{
  "url": "https://dantelabs.com/sv/genes/slc26a1",
  "gene": {
    "slug": "slc26a1",
    "symbol": "SLC26A1",
    "name": "solute carrier family 26 member 1",
    "hgnc": "HGNC:10993",
    "summary": null,
    "location": "4p16.3",
    "locusType": "gene with protein product",
    "aliases": [
      "SAT-1",
      "EDM4"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000145217",
    "entrezId": 10861,
    "omim": [
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    ],
    "uniprot": [
      "Q9H2B4"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "4",
      "start": 987657,
      "end": 993404,
      "strand": "-",
      "ensemblTranscript": "ENST00000398516.3",
      "refseqTranscript": "NM_022042.4",
      "ensemblProtein": "ENSP00000381528.2",
      "refseqProtein": "NP_071325.2",
      "exons": [
        {
          "start": 987657,
          "end": 990362
        },
        {
          "start": 991128,
          "end": 991730
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        {
          "start": 993301,
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      ],
      "cds": {
        "start": 988833,
        "end": 991703
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "4",
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      "end": 987228,
      "strand": "-"
    },
    "neighbourhood": {
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      "genes": [
        {
          "symbol": "ZNF721",
          "ensemblId": "ENSG00000182903",
          "biotype": "protein_coding",
          "start": 391179,
          "end": 499159,
          "strand": "-",
          "slug": "znf721"
        },
        {
          "symbol": "PIGG",
          "ensemblId": "ENSG00000174227",
          "biotype": "protein_coding",
          "start": 499195,
          "end": 541173,
          "strand": "+",
          "slug": "pigg"
        },
        {
          "symbol": "TMEM271",
          "ensemblId": "ENSG00000273238",
          "biotype": "protein_coding",
          "start": 573880,
          "end": 576295,
          "strand": "-",
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        {
          "symbol": "PDE6B",
          "ensemblId": "ENSG00000133256",
          "biotype": "protein_coding",
          "start": 625559,
          "end": 670782,
          "strand": "+",
          "slug": "pde6b"
        },
        {
          "symbol": "ATP5ME",
          "ensemblId": "ENSG00000169020",
          "biotype": "protein_coding",
          "start": 672423,
          "end": 674400,
          "strand": "-",
          "slug": "atp5me"
        },
        {
          "symbol": "MYL5",
          "ensemblId": "ENSG00000215375",
          "biotype": "protein_coding",
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          "end": 682033,
          "strand": "+",
          "slug": "myl5"
        },
        {
          "symbol": "SLC49A3",
          "ensemblId": "ENSG00000169026",
          "biotype": "protein_coding",
          "start": 681824,
          "end": 689548,
          "strand": "-",
          "slug": "slc49a3"
        },
        {
          "symbol": "PCGF3",
          "ensemblId": "ENSG00000185619",
          "biotype": "protein_coding",
          "start": 705748,
          "end": 770089,
          "strand": "+",
          "slug": "pcgf3"
        },
        {
          "symbol": "CPLX1",
          "ensemblId": "ENSG00000168993",
          "biotype": "protein_coding",
          "start": 784957,
          "end": 827043,
          "strand": "-",
          "slug": "cplx1"
        },
        {
          "symbol": "GAK",
          "ensemblId": "ENSG00000178950",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "gak"
        },
        {
          "symbol": "TMEM175",
          "ensemblId": "ENSG00000127419",
          "biotype": "protein_coding",
          "start": 932153,
          "end": 958989,
          "strand": "+",
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        },
        {
          "symbol": "DGKQ",
          "ensemblId": "ENSG00000145214",
          "biotype": "protein_coding",
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        },
        {
          "symbol": "IDUA",
          "ensemblId": "ENSG00000127415",
          "biotype": "protein_coding",
          "start": 986997,
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          "strand": "+",
          "slug": "idua"
        },
        {
          "symbol": "FGFRL1",
          "ensemblId": "ENSG00000127418",
          "biotype": "protein_coding",
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          "end": 1026901,
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          "slug": "fgfrl1"
        },
        {
          "symbol": "RNF212",
          "ensemblId": "ENSG00000178222",
          "biotype": "protein_coding",
          "start": 1056247,
          "end": 1113697,
          "strand": "-",
          "slug": "rnf212"
        },
        {
          "symbol": "SPON2",
          "ensemblId": "ENSG00000159674",
          "biotype": "protein_coding",
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          "end": 1208962,
          "strand": "-",
          "slug": "spon2"
        },
        {
          "symbol": "CTBP1",
          "ensemblId": "ENSG00000159692",
          "biotype": "protein_coding",
          "start": 1211434,
          "end": 1250333,
          "strand": "-",
          "slug": "ctbp1"
        },
        {
          "symbol": "MAEA",
          "ensemblId": "ENSG00000090316",
          "biotype": "protein_coding",
          "start": 1289839,
          "end": 1340148,
          "strand": "+",
          "slug": "maea"
        },
        {
          "symbol": "UVSSA",
          "ensemblId": "ENSG00000163945",
          "biotype": "protein_coding",
          "start": 1345691,
          "end": 1395989,
          "strand": "+",
          "slug": "uvssa"
        },
        {
          "symbol": "NKX1-1",
          "ensemblId": "ENSG00000235608",
          "biotype": "protein_coding",
          "start": 1402932,
          "end": 1406442,
          "strand": "-",
          "slug": "nkx1-1"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "acute-kidney-injury",
        "name": "Acute kidney injury",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/acute-kidney-injury"
      },
      {
        "slug": "calcium-oxalate-nephrolithiasis",
        "name": "Calcium oxalate nephrolithiasis",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/calcium-oxalate-nephrolithiasis"
      },
      {
        "slug": "costochondral-pain",
        "name": "Costochondral pain",
        "systems": [
          "abnormality-of-the-musculoskeletal-system",
          "constitutional-symptom"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/costochondral-pain"
      },
      {
        "slug": "decreased-circulating-sulfate-concentration",
        "name": "Decreased circulating sulfate concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/decreased-circulating-sulfate-concentration"
      },
      {
        "slug": "hyperoxaluria",
        "name": "High urine oxalate levels",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hyperoxaluria"
      },
      {
        "slug": "increased-urinary-sulfate",
        "name": "Increased urinary sulfate",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/increased-urinary-sulfate"
      },
      {
        "slug": "kidney-stone",
        "name": "Kidney stone",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/kidney-stone"
      },
      {
        "slug": "ureteropelvic-junction-obstruction",
        "name": "Ureteropelvic junction obstruction",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/ureteropelvic-junction-obstruction"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}