding",
          "start": 140564440,
          "end": 140569215,
          "strand": "+",
          "slug": "slc35a4"
        },
        {
          "symbol": "SURMIR",
          "ensemblId": "ENSG00000293600",
          "biotype": "protein_coding",
          "start": 140564440,
          "end": 140569215,
          "strand": "+",
          "slug": "surmir"
        },
        {
          "symbol": "CD14",
          "ensemblId": "ENSG00000170458",
          "biotype": "protein_coding",
          "start": 140630402,
          "end": 140633711,
          "strand": "-",
          "slug": "cd14"
        },
        {
          "symbol": "NDUFA2",
          "ensemblId": "ENSG00000131495",
          "biotype": "protein_coding",
          "start": 140638740,
          "end": 140647823,
          "strand": "-",
          "slug": "ndufa2"
        },
        {
          "symbol": "TMCO6",
          "ensemblId": "ENSG00000113119",
          "biotype": "protein_coding",
          "start": 140639396,
          "end": 140647730,
          "strand": "+",
          "slug": "tmco6"
        },
        {
          "symbol": "IK",
          "ensemblId": "ENSG00000113141",
          "biotype": "protein_coding",
          "start": 140647058,
          "end": 140662480,
          "strand": "+",
          "slug": "ik"
        },
        {
          "symbol": "WDR55",
          "ensemblId": "ENSG00000120314",
          "biotype": "protein_coding",
          "start": 140664476,
          "end": 140674124,
          "strand": "+",
          "slug": "wdr55"
        },
        {
          "symbol": "DND1",
          "ensemblId": "ENSG00000256453",
          "biotype": "protein_coding",
          "start": 140670794,
          "end": 140673576,
          "strand": "-",
          "slug": "dnd1"
        },
        {
          "symbol": "HARS1",
          "ensemblId": "ENSG00000170445",
          "biotype": "protein_coding",
          "start": 140673035,
          "end": 140691537,
          "strand": "-",
          "slug": "hars1"
        },
        {
          "symbol": "HARS2",
          "ensemblId": "ENSG00000112855",
          "biotype": "protein_coding",
          "start": 140691422,
          "end": 140699315,
          "strand": "+",
          "slug": "hars2"
        },
        {
          "symbol": "ZMAT2",
          "ensemblId": "ENSG00000146007",
          "biotype": "protein_coding",
          "start": 140698680,
          "end": 140707729,
          "strand": "+",
          "slug": "zmat2"
        },
        {
          "symbol": "PCDHA1",
          "ensemblId": "ENSG00000204970",
          "biotype": "protein_coding",
          "start": 140786136,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha1"
        },
        {
          "symbol": "PCDHA2",
          "ensemblId": "ENSG00000204969",
          "biotype": "protein_coding",
          "start": 140794845,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha2"
        },
        {
          "symbol": "PCDHA3",
          "ensemblId": "ENSG00000255408",
          "biotype": "protein_coding",
          "start": 140801018,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha3"
        },
        {
          "symbol": "PCDHA4",
          "ensemblId": "ENSG00000204967",
          "biotype": "protein_coding",
          "start": 140807037,
          "end": 141012347,
          "strand": "+",
          "slug": "pcdha4"
        },
        {
          "symbol": "PCDHA5",
          "ensemblId": "ENSG00000204965",
          "biotype": "protein_coding",
          "start": 140821599,
          "end": 141012347,
          "strand": "+",
          "slug": "pcdha5"
        },
        {
          "symbol": "PCDHA6",
          "ensemblId": "ENSG00000081842",
          "biotype": "protein_coding",
          "start": 140827958,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha6"
        },
        {
          "symbol": "PCDHA7",
          "ensemblId": "ENSG00000204963",
          "biotype": "protein_coding",
          "start": 140834231,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha7"
        },
        {
          "symbol": "PCDHA8",
          "ensemblId": "ENSG00000204962",
          "biotype": "protein_coding",
          "start": 140841185,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha8"
        },
        {
          "symbol": "PCDHA9",
          "ensemblId": "ENSG00000204961",
          "biotype": "protein_coding",
          "start": 140847772,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha9"
        },
        {
          "symbol": "PCDHA10",
          "ensemblId": "ENSG00000250120",
          "biotype": "protein_coding",
          "start": 140855883,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha10"
        },
        {
          "symbol": "PCDHA11",
          "ensemblId": "ENSG00000249158",
          "biotype": "protein_coding",
          "start": 140868183,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha11"
        },
        {
          "symbol": "PCDHA12",
          "ensemblId": "ENSG00000251664",
          "biotype": "protein_coding",
          "start": 140875256,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdha12"
        },
        {
          "symbol": "PCDHA13",
          "ensemblId": "ENSG00000239389",
          "biotype": "protein_coding",
          "start": 140882079,
          "end": 141012347,
          "strand": "+",
          "slug": "pcdha13"
        },
        {
          "symbol": "PCDHAC1",
          "ensemblId": "ENSG00000248383",
          "biotype": "protein_coding",
          "start": 140926299,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdhac1"
        },
        {
          "symbol": "PCDHAC2",
          "ensemblId": "ENSG00000243232",
          "biotype": "protein_coding",
          "start": 140966466,
          "end": 141012351,
          "strand": "+",
          "slug": "pcdhac2"
        },
        {
          "symbol": "PCDHB1",
          "ensemblId": "ENSG00000171815",
          "biotype": "protein_coding",
          "start": 141051374,
          "end": 141059346,
          "strand": "+",
          "slug": "pcdhb1"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "decreased-testicular-size",
        "name": "Decreased testicular size",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/decreased-testicular-size"
      },
      {
        "slug": "hypogonadotropic-hypogonadism",
        "name": "Hypogonadotropic hypogonadism",
        "systems": [
          "abnormality-of-the-endocrine-system",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hypogonadotropic-hypogonadism"
      },
      {
        "slug": "infertility",
        "name": "Infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/infertility"
      },
      {
        "slug": "sparse-axillary-hair",
        "name": "Limited armpit hair",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/sparse-axillary-hair"
      },
      {
        "slug": "primary-amenorrhea",
        "name": "Primary amenorrhea",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/primary-amenorrhea"
      },
      {
        "slug": "micropenis",
        "name": "Short penis",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/micropenis"
      },
      {
        "slug": "sparse-pubic-hair",
        "name": "Sparse pubic hair",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/sparse-pubic-hair"
      },
      {
        "slug": "cryptorchidism",
        "name": "Undescended testes",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/cryptorchidism"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}