{
  "url": "https://dantelabs.com/sv/genes/ildr1",
  "gene": {
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    "symbol": "ILDR1",
    "name": "immunoglobulin like domain containing receptor 1",
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    "locusType": "gene with protein product",
    "aliases": [
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    "uniprot": [
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    },
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      "strand": "-"
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    "neighbourhood": {
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      "genes": [
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        {
          "symbol": "ARGFX",
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        {
          "symbol": "FBXO40",
          "ensemblId": "ENSG00000163833",
          "biotype": "protein_coding",
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          "strand": "+",
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        {
          "symbol": "HCLS1",
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          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "hcls1"
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        {
          "symbol": "GOLGB1",
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          "biotype": "protein_coding",
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        {
          "symbol": "IQCB1",
          "ensemblId": "ENSG00000173226",
          "biotype": "protein_coding",
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          "slug": "iqcb1"
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        {
          "symbol": "EAF2",
          "ensemblId": "ENSG00000145088",
          "biotype": "protein_coding",
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          "end": 121888073,
          "strand": "+",
          "slug": "eaf2"
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        {
          "symbol": "SLC15A2",
          "ensemblId": "ENSG00000163406",
          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "slc15a2"
        },
        {
          "symbol": "CD86",
          "ensemblId": "ENSG00000114013",
          "biotype": "protein_coding",
          "start": 122055356,
          "end": 122121557,
          "strand": "+",
          "slug": "cd86"
        },
        {
          "symbol": "CASR",
          "ensemblId": "ENSG00000036828",
          "biotype": "protein_coding",
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        {
          "symbol": "CSTA",
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          "biotype": "protein_coding",
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          "end": 122359856,
          "strand": "+",
          "slug": "csta"
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        {
          "symbol": "MIX23",
          "ensemblId": "ENSG00000160124",
          "biotype": "protein_coding",
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          "end": 122383276,
          "strand": "-",
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        },
        {
          "symbol": "FAM162A",
          "ensemblId": "ENSG00000114023",
          "biotype": "protein_coding",
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          "end": 122412334,
          "strand": "+",
          "slug": "fam162a"
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        {
          "symbol": "WDR5B",
          "ensemblId": "ENSG00000196981",
          "biotype": "protein_coding",
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          "end": 122416464,
          "strand": "-",
          "slug": "wdr5b"
        },
        {
          "symbol": "KPNA1",
          "ensemblId": "ENSG00000114030",
          "biotype": "protein_coding",
          "start": 122421902,
          "end": 122514955,
          "strand": "-",
          "slug": "kpna1"
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      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "hearing-loss-and-deafness",
        "name": "Hörselnedsättning och dövhet",
        "diseases": [
          {
            "mondoId": "MONDO:0019497",
            "name": "Icke-syndromisk ärftlig hörselnedsättning",
            "genes": 97,
            "inheritance": null,
            "description": "Ärftlig hörselnedsättning utan andra medicinska symtom, inklusive de vanliga recessiva formerna orsakade av GJB2, OTOF, SLC26A4, STRC och många andra gener, samt dominanta, X-kopplade och mitokondriella former.",
            "management": "Att känna till den genetiska orsaken kan vägleda hörselstöd och beslut om cochleaimplantat, behörighet till studier med genterapi (till exempel OTOF) och familjerådgivning.",
            "evidence": {
              "gencc": [
                "ClinGen",
                "G2P",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ],
              "actionability": 10
            },
            "sameAsReport": false,
            "broad": true
          }
        ],
        "url": "https://dantelabs.com/sv/conditions/hearing-loss-and-deafness"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "sensorineural-hearing-impairment",
        "name": "Sensorineural hearing impairment",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "url": "https://dantelabs.com/traits/sensorineural-hearing-impairment"
      }
    ],
    "related": [
      {
        "slug": "actg1",
        "symbol": "ACTG1",
        "name": "actin gamma 1",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/actg1"
      },
      {
        "slug": "afg2b",
        "symbol": "AFG2B",
        "name": "AAA ATPase AFG2B",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/afg2b"
      },
      {
        "slug": "aifm1",
        "symbol": "AIFM1",
        "name": "apoptosis inducing factor mitochondria associated 1",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/aifm1"
      },
      {
        "slug": "atp11a",
        "symbol": "ATP11A",
        "name": "ATPase phospholipid transporting 11A",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/atp11a"
      },
      {
        "slug": "atp2b2",
        "symbol": "ATP2B2",
        "name": "ATPase plasma membrane Ca2+ transporting 2",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/atp2b2"
      },
      {
        "slug": "cabp2",
        "symbol": "CABP2",
        "name": "calcium binding protein 2",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/cabp2"
      },
      {
        "slug": "cd164",
        "symbol": "CD164",
        "name": "CD164 molecule",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/cd164"
      },
      {
        "slug": "cdc14a",
        "symbol": "CDC14A",
        "name": "cell division cycle 14A",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/cdc14a"
      },
      {
        "slug": "cdh23",
        "symbol": "CDH23",
        "name": "cadherin related 23",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/cdh23"
      },
      {
        "slug": "ceacam16",
        "symbol": "CEACAM16",
        "name": "CEA cell adhesion molecule 16, tectorial membrane component",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/ceacam16"
      },
      {
        "slug": "cib2",
        "symbol": "CIB2",
        "name": "calcium and integrin binding family member 2",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/cib2"
      },
      {
        "slug": "cldn14",
        "symbol": "CLDN14",
        "name": "claudin 14",
        "shared": 1,
        "url": "https://dantelabs.com/sv/genes/cldn14"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}