{
  "url": "https://dantelabs.com/traits/hand-paresthesia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hand-paresthesia",
    "id": "HP:0033660",
    "name": "Hand tingling",
    "label": "Hand paresthesia",
    "definition": "Tingling (often referred to as a pins and needles feeling) and numbness in the hand.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "acroparesthesia",
        "name": "Acroparesthesia",
        "url": "https://dantelabs.com/traits/acroparesthesia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "comp",
        "symbol": "COMP",
        "hgnc": "HGNC:2227",
        "name": "cartilage oligomeric matrix protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/comp"
      },
      {
        "slug": "pmp22",
        "symbol": "PMP22",
        "hgnc": "HGNC:9118",
        "name": "peripheral myelin protein 22",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pmp22"
      },
      {
        "slug": "sptlc2",
        "symbol": "SPTLC2",
        "hgnc": "HGNC:11278",
        "name": "serine palmitoyltransferase long chain base subunit 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sptlc2"
      }
    ]
  }
}