{
  "url": "https://dantelabs.com/traits/increased-serum-estrone",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "increased-serum-estrone",
    "id": "HP:0025139",
    "name": "Increased serum estrone",
    "definition": "An elevation above normal limits of the concentration of estrone in the circulation.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-serum-estrone",
        "name": "Abnormal serum estrone",
        "url": "https://dantelabs.com/traits/abnormal-serum-estrone"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cyp19a1",
        "symbol": "CYP19A1",
        "hgnc": "HGNC:2594",
        "name": "cytochrome P450 family 19 subfamily A member 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp19a1"
      }
    ]
  }
}