{
  "url": "https://dantelabs.com/traits/parathyroid-hyperplasia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "parathyroid-hyperplasia",
    "id": "HP:0008208",
    "name": "Enlarged parathyroid glands",
    "label": "Parathyroid hyperplasia",
    "definition": "Hyperplasia of the parathyroid gland.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-parathyroid-morphology",
        "name": "Abnormal parathyroid morphology",
        "url": "https://dantelabs.com/traits/abnormal-parathyroid-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "kl",
        "symbol": "KL",
        "hgnc": "HGNC:6344",
        "name": "klotho",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kl"
      },
      {
        "slug": "cdkn1b",
        "symbol": "CDKN1B",
        "hgnc": "HGNC:1785",
        "name": "cyclin dependent kinase inhibitor 1B",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdkn1b"
      },
      {
        "slug": "cdkn2b",
        "symbol": "CDKN2B",
        "hgnc": "HGNC:1788",
        "name": "cyclin dependent kinase inhibitor 2B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdkn2b"
      },
      {
        "slug": "men1",
        "symbol": "MEN1",
        "hgnc": "HGNC:7010",
        "name": "menin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/men1"
      },
      {
        "slug": "ifng",
        "symbol": "IFNG",
        "hgnc": "HGNC:5438",
        "name": "interferon gamma",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifng"
      },
      {
        "slug": "tsc1",
        "symbol": "TSC1",
        "hgnc": "HGNC:12362",
        "name": "TSC complex subunit 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tsc1"
      },
      {
        "slug": "tsc2",
        "symbol": "TSC2",
        "hgnc": "HGNC:12363",
        "name": "TSC complex subunit 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tsc2"
      },
      {
        "slug": "ret",
        "symbol": "RET",
        "hgnc": "HGNC:9967",
        "name": "ret proto-oncogene",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ret"
      }
    ]
  }
}