{
  "url": "https://dantelabs.com/sv/genes/plekho2",
  "gene": {
    "slug": "plekho2",
    "symbol": "PLEKHO2",
    "name": "pleckstrin homology domain containing O2",
    "hgnc": "HGNC:30026",
    "summary": null,
    "location": "15q22.31",
    "locusType": "gene with protein product",
    "aliases": [
      "DKFZp761K2312",
      "PP1628",
      "pp9099"
    ],
    "previousSymbols": [
      "PLEKHQ1"
    ],
    "ensemblId": "ENSG00000241839",
    "entrezId": 80301,
    "omim": [],
    "uniprot": [
      "Q8TD55"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "15",
      "start": 64841915,
      "end": 64868002,
      "strand": "+",
      "ensemblTranscript": "ENST00000323544.5",
      "refseqTranscript": "NM_025201.5",
      "ensemblProtein": "ENSP00000326706.4",
      "refseqProtein": "NP_079477.2",
      "exons": [
        {
          "start": 64841915,
          "end": 64842028
        },
        {
          "start": 64848593,
          "end": 64848742
        },
        {
          "start": 64854921,
          "end": 64855037
        },
        {
          "start": 64859894,
          "end": 64859998
        },
        {
          "start": 64861477,
          "end": 64861575
        },
        {
          "start": 64864899,
          "end": 64868002
        }
      ],
      "cds": {
        "start": 64842017,
        "end": 64865888
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "15",
      "start": 65134088,
      "end": 65160206,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 64354959,
      "end": 65354958,
      "genes": [
        {
          "symbol": "CSNK1G1",
          "ensemblId": "ENSG00000169118",
          "biotype": "protein_coding",
          "start": 64165525,
          "end": 64356554,
          "strand": "-",
          "slug": "csnk1g1"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000259316",
          "biotype": "protein_coding",
          "start": 64181180,
          "end": 64381440,
          "strand": "-"
        },
        {
          "symbol": "PCLAF",
          "ensemblId": "ENSG00000166803",
          "biotype": "protein_coding",
          "start": 64364129,
          "end": 64387687,
          "strand": "-",
          "slug": "pclaf"
        },
        {
          "symbol": "TRIP4",
          "ensemblId": "ENSG00000103671",
          "biotype": "protein_coding",
          "start": 64387748,
          "end": 64458653,
          "strand": "+",
          "slug": "trip4"
        },
        {
          "symbol": "ZNF609",
          "ensemblId": "ENSG00000180357",
          "biotype": "protein_coding",
          "start": 64460549,
          "end": 64686068,
          "strand": "+",
          "slug": "znf609"
        },
        {
          "symbol": "OAZ2",
          "ensemblId": "ENSG00000180304",
          "biotype": "protein_coding",
          "start": 64686833,
          "end": 64703281,
          "strand": "-",
          "slug": "oaz2"
        },
        {
          "symbol": "RBPMS2",
          "ensemblId": "ENSG00000166831",
          "biotype": "protein_coding",
          "start": 64739886,
          "end": 64775860,
          "strand": "-",
          "slug": "rbpms2"
        },
        {
          "symbol": "PIF1",
          "ensemblId": "ENSG00000140451",
          "biotype": "protein_coding",
          "start": 64815629,
          "end": 64825677,
          "strand": "-",
          "slug": "pif1"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000249240",
          "biotype": "protein_coding",
          "start": 64841883,
          "end": 64930920,
          "strand": "+"
        },
        {
          "symbol": "ANKDD1A",
          "ensemblId": "ENSG00000166839",
          "biotype": "protein_coding",
          "start": 64911853,
          "end": 64979845,
          "strand": "+",
          "slug": "ankdd1a"
        },
        {
          "symbol": "SPG21",
          "ensemblId": "ENSG00000090487",
          "biotype": "protein_coding",
          "start": 64954566,
          "end": 64990312,
          "strand": "-",
          "slug": "spg21"
        },
        {
          "symbol": "MTFMT",
          "ensemblId": "ENSG00000103707",
          "biotype": "protein_coding",
          "start": 64990829,
          "end": 65029652,
          "strand": "-",
          "slug": "mtfmt"
        },
        {
          "symbol": "SLC51B",
          "ensemblId": "ENSG00000186198",
          "biotype": "protein_coding",
          "start": 65045132,
          "end": 65053397,
          "strand": "+",
          "slug": "slc51b"
        },
        {
          "symbol": "RASL12",
          "ensemblId": "ENSG00000103710",
          "biotype": "protein_coding",
          "start": 65053337,
          "end": 65076690,
          "strand": "-",
          "slug": "rasl12"
        },
        {
          "symbol": "KBTBD13",
          "ensemblId": "ENSG00000234438",
          "biotype": "protein_coding",
          "start": 65076746,
          "end": 65079948,
          "strand": "+",
          "slug": "kbtbd13"
        },
        {
          "symbol": "UBAP1L",
          "ensemblId": "ENSG00000246922",
          "biotype": "protein_coding",
          "start": 65091766,
          "end": 65115200,
          "strand": "-",
          "slug": "ubap1l"
        },
        {
          "symbol": "PDCD7",
          "ensemblId": "ENSG00000090470",
          "biotype": "protein_coding",
          "start": 65117379,
          "end": 65133836,
          "strand": "-",
          "slug": "pdcd7"
        },
        {
          "symbol": "CLPX",
          "ensemblId": "ENSG00000166855",
          "biotype": "protein_coding",
          "start": 65148219,
          "end": 65185643,
          "strand": "-",
          "slug": "clpx"
        },
        {
          "symbol": "CILP",
          "ensemblId": "ENSG00000138615",
          "biotype": "protein_coding",
          "start": 65194760,
          "end": 65211491,
          "strand": "-",
          "slug": "cilp"
        },
        {
          "symbol": "PARP16",
          "ensemblId": "ENSG00000138617",
          "biotype": "protein_coding",
          "start": 65231398,
          "end": 65300618,
          "strand": "-",
          "slug": "parp16"
        },
        {
          "symbol": "IGDCC3",
          "ensemblId": "ENSG00000174498",
          "biotype": "protein_coding",
          "start": 65327127,
          "end": 65378087,
          "strand": "-",
          "slug": "igdcc3"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}