{
  "url": "https://dantelabs.com/sv/genes/ap2a1",
  "gene": {
    "slug": "ap2a1",
    "symbol": "AP2A1",
    "name": "adaptor related protein complex 2 subunit alpha 1",
    "hgnc": "HGNC:561",
    "summary": null,
    "location": "19q13.33",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [
      "CLAPA1",
      "ADTAA"
    ],
    "ensemblId": "ENSG00000196961",
    "entrezId": 160,
    "omim": [
      "601026"
    ],
    "uniprot": [
      "O95782"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "19",
      "start": 49767001,
      "end": 49807114,
      "strand": "+",
      "ensemblTranscript": "ENST00000354293.10",
      "refseqTranscript": "NM_130787.3",
      "ensemblProtein": "ENSP00000346246.4",
      "refseqProtein": "NP_570603.2",
      "exons": [
        {
          "start": 49767001,
          "end": 49767200
        },
        {
          "start": 49781757,
          "end": 49781825
        },
        {
          "start": 49781947,
          "end": 49782089
        },
        {
          "start": 49782531,
          "end": 49782724
        },
        {
          "start": 49791935,
          "end": 49792064
        },
        {
          "start": 49792991,
          "end": 49793092
        },
        {
          "start": 49795630,
          "end": 49795738
        },
        {
          "start": 49798802,
          "end": 49798952
        },
        {
          "start": 49799327,
          "end": 49799495
        },
        {
          "start": 49799629,
          "end": 49799766
        },
        {
          "start": 49799968,
          "end": 49800150
        },
        {
          "start": 49800961,
          "end": 49801058
        },
        {
          "start": 49801390,
          "end": 49801621
        },
        {
          "start": 49801722,
          "end": 49801889
        },
        {
          "start": 49801981,
          "end": 49802141
        },
        {
          "start": 49802949,
          "end": 49803005
        },
        {
          "start": 49803107,
          "end": 49803189
        },
        {
          "start": 49803287,
          "end": 49803376
        },
        {
          "start": 49805453,
          "end": 49805576
        },
        {
          "start": 49805661,
          "end": 49805777
        },
        {
          "start": 49805872,
          "end": 49805941
        },
        {
          "start": 49806119,
          "end": 49806253
        },
        {
          "start": 49806681,
          "end": 49807114
        }
      ],
      "cds": {
        "start": 49767134,
        "end": 49806758
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "19",
      "start": 50270225,
      "end": 50310370,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 49287058,
      "end": 50287057,
      "genes": [
        {
          "symbol": "SLC6A16",
          "ensemblId": "ENSG00000063127",
          "biotype": "protein_coding",
          "start": 49289638,
          "end": 49325215,
          "strand": "-",
          "slug": "slc6a16"
        },
        {
          "symbol": "CD37",
          "ensemblId": "ENSG00000104894",
          "biotype": "protein_coding",
          "start": 49335171,
          "end": 49343335,
          "strand": "+",
          "slug": "cd37"
        },
        {
          "symbol": "TEAD2",
          "ensemblId": "ENSG00000074219",
          "biotype": "protein_coding",
          "start": 49340389,
          "end": 49362729,
          "strand": "-",
          "slug": "tead2"
        },
        {
          "symbol": "DKKL1",
          "ensemblId": "ENSG00000104901",
          "biotype": "protein_coding",
          "start": 49361783,
          "end": 49375120,
          "strand": "+",
          "slug": "dkkl1"
        },
        {
          "symbol": "KASH5",
          "ensemblId": "ENSG00000161609",
          "biotype": "protein_coding",
          "start": 49388219,
          "end": 49417990,
          "strand": "+",
          "slug": "kash5"
        },
        {
          "symbol": "PTH2",
          "ensemblId": "ENSG00000142538",
          "biotype": "protein_coding",
          "start": 49422419,
          "end": 49423660,
          "strand": "-",
          "slug": "pth2"
        },
        {
          "symbol": "GFY",
          "ensemblId": "ENSG00000261949",
          "biotype": "protein_coding",
          "start": 49423749,
          "end": 49428987,
          "strand": "+",
          "slug": "gfy"
        },
        {
          "symbol": "SLC17A7",
          "ensemblId": "ENSG00000104888",
          "biotype": "protein_coding",
          "start": 49429399,
          "end": 49443197,
          "strand": "-",
          "slug": "slc17a7"
        },
        {
          "symbol": "PIH1D1",
          "ensemblId": "ENSG00000104872",
          "biotype": "protein_coding",
          "start": 49446291,
          "end": 49453537,
          "strand": "-",
          "slug": "pih1d1"
        },
        {
          "symbol": "ALDH16A1",
          "ensemblId": "ENSG00000161618",
          "biotype": "protein_coding",
          "start": 49453146,
          "end": 49471052,
          "strand": "+",
          "slug": "aldh16a1"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000269469",
          "biotype": "protein_coding",
          "start": 49462752,
          "end": 49486231,
          "strand": "+"
        },
        {
          "symbol": "FLT3LG",
          "ensemblId": "ENSG00000090554",
          "biotype": "protein_coding",
          "start": 49474150,
          "end": 49486233,
          "strand": "+",
          "slug": "flt3lg"
        },
        {
          "symbol": "RPL13A",
          "ensemblId": "ENSG00000142541",
          "biotype": "protein_coding",
          "start": 49487510,
          "end": 49493057,
          "strand": "+",
          "slug": "rpl13a"
        },
        {
          "symbol": "RPS11",
          "ensemblId": "ENSG00000142534",
          "biotype": "protein_coding",
          "start": 49496233,
          "end": 49499903,
          "strand": "+",
          "slug": "rps11"
        },
        {
          "symbol": "FCGRT",
          "ensemblId": "ENSG00000104870",
          "biotype": "protein_coding",
          "start": 49506806,
          "end": 49526917,
          "strand": "+",
          "slug": "fcgrt"
        },
        {
          "symbol": "RCN3",
          "ensemblId": "ENSG00000142552",
          "biotype": "protein_coding",
          "start": 49526534,
          "end": 49579703,
          "strand": "+",
          "slug": "rcn3"
        },
        {
          "symbol": "NOSIP",
          "ensemblId": "ENSG00000142546",
          "biotype": "protein_coding",
          "start": 49555207,
          "end": 49592927,
          "strand": "-",
          "slug": "nosip"
        },
        {
          "symbol": "PRRG2",
          "ensemblId": "ENSG00000126460",
          "biotype": "protein_coding",
          "start": 49580646,
          "end": 49591004,
          "strand": "+",
          "slug": "prrg2"
        },
        {
          "symbol": "PRR12",
          "ensemblId": "ENSG00000126464",
          "biotype": "protein_coding",
          "start": 49591108,
          "end": 49626439,
          "strand": "+",
          "slug": "prr12"
        },
        {
          "symbol": "RRAS",
          "ensemblId": "ENSG00000126458",
          "biotype": "protein_coding",
          "start": 49634555,
          "end": 49640211,
          "strand": "-",
          "slug": "rras"
        },
        {
          "symbol": "SCAF1",
          "ensemblId": "ENSG00000126461",
          "biotype": "protein_coding",
          "start": 49640488,
          "end": 49658649,
          "strand": "+",
          "slug": "scaf1"
        },
        {
          "symbol": "IRF3",
          "ensemblId": "ENSG00000126456",
          "biotype": "protein_coding",
          "start": 49659569,
          "end": 49665864,
          "strand": "-",
          "slug": "irf3"
        },
        {
          "symbol": "BCL2L12",
          "ensemblId": "ENSG00000126453",
          "biotype": "protein_coding",
          "start": 49664622,
          "end": 49673917,
          "strand": "+",
          "slug": "bcl2l12"
        },
        {
          "symbol": "PRMT1",
          "ensemblId": "ENSG00000126457",
          "biotype": "protein_coding",
          "start": 49675786,
          "end": 49689029,
          "strand": "+",
          "slug": "prmt1"
        },
        {
          "symbol": "ADM5",
          "ensemblId": "ENSG00000224420",
          "biotype": "protein_coding",
          "start": 49688953,
          "end": 49690575,
          "strand": "+",
          "slug": "adm5"
        },
        {
          "symbol": "CPT1C",
          "ensemblId": "ENSG00000169169",
          "biotype": "protein_coding",
          "start": 49690898,
          "end": 49713733,
          "strand": "+",
          "slug": "cpt1c"
        },
        {
          "symbol": "TSKS",
          "ensemblId": "ENSG00000126467",
          "biotype": "protein_coding",
          "start": 49739753,
          "end": 49763329,
          "strand": "-",
          "slug": "tsks"
        },
        {
          "symbol": "FUZ",
          "ensemblId": "ENSG00000010361",
          "biotype": "protein_coding",
          "start": 49806866,
          "end": 49817376,
          "strand": "-",
          "slug": "fuz"
        },
        {
          "symbol": "MED25",
          "ensemblId": "ENSG00000104973",
          "biotype": "protein_coding",
          "start": 49818269,
          "end": 49840384,
          "strand": "+",
          "slug": "med25"
        },
        {
          "symbol": "PTOV1",
          "ensemblId": "ENSG00000104960",
          "biotype": "protein_coding",
          "start": 49850735,
          "end": 49860744,
          "strand": "+",
          "slug": "ptov1"
        },
        {
          "symbol": "PNKP",
          "ensemblId": "ENSG00000039650",
          "biotype": "protein_coding",
          "start": 49859882,
          "end": 49878351,
          "strand": "-",
          "slug": "pnkp"
        },
        {
          "symbol": "AKT1S1",
          "ensemblId": "ENSG00000204673",
          "biotype": "protein_coding",
          "start": 49869023,
          "end": 49879470,
          "strand": "-",
          "slug": "akt1s1"
        },
        {
          "symbol": "TBC1D17",
          "ensemblId": "ENSG00000104946",
          "biotype": "protein_coding",
          "start": 49877501,
          "end": 49888751,
          "strand": "+",
          "slug": "tbc1d17"
        },
        {
          "symbol": "IL4I1",
          "ensemblId": "ENSG00000104951",
          "biotype": "protein_coding",
          "start": 49889654,
          "end": 49929926,
          "strand": "-",
          "slug": "il4i1"
        },
        {
          "symbol": "NUP62",
          "ensemblId": "ENSG00000213024",
          "biotype": "protein_coding",
          "start": 49906825,
          "end": 49929926,
          "strand": "-",
          "slug": "nup62"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000269179",
          "biotype": "protein_coding",
          "start": 49909501,
          "end": 49958391,
          "strand": "-"
        },
        {
          "symbol": "ATF5",
          "ensemblId": "ENSG00000169136",
          "biotype": "protein_coding",
          "start": 49923910,
          "end": 49933935,
          "strand": "+",
          "slug": "atf5"
        },
        {
          "symbol": "SIGLEC11",
          "ensemblId": "ENSG00000161640",
          "biotype": "protein_coding",
          "start": 49948910,
          "end": 49961172,
          "strand": "-",
          "slug": "siglec11"
        },
        {
          "symbol": "SIGLEC16",
          "ensemblId": "ENSG00000161643",
          "biotype": "protein_coding",
          "start": 49969600,
          "end": 49975819,
          "strand": "+",
          "slug": "siglec16"
        },
        {
          "symbol": "VRK3",
          "ensemblId": "ENSG00000105053",
          "biotype": "protein_coding",
          "start": 49974537,
          "end": 50025946,
          "strand": "-",
          "slug": "vrk3"
        },
        {
          "symbol": "ZNF473",
          "ensemblId": "ENSG00000142528",
          "biotype": "protein_coding",
          "start": 50025714,
          "end": 50053414,
          "strand": "+",
          "slug": "znf473"
        },
        {
          "symbol": "IZUMO2",
          "ensemblId": "ENSG00000161652",
          "biotype": "protein_coding",
          "start": 50152537,
          "end": 50163281,
          "strand": "-",
          "slug": "izumo2"
        },
        {
          "symbol": "MYH14",
          "ensemblId": "ENSG00000105357",
          "biotype": "protein_coding",
          "start": 50188181,
          "end": 50310545,
          "strand": "+",
          "slug": "myh14"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}