{
  "url": "https://dantelabs.com/traits/spontaneous-hematomas",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "spontaneous-hematomas",
    "id": "HP:0007420",
    "name": "Spontaneous hematomas",
    "definition": "Spontaneous development of hematomas (hematoma) or bruises without significant trauma.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "subcutaneous-hemorrhage",
        "name": "Bleeding below the skin",
        "url": "https://dantelabs.com/traits/subcutaneous-hemorrhage"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "tnxb",
        "symbol": "TNXB",
        "hgnc": "HGNC:11976",
        "name": "tenascin XB",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnxb"
      },
      {
        "slug": "was",
        "symbol": "WAS",
        "hgnc": "HGNC:12731",
        "name": "WASP actin nucleation promoting factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/was"
      },
      {
        "slug": "cd109",
        "symbol": "CD109",
        "hgnc": "HGNC:21685",
        "name": "CD109 molecule",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd109"
      },
      {
        "slug": "cog8",
        "symbol": "COG8",
        "hgnc": "HGNC:18623",
        "name": "component of oligomeric golgi complex 8",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cog8"
      },
      {
        "slug": "f13a1",
        "symbol": "F13A1",
        "hgnc": "HGNC:3531",
        "name": "coagulation factor XIII A chain",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/f13a1"
      },
      {
        "slug": "f13b",
        "symbol": "F13B",
        "hgnc": "HGNC:3534",
        "name": "coagulation factor XIII B chain",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/f13b"
      },
      {
        "slug": "gp1ba",
        "symbol": "GP1BA",
        "hgnc": "HGNC:4439",
        "name": "glycoprotein Ib platelet subunit alpha",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gp1ba"
      },
      {
        "slug": "gp1bb",
        "symbol": "GP1BB",
        "hgnc": "HGNC:4440",
        "name": "glycoprotein Ib platelet subunit beta",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gp1bb"
      },
      {
        "slug": "gp9",
        "symbol": "GP9",
        "hgnc": "HGNC:4444",
        "name": "glycoprotein IX platelet",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gp9"
      },
      {
        "slug": "itga2",
        "symbol": "ITGA2",
        "hgnc": "HGNC:6137",
        "name": "integrin subunit alpha 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itga2"
      },
      {
        "slug": "itga2b",
        "symbol": "ITGA2B",
        "hgnc": "HGNC:6138",
        "name": "integrin subunit alpha 2b",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/itga2b"
      },
      {
        "slug": "itgb3",
        "symbol": "ITGB3",
        "hgnc": "HGNC:6156",
        "name": "integrin subunit beta 3",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/itgb3"
      },
      {
        "slug": "prkacg",
        "symbol": "PRKACG",
        "hgnc": "HGNC:9382",
        "name": "protein kinase cAMP-activated catalytic subunit gamma",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkacg"
      },
      {
        "slug": "atp7a",
        "symbol": "ATP7A",
        "hgnc": "HGNC:869",
        "name": "ATPase copper transporting alpha",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp7a"
      },
      {
        "slug": "f10",
        "symbol": "F10",
        "hgnc": "HGNC:3528",
        "name": "coagulation factor X",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/f10"
      },
      {
        "slug": "f5",
        "symbol": "F5",
        "hgnc": "HGNC:3542",
        "name": "coagulation factor V",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/f5"
      },
      {
        "slug": "fyb1",
        "symbol": "FYB1",
        "hgnc": "HGNC:4036",
        "name": "FYN binding protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fyb1"
      },
      {
        "slug": "f8",
        "symbol": "F8",
        "hgnc": "HGNC:3546",
        "name": "coagulation factor VIII",
        "frequency": "very-rare",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/f8"
      },
      {
        "slug": "serpine1",
        "symbol": "SERPINE1",
        "hgnc": "HGNC:8583",
        "name": "serpin family E member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/serpine1"
      }
    ]
  }
}