{
  "url": "https://dantelabs.com/traits/mesiodens",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "mesiodens",
    "id": "HP:0011067",
    "name": "Extra tooth",
    "label": "Mesiodens",
    "definition": "A supernumerary tooth in the midline between the maxillary central incisors.",
    "synonyms": [
      "Median supernumary tooth",
      "Midline supernumary tooth"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "supernumerary-tooth",
        "name": "Extra teeth",
        "url": "https://dantelabs.com/traits/supernumerary-tooth"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "puf60",
        "symbol": "PUF60",
        "hgnc": "HGNC:17042",
        "name": "poly(U) binding splicing factor 60",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/puf60"
      },
      {
        "slug": "camta1",
        "symbol": "CAMTA1",
        "hgnc": "HGNC:18806",
        "name": "calmodulin binding transcription activator 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/camta1"
      },
      {
        "slug": "pou4f1",
        "symbol": "POU4F1",
        "hgnc": "HGNC:9218",
        "name": "POU class 4 homeobox 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pou4f1"
      }
    ]
  }
}