{
  "url": "https://dantelabs.com/traits/proximal-hyperreflexia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "proximal-hyperreflexia",
    "id": "HP:0007054",
    "name": "Proximal hyperreflexia",
    "definition": "Hyperactive stretch reflexes of muscles that move proximal joints (elbow, knee).",
    "synonyms": [
      "Hyperreflexia proximally"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "hyperreflexia",
        "name": "Increased reflexes",
        "url": "https://dantelabs.com/traits/hyperreflexia"
      }
    ],
    "narrower": [
      {
        "slug": "hyperactive-patellar-reflex",
        "name": "Brisk knee jerk",
        "genes": 20,
        "url": "https://dantelabs.com/traits/hyperactive-patellar-reflex"
      }
    ],
    "genes": [
      {
        "slug": "klc2",
        "symbol": "KLC2",
        "hgnc": "HGNC:20716",
        "name": "kinesin light chain 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/klc2"
      },
      {
        "slug": "flrt1",
        "symbol": "FLRT1",
        "hgnc": "HGNC:3760",
        "name": "fibronectin leucine rich transmembrane protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flrt1"
      }
    ]
  }
}