{
  "url": "https://dantelabs.com/traits/high-myopia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "high-myopia",
    "id": "HP:0011003",
    "name": "Severe near sightedness",
    "label": "High myopia",
    "definition": "A severe form of myopia with greater than -6.00 diopters.",
    "synonyms": [
      "Severely close sighted",
      "Severely near sighted",
      "Severe myopia",
      "Severe myopia (> -6.00 diopters)"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "myopia",
        "name": "Close sighted",
        "url": "https://dantelabs.com/traits/myopia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "adamts10",
        "symbol": "ADAMTS10",
        "hgnc": "HGNC:13201",
        "name": "ADAM metallopeptidase with thrombospondin type 1 motif 10",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/adamts10"
      },
      {
        "slug": "adamts17",
        "symbol": "ADAMTS17",
        "hgnc": "HGNC:17109",
        "name": "ADAM metallopeptidase with thrombospondin type 1 motif 17",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/adamts17"
      },
      {
        "slug": "amotl1",
        "symbol": "AMOTL1",
        "hgnc": "HGNC:17811",
        "name": "angiomotin like 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/amotl1"
      },
      {
        "slug": "arr3",
        "symbol": "ARR3",
        "hgnc": "HGNC:710",
        "name": "arrestin 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arr3"
      },
      {
        "slug": "cfap20",
        "symbol": "CFAP20",
        "hgnc": "HGNC:29523",
        "name": "cilia and flagella associated protein 20",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap20"
      },
      {
        "slug": "col11a1",
        "symbol": "COL11A1",
        "hgnc": "HGNC:2186",
        "name": "collagen type XI alpha 1 chain",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col11a1"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "col9a2",
        "symbol": "COL9A2",
        "hgnc": "HGNC:2218",
        "name": "collagen type IX alpha 2 chain",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col9a2"
      },
      {
        "slug": "fbn1",
        "symbol": "FBN1",
        "hgnc": "HGNC:3603",
        "name": "fibrillin 1",
        "frequency": "obligate",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/fbn1"
      },
      {
        "slug": "fem1b",
        "symbol": "FEM1B",
        "hgnc": "HGNC:3649",
        "name": "fem-1 homolog B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fem1b"
      },
      {
        "slug": "fsd1l",
        "symbol": "FSD1L",
        "hgnc": "HGNC:13753",
        "name": "fibronectin type III and SPRY domain containing 1 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fsd1l"
      },
      {
        "slug": "gzf1",
        "symbol": "GZF1",
        "hgnc": "HGNC:15808",
        "name": "GDNF inducible zinc finger protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gzf1"
      },
      {
        "slug": "hs6st2",
        "symbol": "HS6ST2",
        "hgnc": "HGNC:19133",
        "name": "heparan sulfate 6-O-sulfotransferase 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hs6st2"
      },
      {
        "slug": "kdm6b",
        "symbol": "KDM6B",
        "hgnc": "HGNC:29012",
        "name": "lysine demethylase 6B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6b"
      },
      {
        "slug": "loxl3",
        "symbol": "LOXL3",
        "hgnc": "HGNC:13869",
        "name": "lysyl oxidase like 3",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/loxl3"
      },
      {
        "slug": "lrit3",
        "symbol": "LRIT3",
        "hgnc": "HGNC:24783",
        "name": "leucine rich repeat, Ig-like and transmembrane domains 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrit3"
      },
      {
        "slug": "lrp2",
        "symbol": "LRP2",
        "hgnc": "HGNC:6694",
        "name": "LDL receptor related protein 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp2"
      },
      {
        "slug": "msl2",
        "symbol": "MSL2",
        "hgnc": "HGNC:25544",
        "name": "MSL complex subunit 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msl2"
      },
      {
        "slug": "nhej1",
        "symbol": "NHEJ1",
        "hgnc": "HGNC:25737",
        "name": "non-homologous end joining factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nhej1"
      },
      {
        "slug": "p4ha2",
        "symbol": "P4HA2",
        "hgnc": "HGNC:8547",
        "name": "prolyl 4-hydroxylase subunit alpha 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/p4ha2"
      },
      {
        "slug": "pak2",
        "symbol": "PAK2",
        "hgnc": "HGNC:8591",
        "name": "p21 (RAC1) activated kinase 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pak2"
      },
      {
        "slug": "pde6h",
        "symbol": "PDE6H",
        "hgnc": "HGNC:8790",
        "name": "phosphodiesterase 6H",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6h"
      },
      {
        "slug": "pnpla6",
        "symbol": "PNPLA6",
        "hgnc": "HGNC:16268",
        "name": "patatin like domain 6, lysophospholipase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnpla6"
      },
      {
        "slug": "polr3b",
        "symbol": "POLR3B",
        "hgnc": "HGNC:30348",
        "name": "RNA polymerase III subunit B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3b"
      },
      {
        "slug": "pomgnt1",
        "symbol": "POMGNT1",
        "hgnc": "HGNC:19139",
        "name": "protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomgnt1"
      },
      {
        "slug": "ppox",
        "symbol": "PPOX",
        "hgnc": "HGNC:9280",
        "name": "protoporphyrinogen oxidase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppox"
      },
      {
        "slug": "primpol",
        "symbol": "PRIMPOL",
        "hgnc": "HGNC:26575",
        "name": "primase and DNA directed polymerase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/primpol"
      },
      {
        "slug": "rab28",
        "symbol": "RAB28",
        "hgnc": "HGNC:9768",
        "name": "RAB28, member RAS oncogene family",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab28"
      },
      {
        "slug": "sco2",
        "symbol": "SCO2",
        "hgnc": "HGNC:10604",
        "name": "synthesis of cytochrome C oxidase 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sco2"
      },
      {
        "slug": "slc39a5",
        "symbol": "SLC39A5",
        "hgnc": "HGNC:20502",
        "name": "solute carrier family 39 member 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc39a5"
      },
      {
        "slug": "slitrk6",
        "symbol": "SLITRK6",
        "hgnc": "HGNC:23503",
        "name": "SLIT and NTRK like family member 6",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slitrk6"
      },
      {
        "slug": "tmem216",
        "symbol": "TMEM216",
        "hgnc": "HGNC:25018",
        "name": "transmembrane protein 216",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem216"
      },
      {
        "slug": "ubap1l",
        "symbol": "UBAP1L",
        "hgnc": "HGNC:40028",
        "name": "ubiquitin associated protein 1 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubap1l"
      },
      {
        "slug": "znf644",
        "symbol": "ZNF644",
        "hgnc": "HGNC:29222",
        "name": "zinc finger protein 644",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf644"
      },
      {
        "slug": "atp6v0a2",
        "symbol": "ATP6V0A2",
        "hgnc": "HGNC:18481",
        "name": "ATPase H+ transporting V0 subunit a2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/atp6v0a2"
      },
      {
        "slug": "atp6v1a",
        "symbol": "ATP6V1A",
        "hgnc": "HGNC:851",
        "name": "ATPase H+ transporting V1 subunit A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1a"
      },
      {
        "slug": "atp6v1e1",
        "symbol": "ATP6V1E1",
        "hgnc": "HGNC:857",
        "name": "ATPase H+ transporting V1 subunit E1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1e1"
      },
      {
        "slug": "col18a1",
        "symbol": "COL18A1",
        "hgnc": "HGNC:2195",
        "name": "collagen type XVIII alpha 1 chain",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col18a1"
      },
      {
        "slug": "col9a1",
        "symbol": "COL9A1",
        "hgnc": "HGNC:2217",
        "name": "collagen type IX alpha 1 chain",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col9a1"
      },
      {
        "slug": "col9a3",
        "symbol": "COL9A3",
        "hgnc": "HGNC:2219",
        "name": "collagen type IX alpha 3 chain",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col9a3"
      },
      {
        "slug": "cpsf1",
        "symbol": "CPSF1",
        "hgnc": "HGNC:2324",
        "name": "cleavage and polyadenylation specific factor 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cpsf1"
      },
      {
        "slug": "hyal2",
        "symbol": "HYAL2",
        "hgnc": "HGNC:5321",
        "name": "hyaluronidase 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hyal2"
      },
      {
        "slug": "ltbp2",
        "symbol": "LTBP2",
        "hgnc": "HGNC:6715",
        "name": "latent transforming growth factor beta binding protein 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ltbp2"
      },
      {
        "slug": "nyx",
        "symbol": "NYX",
        "hgnc": "HGNC:8082",
        "name": "nyctalopin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nyx"
      },
      {
        "slug": "p3h2",
        "symbol": "P3H2",
        "hgnc": "HGNC:19317",
        "name": "prolyl 3-hydroxylase 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/p3h2"
      },
      {
        "slug": "asph",
        "symbol": "ASPH",
        "hgnc": "HGNC:757",
        "name": "aspartate beta-hydroxylase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asph"
      },
      {
        "slug": "dag1",
        "symbol": "DAG1",
        "hgnc": "HGNC:2666",
        "name": "dystroglycan 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dag1"
      },
      {
        "slug": "efemp1",
        "symbol": "EFEMP1",
        "hgnc": "HGNC:3218",
        "name": "EGF-like fibulin extracellular matrix protein 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/efemp1"
      },
      {
        "slug": "efl1",
        "symbol": "EFL1",
        "hgnc": "HGNC:25789",
        "name": "elongation factor like GTPase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/efl1"
      },
      {
        "slug": "elovl4",
        "symbol": "ELOVL4",
        "hgnc": "HGNC:14415",
        "name": "ELOVL fatty acid elongase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elovl4"
      },
      {
        "slug": "exosc2",
        "symbol": "EXOSC2",
        "hgnc": "HGNC:17097",
        "name": "exosome component 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/exosc2"
      },
      {
        "slug": "fzd5",
        "symbol": "FZD5",
        "hgnc": "HGNC:4043",
        "name": "frizzled class receptor 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fzd5"
      },
      {
        "slug": "glra2",
        "symbol": "GLRA2",
        "hgnc": "HGNC:4327",
        "name": "glycine receptor alpha 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/glra2"
      },
      {
        "slug": "ipo8",
        "symbol": "IPO8",
        "hgnc": "HGNC:9853",
        "name": "importin 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ipo8"
      },
      {
        "slug": "irx5",
        "symbol": "IRX5",
        "hgnc": "HGNC:14361",
        "name": "iroquois homeobox 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irx5"
      },
      {
        "slug": "itgav",
        "symbol": "ITGAV",
        "hgnc": "HGNC:6150",
        "name": "integrin subunit alpha V",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itgav"
      },
      {
        "slug": "kat5",
        "symbol": "KAT5",
        "hgnc": "HGNC:5275",
        "name": "lysine acetyltransferase 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kat5"
      },
      {
        "slug": "manf",
        "symbol": "MANF",
        "hgnc": "HGNC:15461",
        "name": "mesencephalic astrocyte derived neurotrophic factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/manf"
      },
      {
        "slug": "mfsd8",
        "symbol": "MFSD8",
        "hgnc": "HGNC:28486",
        "name": "major facilitator superfamily domain containing 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mfsd8"
      },
      {
        "slug": "nfix",
        "symbol": "NFIX",
        "hgnc": "HGNC:7788",
        "name": "nuclear factor I X",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfix"
      },
      {
        "slug": "nmnat1",
        "symbol": "NMNAT1",
        "hgnc": "HGNC:17877",
        "name": "nicotinamide nucleotide adenylyltransferase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nmnat1"
      },
      {
        "slug": "pax2",
        "symbol": "PAX2",
        "hgnc": "HGNC:8616",
        "name": "paired box 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pax2"
      },
      {
        "slug": "prdm5",
        "symbol": "PRDM5",
        "hgnc": "HGNC:9349",
        "name": "PR/SET domain 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdm5"
      },
      {
        "slug": "rin2",
        "symbol": "RIN2",
        "hgnc": "HGNC:18750",
        "name": "Ras and Rab interactor 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rin2"
      },
      {
        "slug": "rp2",
        "symbol": "RP2",
        "hgnc": "HGNC:10274",
        "name": "RP2 activator of ARL3 GTPase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp2"
      },
      {
        "slug": "rpgr",
        "symbol": "RPGR",
        "hgnc": "HGNC:10295",
        "name": "retinitis pigmentosa GTPase regulator",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpgr"
      },
      {
        "slug": "tbc1d32",
        "symbol": "TBC1D32",
        "hgnc": "HGNC:21485",
        "name": "TBC1 domain family member 32",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d32"
      },
      {
        "slug": "ttll5",
        "symbol": "TTLL5",
        "hgnc": "HGNC:19963",
        "name": "tubulin tyrosine ligase like 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttll5"
      },
      {
        "slug": "vps50",
        "symbol": "VPS50",
        "hgnc": "HGNC:25956",
        "name": "VPS50 subunit of EARP/GARPII complex",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps50"
      },
      {
        "slug": "znf408",
        "symbol": "ZNF408",
        "hgnc": "HGNC:20041",
        "name": "zinc finger protein 408",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf408"
      },
      {
        "slug": "znf469",
        "symbol": "ZNF469",
        "hgnc": "HGNC:23216",
        "name": "zinc finger protein 469",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf469"
      },
      {
        "slug": "acbd6",
        "symbol": "ACBD6",
        "hgnc": "HGNC:23339",
        "name": "acyl-CoA binding domain containing 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acbd6"
      },
      {
        "slug": "adamtsl4",
        "symbol": "ADAMTSL4",
        "hgnc": "HGNC:19706",
        "name": "ADAMTS like 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adamtsl4"
      },
      {
        "slug": "asxl1",
        "symbol": "ASXL1",
        "hgnc": "HGNC:18318",
        "name": "ASXL transcriptional regulator 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asxl1"
      },
      {
        "slug": "b4galt1",
        "symbol": "B4GALT1",
        "hgnc": "HGNC:924",
        "name": "beta-1,4-galactosyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/b4galt1"
      },
      {
        "slug": "bap1",
        "symbol": "BAP1",
        "hgnc": "HGNC:950",
        "name": "BRCA1 associated deubiquitinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bap1"
      },
      {
        "slug": "bloc1s3",
        "symbol": "BLOC1S3",
        "hgnc": "HGNC:20914",
        "name": "biogenesis of lysosomal organelles complex 1 subunit 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bloc1s3"
      },
      {
        "slug": "ccnq",
        "symbol": "CCNQ",
        "hgnc": "HGNC:28434",
        "name": "cyclin Q",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccnq"
      },
      {
        "slug": "cln3",
        "symbol": "CLN3",
        "hgnc": "HGNC:2074",
        "name": "CLN3 lysosomal/endosomal transmembrane protein, battenin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cln3"
      },
      {
        "slug": "cox7b",
        "symbol": "COX7B",
        "hgnc": "HGNC:2291",
        "name": "cytochrome c oxidase subunit 7B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cox7b"
      },
      {
        "slug": "cyp1b1",
        "symbol": "CYP1B1",
        "hgnc": "HGNC:2597",
        "name": "cytochrome P450 family 1 subfamily B member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp1b1"
      },
      {
        "slug": "cyp4v2",
        "symbol": "CYP4V2",
        "hgnc": "HGNC:23198",
        "name": "cytochrome P450 family 4 subfamily V member 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp4v2"
      },
      {
        "slug": "dohh",
        "symbol": "DOHH",
        "hgnc": "HGNC:28662",
        "name": "deoxyhypusine hydroxylase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dohh"
      },
      {
        "slug": "dot1l",
        "symbol": "DOT1L",
        "hgnc": "HGNC:24948",
        "name": "DOT1 like histone lysine methyltransferase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dot1l"
      },
      {
        "slug": "dph5",
        "symbol": "DPH5",
        "hgnc": "HGNC:24270",
        "name": "diphthamide biosynthesis 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dph5"
      },
      {
        "slug": "fbxo11",
        "symbol": "FBXO11",
        "hgnc": "HGNC:13590",
        "name": "F-box protein 11",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxo11"
      },
      {
        "slug": "fgfr3",
        "symbol": "FGFR3",
        "hgnc": "HGNC:3690",
        "name": "fibroblast growth factor receptor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr3"
      },
      {
        "slug": "gpr179",
        "symbol": "GPR179",
        "hgnc": "HGNC:31371",
        "name": "G protein-coupled receptor 179",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpr179"
      },
      {
        "slug": "hccs",
        "symbol": "HCCS",
        "hgnc": "HGNC:4837",
        "name": "holocytochrome c synthase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hccs"
      },
      {
        "slug": "herc1",
        "symbol": "HERC1",
        "hgnc": "HGNC:4867",
        "name": "HECT and RLD domain containing E3 ubiquitin protein ligase family member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/herc1"
      },
      {
        "slug": "lamb2",
        "symbol": "LAMB2",
        "hgnc": "HGNC:6487",
        "name": "laminin subunit beta 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lamb2"
      },
      {
        "slug": "maf",
        "symbol": "MAF",
        "hgnc": "HGNC:6776",
        "name": "MAF bZIP transcription factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/maf"
      },
      {
        "slug": "myoc",
        "symbol": "MYOC",
        "hgnc": "HGNC:7610",
        "name": "myocilin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myoc"
      },
      {
        "slug": "ndp",
        "symbol": "NDP",
        "hgnc": "HGNC:7678",
        "name": "norrin cystine knot growth factor NDP",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndp"
      },
      {
        "slug": "ndufb11",
        "symbol": "NDUFB11",
        "hgnc": "HGNC:20372",
        "name": "NADH:ubiquinone oxidoreductase subunit B11",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndufb11"
      },
      {
        "slug": "poc1b",
        "symbol": "POC1B",
        "hgnc": "HGNC:30836",
        "name": "POC1 centriolar protein B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/poc1b"
      },
      {
        "slug": "ptbp1",
        "symbol": "PTBP1",
        "hgnc": "HGNC:9583",
        "name": "polypyrimidine tract binding protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptbp1"
      },
      {
        "slug": "recql4",
        "symbol": "RECQL4",
        "hgnc": "HGNC:9949",
        "name": "RecQ like helicase 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/recql4"
      },
      {
        "slug": "rpl10",
        "symbol": "RPL10",
        "hgnc": "HGNC:10298",
        "name": "ribosomal protein L10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpl10"
      },
      {
        "slug": "tgfbi",
        "symbol": "TGFBI",
        "hgnc": "HGNC:11771",
        "name": "transforming growth factor beta induced",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfbi"
      },
      {
        "slug": "ttr",
        "symbol": "TTR",
        "hgnc": "HGNC:12405",
        "name": "transthyretin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttr"
      },
      {
        "slug": "zfx",
        "symbol": "ZFX",
        "hgnc": "HGNC:12869",
        "name": "zinc finger protein X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfx"
      },
      {
        "slug": "sms",
        "symbol": "SMS",
        "hgnc": "HGNC:11123",
        "name": "spermine synthase",
        "frequency": "very-rare",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sms"
      },
      {
        "slug": "cngb3",
        "symbol": "CNGB3",
        "hgnc": "HGNC:2153",
        "name": "cyclic nucleotide gated channel subunit beta 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cngb3"
      },
      {
        "slug": "col11a2",
        "symbol": "COL11A2",
        "hgnc": "HGNC:2187",
        "name": "collagen type XI alpha 2 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col11a2"
      },
      {
        "slug": "cript",
        "symbol": "CRIPT",
        "hgnc": "HGNC:14312",
        "name": "CXXC repeat containing interactor of PDZ3 domain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cript"
      },
      {
        "slug": "erbb3",
        "symbol": "ERBB3",
        "hgnc": "HGNC:3431",
        "name": "erb-b2 receptor tyrosine kinase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/erbb3"
      },
      {
        "slug": "lrpap1",
        "symbol": "LRPAP1",
        "hgnc": "HGNC:6701",
        "name": "LDL receptor related protein associated protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrpap1"
      },
      {
        "slug": "tbc1d24",
        "symbol": "TBC1D24",
        "hgnc": "HGNC:29203",
        "name": "TBC1 domain family member 24",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d24"
      },
      {
        "slug": "ttc8",
        "symbol": "TTC8",
        "hgnc": "HGNC:20087",
        "name": "tetratricopeptide repeat domain 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc8"
      }
    ]
  }
}