{
  "url": "https://dantelabs.com/traits/shortened-pr-interval",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "shortened-pr-interval",
    "id": "HP:0005165",
    "name": "Shortened PR interval",
    "definition": "Reduced time for the PR interval (beginning of the P wave to the beginning of the QRS complex). In adults, normal values are 120 to 200 ms long.",
    "synonyms": [
      "Electrocardiographic short PR interval",
      "Short P-R interval",
      "Shortened PR interval on EKG"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-pr-interval",
        "name": "Abnormal PR interval",
        "url": "https://dantelabs.com/traits/abnormal-pr-interval"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "prkag2",
        "symbol": "PRKAG2",
        "hgnc": "HGNC:9386",
        "name": "protein kinase AMP-activated non-catalytic subunit gamma 2",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/prkag2"
      },
      {
        "slug": "gaa",
        "symbol": "GAA",
        "hgnc": "HGNC:4065",
        "name": "alpha glucosidase",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gaa"
      },
      {
        "slug": "mtfmt",
        "symbol": "MTFMT",
        "hgnc": "HGNC:29666",
        "name": "mitochondrial methionyl-tRNA formyltransferase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mtfmt"
      },
      {
        "slug": "alpk3",
        "symbol": "ALPK3",
        "hgnc": "HGNC:17574",
        "name": "alpha kinase 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alpk3"
      },
      {
        "slug": "cacna1s",
        "symbol": "CACNA1S",
        "hgnc": "HGNC:1397",
        "name": "calcium voltage-gated channel subunit alpha1 S",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1s"
      },
      {
        "slug": "dohh",
        "symbol": "DOHH",
        "hgnc": "HGNC:28662",
        "name": "deoxyhypusine hydroxylase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dohh"
      },
      {
        "slug": "gabra3",
        "symbol": "GABRA3",
        "hgnc": "HGNC:4077",
        "name": "gamma-aminobutyric acid type A receptor subunit alpha3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabra3"
      },
      {
        "slug": "kcnj18",
        "symbol": "KCNJ18",
        "hgnc": "HGNC:39080",
        "name": "potassium inwardly rectifying channel subfamily J member 18",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj18"
      },
      {
        "slug": "mt-cyb",
        "symbol": "MT-CYB",
        "hgnc": "HGNC:7427",
        "name": "mitochondrially encoded cytochrome b",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-cyb"
      },
      {
        "slug": "trpm4",
        "symbol": "TRPM4",
        "hgnc": "HGNC:17993",
        "name": "transient receptor potential cation channel subfamily M member 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trpm4"
      }
    ]
  }
}