{
  "url": "https://dantelabs.com/traits/congenital-hip-dislocation",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "congenital-hip-dislocation",
    "id": "HP:0001374",
    "name": "Dislocated hip since birth",
    "label": "Congenital hip dislocation",
    "synonyms": [
      "Congenital dislocation of the hip",
      "Congenital dislocation of the hips",
      "Congenital hip anomaly",
      "Congenital hip dislocations"
    ],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "hip-dysplasia",
        "name": "Abnormal formation of the hip",
        "url": "https://dantelabs.com/traits/hip-dysplasia"
      },
      {
        "slug": "hip-dislocation",
        "name": "Hip dislocation",
        "url": "https://dantelabs.com/traits/hip-dislocation"
      }
    ],
    "narrower": [
      {
        "slug": "congenital-bilateral-hip-dislocation",
        "name": "Congenital bilateral hip dislocation",
        "genes": 10,
        "url": "https://dantelabs.com/traits/congenital-bilateral-hip-dislocation"
      }
    ],
    "genes": [
      {
        "slug": "ahdc1",
        "symbol": "AHDC1",
        "hgnc": "HGNC:25230",
        "name": "AT-hook DNA binding motif containing 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahdc1"
      },
      {
        "slug": "atp6v0a2",
        "symbol": "ATP6V0A2",
        "hgnc": "HGNC:18481",
        "name": "ATPase H+ transporting V0 subunit a2",
        "frequency": "obligate",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/atp6v0a2"
      },
      {
        "slug": "ecel1",
        "symbol": "ECEL1",
        "hgnc": "HGNC:3147",
        "name": "endothelin converting enzyme like 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ecel1"
      },
      {
        "slug": "kdm6b",
        "symbol": "KDM6B",
        "hgnc": "HGNC:29012",
        "name": "lysine demethylase 6B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6b"
      },
      {
        "slug": "scn4a",
        "symbol": "SCN4A",
        "hgnc": "HGNC:10591",
        "name": "sodium voltage-gated channel alpha subunit 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn4a"
      },
      {
        "slug": "skor2",
        "symbol": "SKOR2",
        "hgnc": "HGNC:32695",
        "name": "SKI family transcriptional corepressor 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/skor2"
      },
      {
        "slug": "tbx15",
        "symbol": "TBX15",
        "hgnc": "HGNC:11594",
        "name": "T-box transcription factor 15",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbx15"
      },
      {
        "slug": "trim33",
        "symbol": "TRIM33",
        "hgnc": "HGNC:16290",
        "name": "tripartite motif containing 33",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trim33"
      },
      {
        "slug": "atp6v1a",
        "symbol": "ATP6V1A",
        "hgnc": "HGNC:851",
        "name": "ATPase H+ transporting V1 subunit A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1a"
      },
      {
        "slug": "atp6v1e1",
        "symbol": "ATP6V1E1",
        "hgnc": "HGNC:857",
        "name": "ATPase H+ transporting V1 subunit E1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1e1"
      },
      {
        "slug": "fhl1",
        "symbol": "FHL1",
        "hgnc": "HGNC:3702",
        "name": "four and a half LIM domains 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fhl1"
      },
      {
        "slug": "fig4",
        "symbol": "FIG4",
        "hgnc": "HGNC:16873",
        "name": "FIG4 phosphoinositide 5-phosphatase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fig4"
      },
      {
        "slug": "gemin4",
        "symbol": "GEMIN4",
        "hgnc": "HGNC:15717",
        "name": "gem nuclear organelle associated protein 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gemin4"
      },
      {
        "slug": "hdac4",
        "symbol": "HDAC4",
        "hgnc": "HGNC:14063",
        "name": "histone deacetylase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hdac4"
      },
      {
        "slug": "iars2",
        "symbol": "IARS2",
        "hgnc": "HGNC:29685",
        "name": "isoleucyl-tRNA synthetase 2, mitochondrial",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/iars2"
      },
      {
        "slug": "lonp1",
        "symbol": "LONP1",
        "hgnc": "HGNC:9479",
        "name": "lon peptidase 1, mitochondrial",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lonp1"
      },
      {
        "slug": "plod1",
        "symbol": "PLOD1",
        "hgnc": "HGNC:9081",
        "name": "procollagen-lysine,2-oxoglutarate 5-dioxygenase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plod1"
      },
      {
        "slug": "pycr1",
        "symbol": "PYCR1",
        "hgnc": "HGNC:9721",
        "name": "pyrroline-5-carboxylate reductase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pycr1"
      },
      {
        "slug": "ryr1",
        "symbol": "RYR1",
        "hgnc": "HGNC:10483",
        "name": "ryanodine receptor 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ryr1"
      },
      {
        "slug": "wnt7a",
        "symbol": "WNT7A",
        "hgnc": "HGNC:12786",
        "name": "Wnt family member 7A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnt7a"
      },
      {
        "slug": "abcc9",
        "symbol": "ABCC9",
        "hgnc": "HGNC:60",
        "name": "ATP binding cassette subfamily C member 9",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcc9"
      },
      {
        "slug": "acta1",
        "symbol": "ACTA1",
        "hgnc": "HGNC:129",
        "name": "actin alpha 1, skeletal muscle",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acta1"
      },
      {
        "slug": "ccdc8",
        "symbol": "CCDC8",
        "hgnc": "HGNC:25367",
        "name": "coiled-coil domain containing 8 subunit of 3M complex",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc8"
      },
      {
        "slug": "chrm3",
        "symbol": "CHRM3",
        "hgnc": "HGNC:1952",
        "name": "cholinergic receptor muscarinic 3",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/chrm3"
      },
      {
        "slug": "clcn3",
        "symbol": "CLCN3",
        "hgnc": "HGNC:2021",
        "name": "Cl-/H+ antiporter 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcn3"
      },
      {
        "slug": "col3a1",
        "symbol": "COL3A1",
        "hgnc": "HGNC:2201",
        "name": "collagen type III alpha 1 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col3a1"
      },
      {
        "slug": "col6a3",
        "symbol": "COL6A3",
        "hgnc": "HGNC:2213",
        "name": "collagen type VI alpha 3 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col6a3"
      },
      {
        "slug": "cul7",
        "symbol": "CUL7",
        "hgnc": "HGNC:21024",
        "name": "cullin 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cul7"
      },
      {
        "slug": "dst",
        "symbol": "DST",
        "hgnc": "HGNC:1090",
        "name": "dystonin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dst"
      },
      {
        "slug": "gpc3",
        "symbol": "GPC3",
        "hgnc": "HGNC:4451",
        "name": "glypican 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpc3"
      },
      {
        "slug": "gpc4",
        "symbol": "GPC4",
        "hgnc": "HGNC:4452",
        "name": "glypican 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpc4"
      },
      {
        "slug": "hacd1",
        "symbol": "HACD1",
        "hgnc": "HGNC:9639",
        "name": "3-hydroxyacyl-CoA dehydratase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hacd1"
      },
      {
        "slug": "itga7",
        "symbol": "ITGA7",
        "hgnc": "HGNC:6143",
        "name": "integrin subunit alpha 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itga7"
      },
      {
        "slug": "kdm6a",
        "symbol": "KDM6A",
        "hgnc": "HGNC:12637",
        "name": "lysine demethylase 6A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6a"
      },
      {
        "slug": "kmt2d",
        "symbol": "KMT2D",
        "hgnc": "HGNC:7133",
        "name": "lysine methyltransferase 2D",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kmt2d"
      },
      {
        "slug": "map3k20",
        "symbol": "MAP3K20",
        "hgnc": "HGNC:17797",
        "name": "mitogen-activated protein kinase kinase kinase 20",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k20"
      },
      {
        "slug": "myl2",
        "symbol": "MYL2",
        "hgnc": "HGNC:7583",
        "name": "myosin light chain 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myl2"
      },
      {
        "slug": "naa10",
        "symbol": "NAA10",
        "hgnc": "HGNC:18704",
        "name": "N-alpha-acetyltransferase 10, NatA catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/naa10"
      },
      {
        "slug": "ngly1",
        "symbol": "NGLY1",
        "hgnc": "HGNC:17646",
        "name": "N-glycanase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ngly1"
      },
      {
        "slug": "nsdhl",
        "symbol": "NSDHL",
        "hgnc": "HGNC:13398",
        "name": "NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsdhl"
      },
      {
        "slug": "obsl1",
        "symbol": "OBSL1",
        "hgnc": "HGNC:29092",
        "name": "obscurin like cytoskeletal adaptor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/obsl1"
      },
      {
        "slug": "pafah1b1",
        "symbol": "PAFAH1B1",
        "hgnc": "HGNC:8574",
        "name": "platelet activating factor acetylhydrolase 1b regulatory subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pafah1b1"
      },
      {
        "slug": "ppp2r5d",
        "symbol": "PPP2R5D",
        "hgnc": "HGNC:9312",
        "name": "protein phosphatase 2 regulatory subunit B'delta",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ppp2r5d"
      },
      {
        "slug": "prdm5",
        "symbol": "PRDM5",
        "hgnc": "HGNC:9349",
        "name": "PR/SET domain 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdm5"
      },
      {
        "slug": "ptrh2",
        "symbol": "PTRH2",
        "hgnc": "HGNC:24265",
        "name": "peptidyl-tRNA hydrolase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptrh2"
      },
      {
        "slug": "puf60",
        "symbol": "PUF60",
        "hgnc": "HGNC:17042",
        "name": "poly(U) binding splicing factor 60",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/puf60"
      },
      {
        "slug": "rbmx",
        "symbol": "RBMX",
        "hgnc": "HGNC:9910",
        "name": "RNA binding motif protein X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbmx"
      },
      {
        "slug": "selenon",
        "symbol": "SELENON",
        "hgnc": "HGNC:15999",
        "name": "selenoprotein N",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/selenon"
      },
      {
        "slug": "tpm2",
        "symbol": "TPM2",
        "hgnc": "HGNC:12011",
        "name": "tropomyosin 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tpm2"
      },
      {
        "slug": "tpm3",
        "symbol": "TPM3",
        "hgnc": "HGNC:12012",
        "name": "tropomyosin 3",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tpm3"
      },
      {
        "slug": "tshz3",
        "symbol": "TSHZ3",
        "hgnc": "HGNC:30700",
        "name": "teashirt zinc finger homeobox 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tshz3"
      },
      {
        "slug": "usp9x",
        "symbol": "USP9X",
        "hgnc": "HGNC:12632",
        "name": "ubiquitin specific peptidase 9 X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp9x"
      },
      {
        "slug": "ywhae",
        "symbol": "YWHAE",
        "hgnc": "HGNC:12851",
        "name": "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ywhae"
      },
      {
        "slug": "zic3",
        "symbol": "ZIC3",
        "hgnc": "HGNC:12874",
        "name": "Zic family zinc finger 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zic3"
      },
      {
        "slug": "znf469",
        "symbol": "ZNF469",
        "hgnc": "HGNC:23216",
        "name": "zinc finger protein 469",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/znf469"
      },
      {
        "slug": "aldh3a2",
        "symbol": "ALDH3A2",
        "hgnc": "HGNC:403",
        "name": "aldehyde dehydrogenase 3 family member A2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh3a2"
      },
      {
        "slug": "col5a2",
        "symbol": "COL5A2",
        "hgnc": "HGNC:2210",
        "name": "collagen type V alpha 2 chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col5a2"
      },
      {
        "slug": "tbcd",
        "symbol": "TBCD",
        "hgnc": "HGNC:11581",
        "name": "tubulin folding cofactor D",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbcd"
      },
      {
        "slug": "aldh18a1",
        "symbol": "ALDH18A1",
        "hgnc": "HGNC:9722",
        "name": "aldehyde dehydrogenase 18 family member A1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh18a1"
      },
      {
        "slug": "bicd2",
        "symbol": "BICD2",
        "hgnc": "HGNC:17208",
        "name": "BICD cargo adaptor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bicd2"
      },
      {
        "slug": "dhodh",
        "symbol": "DHODH",
        "hgnc": "HGNC:2867",
        "name": "dihydroorotate dehydrogenase (quinone)",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhodh"
      },
      {
        "slug": "dnajc21",
        "symbol": "DNAJC21",
        "hgnc": "HGNC:27030",
        "name": "DnaJ heat shock protein family (Hsp40) member C21",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnajc21"
      },
      {
        "slug": "eya1",
        "symbol": "EYA1",
        "hgnc": "HGNC:3519",
        "name": "EYA transcriptional coactivator and phosphatase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eya1"
      },
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "hspg2",
        "symbol": "HSPG2",
        "hgnc": "HGNC:5273",
        "name": "heparan sulfate proteoglycan 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hspg2"
      },
      {
        "slug": "kat6b",
        "symbol": "KAT6B",
        "hgnc": "HGNC:17582",
        "name": "lysine acetyltransferase 6B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kat6b"
      },
      {
        "slug": "kif22",
        "symbol": "KIF22",
        "hgnc": "HGNC:6391",
        "name": "kinesin family member 22",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif22"
      },
      {
        "slug": "lrp1",
        "symbol": "LRP1",
        "hgnc": "HGNC:6692",
        "name": "LDL receptor related protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp1"
      },
      {
        "slug": "map3k7",
        "symbol": "MAP3K7",
        "hgnc": "HGNC:6859",
        "name": "mitogen-activated protein kinase kinase kinase 7",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k7"
      },
      {
        "slug": "mkks",
        "symbol": "MKKS",
        "hgnc": "HGNC:7108",
        "name": "MKKS centrosomal shuttling protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mkks"
      },
      {
        "slug": "piezo2",
        "symbol": "PIEZO2",
        "hgnc": "HGNC:26270",
        "name": "piezo type mechanosensitive ion channel component 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piezo2"
      },
      {
        "slug": "porcn",
        "symbol": "PORCN",
        "hgnc": "HGNC:17652",
        "name": "porcupine O-acyltransferase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/porcn"
      },
      {
        "slug": "recql4",
        "symbol": "RECQL4",
        "hgnc": "HGNC:9949",
        "name": "RecQ like helicase 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/recql4"
      },
      {
        "slug": "six1",
        "symbol": "SIX1",
        "hgnc": "HGNC:10887",
        "name": "SIX homeobox 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/six1"
      },
      {
        "slug": "snrpb",
        "symbol": "SNRPB",
        "hgnc": "HGNC:11153",
        "name": "small nuclear ribonucleoprotein polypeptides B and B1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snrpb"
      },
      {
        "slug": "thra",
        "symbol": "THRA",
        "hgnc": "HGNC:11796",
        "name": "thyroid hormone receptor alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/thra"
      },
      {
        "slug": "ube3b",
        "symbol": "UBE3B",
        "hgnc": "HGNC:13478",
        "name": "ubiquitin protein ligase E3B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube3b"
      }
    ]
  }
}