{
  "url": "https://dantelabs.com/traits/ventricular-bigeminy",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "ventricular-bigeminy",
    "id": "HP:0034306",
    "name": "Ventricular bigeminy",
    "definition": "An electrocardiographic finding of a normal QRS followed by a premature ventricular contraction; a rhythmic pairing of normal and atypical beats originating in the ventricles in a 1-1 ratio such that an ectopic ventricular beat follows each regular heartbeat.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "premature-ventricular-contraction",
        "name": "Extra heart beat",
        "url": "https://dantelabs.com/traits/premature-ventricular-contraction"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "hcn4",
        "symbol": "HCN4",
        "hgnc": "HGNC:16882",
        "name": "hyperpolarization activated cyclic nucleotide gated potassium channel 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hcn4"
      },
      {
        "slug": "polg2",
        "symbol": "POLG2",
        "hgnc": "HGNC:9180",
        "name": "DNA polymerase gamma 2, accessory subunit",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polg2"
      },
      {
        "slug": "calm2",
        "symbol": "CALM2",
        "hgnc": "HGNC:1445",
        "name": "calmodulin 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/calm2"
      },
      {
        "slug": "ppp1r13l",
        "symbol": "PPP1R13L",
        "hgnc": "HGNC:18838",
        "name": "protein phosphatase 1 regulatory subunit 13 like",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp1r13l"
      }
    ]
  }
}