{
  "url": "https://dantelabs.com/sv/genes/cpn1",
  "gene": {
    "slug": "cpn1",
    "symbol": "CPN1",
    "name": "carboxypeptidase N subunit 1",
    "hgnc": "HGNC:2312",
    "summary": null,
    "location": "10q24.2",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000120054",
    "entrezId": 1369,
    "omim": [
      "603103"
    ],
    "uniprot": [
      "P15169"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "10",
      "start": 100042193,
      "end": 100081869,
      "strand": "-",
      "ensemblTranscript": "ENST00000370418.8",
      "refseqTranscript": "NM_001308.3",
      "ensemblProtein": "ENSP00000359446.3",
      "refseqProtein": "NP_001299.1",
      "exons": [
        {
          "start": 100042193,
          "end": 100042573
        },
        {
          "start": 100048758,
          "end": 100048876
        },
        {
          "start": 100054347,
          "end": 100054446
        },
        {
          "start": 100057013,
          "end": 100057152
        },
        {
          "start": 100063614,
          "end": 100063725
        },
        {
          "start": 100065188,
          "end": 100065370
        },
        {
          "start": 100069714,
          "end": 100069869
        },
        {
          "start": 100075911,
          "end": 100076107
        },
        {
          "start": 100081403,
          "end": 100081869
        }
      ],
      "cds": {
        "start": 100042427,
        "end": 100081625
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "10",
      "start": 101801950,
      "end": 101841634,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 99562031,
      "end": 100562030,
      "genes": [
        {
          "symbol": "SLC25A28",
          "ensemblId": "ENSG00000155287",
          "biotype": "protein_coding",
          "start": 99610509,
          "end": 99622793,
          "strand": "-",
          "slug": "slc25a28"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000285932",
          "biotype": "protein_coding",
          "start": 99651595,
          "end": 99732112,
          "strand": "-"
        },
        {
          "symbol": "ENTPD7",
          "ensemblId": "ENSG00000198018",
          "biotype": "protein_coding",
          "start": 99659415,
          "end": 99712489,
          "strand": "+",
          "slug": "entpd7"
        },
        {
          "symbol": "COX15",
          "ensemblId": "ENSG00000014919",
          "biotype": "protein_coding",
          "start": 99694554,
          "end": 99732858,
          "strand": "-",
          "slug": "cox15"
        },
        {
          "symbol": "CUTC",
          "ensemblId": "ENSG00000119929",
          "biotype": "protein_coding",
          "start": 99702558,
          "end": 99758005,
          "strand": "+",
          "slug": "cutc"
        },
        {
          "symbol": "ABCC2",
          "ensemblId": "ENSG00000023839",
          "biotype": "protein_coding",
          "start": 99782640,
          "end": 99853670,
          "strand": "+",
          "slug": "abcc2"
        },
        {
          "symbol": "DNMBP",
          "ensemblId": "ENSG00000107554",
          "biotype": "protein_coding",
          "start": 99875576,
          "end": 100010049,
          "strand": "-",
          "slug": "dnmbp"
        },
        {
          "symbol": "ERLIN1",
          "ensemblId": "ENSG00000107566",
          "biotype": "protein_coding",
          "start": 100150094,
          "end": 100186062,
          "strand": "-",
          "slug": "erlin1"
        },
        {
          "symbol": "CHUK",
          "ensemblId": "ENSG00000213341",
          "biotype": "protein_coding",
          "start": 100188299,
          "end": 100229611,
          "strand": "-",
          "slug": "chuk"
        },
        {
          "symbol": "CWF19L1",
          "ensemblId": "ENSG00000095485",
          "biotype": "protein_coding",
          "start": 100230024,
          "end": 100267685,
          "strand": "-",
          "slug": "cwf19l1"
        },
        {
          "symbol": "BLOC1S2",
          "ensemblId": "ENSG00000196072",
          "biotype": "protein_coding",
          "start": 100272797,
          "end": 100286708,
          "strand": "-",
          "slug": "bloc1s2"
        },
        {
          "symbol": "PKD2L1",
          "ensemblId": "ENSG00000107593",
          "biotype": "protein_coding",
          "start": 100288149,
          "end": 100330264,
          "strand": "-",
          "slug": "pkd2l1"
        },
        {
          "symbol": "SCD",
          "ensemblId": "ENSG00000099194",
          "biotype": "protein_coding",
          "start": 100346508,
          "end": 100364837,
          "strand": "+",
          "slug": "scd"
        },
        {
          "symbol": "WNT8B",
          "ensemblId": "ENSG00000075290",
          "biotype": "protein_coding",
          "start": 100463009,
          "end": 100483744,
          "strand": "+",
          "slug": "wnt8b"
        },
        {
          "symbol": "SEC31B",
          "ensemblId": "ENSG00000075826",
          "biotype": "protein_coding",
          "start": 100484998,
          "end": 100519892,
          "strand": "-",
          "slug": "sec31b"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000255339",
          "biotype": "protein_coding",
          "start": 100505628,
          "end": 100529881,
          "strand": "-"
        },
        {
          "symbol": "NDUFB8",
          "ensemblId": "ENSG00000166136",
          "biotype": "protein_coding",
          "start": 100523668,
          "end": 100530000,
          "strand": "-",
          "slug": "ndufb8"
        },
        {
          "symbol": "HIF1AN",
          "ensemblId": "ENSG00000166135",
          "biotype": "protein_coding",
          "start": 100529072,
          "end": 100681896,
          "strand": "+",
          "slug": "hif1an"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "angioedema",
        "name": "Angioedema",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/angioedema"
      },
      {
        "slug": "decreased-circulating-carboxypeptidase-n-activity",
        "name": "Decreased circulating carboxypeptidase N activity",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/decreased-circulating-carboxypeptidase-n-activity"
      },
      {
        "slug": "allergic-rhinitis",
        "name": "Hay fever",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-immune-system"
        ],
        "url": "https://dantelabs.com/traits/allergic-rhinitis"
      },
      {
        "slug": "urticaria",
        "name": "Hives",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/urticaria"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}