{
  "url": "https://dantelabs.com/traits/abnormal-biliary-tract-morphology",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "abnormal-biliary-tract-morphology",
    "id": "HP:0012440",
    "name": "Abnormal biliary tract morphology",
    "definition": "A structural abnormality of the biliary tree.",
    "synonyms": [
      "Anomaly of the biliary tract"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "biliary-tract-abnormality",
        "name": "Biliary tract abnormality",
        "url": "https://dantelabs.com/traits/biliary-tract-abnormality"
      }
    ],
    "narrower": [
      {
        "slug": "bile-duct-proliferation",
        "name": "Bile duct proliferation",
        "genes": 24,
        "url": "https://dantelabs.com/traits/bile-duct-proliferation"
      },
      {
        "slug": "cholangitis",
        "name": "Bile duct inflammation",
        "genes": 20,
        "url": "https://dantelabs.com/traits/cholangitis"
      },
      {
        "slug": "biliary-cirrhosis",
        "name": "Biliary cirrhosis",
        "genes": 20,
        "url": "https://dantelabs.com/traits/biliary-cirrhosis"
      },
      {
        "slug": "abnormal-intrahepatic-bile-duct-morphology",
        "name": "Abnormal intrahepatic bile duct morphology",
        "genes": 12,
        "url": "https://dantelabs.com/traits/abnormal-intrahepatic-bile-duct-morphology"
      },
      {
        "slug": "biliary-tract-neoplasm",
        "name": "Biliary tract neoplasm",
        "genes": 6,
        "url": "https://dantelabs.com/traits/biliary-tract-neoplasm"
      },
      {
        "slug": "biliary-atresia",
        "name": "Biliary atresia",
        "genes": 4,
        "url": "https://dantelabs.com/traits/biliary-atresia"
      },
      {
        "slug": "biliary-tract-obstruction",
        "name": "Biliary tract obstruction",
        "genes": 4,
        "url": "https://dantelabs.com/traits/biliary-tract-obstruction"
      },
      {
        "slug": "biliary-hyperplasia",
        "name": "Biliary hyperplasia",
        "genes": 3,
        "url": "https://dantelabs.com/traits/biliary-hyperplasia"
      },
      {
        "slug": "abnormal-ductus-choledochus-morphology",
        "name": "Abnormal ductus choledochus morphology",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-ductus-choledochus-morphology"
      },
      {
        "slug": "ductal-bile-plugs",
        "name": "Ductal bile plugs",
        "genes": 2,
        "url": "https://dantelabs.com/traits/ductal-bile-plugs"
      },
      {
        "slug": "bile-duct-polyp",
        "name": "Bile duct polyp",
        "genes": 1,
        "url": "https://dantelabs.com/traits/bile-duct-polyp"
      },
      {
        "slug": "abnormal-extrahepatic-bile-duct-morphology",
        "name": "Abnormal extrahepatic bile duct morphology",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-extrahepatic-bile-duct-morphology"
      }
    ],
    "genes": [
      {
        "slug": "gpr35",
        "symbol": "GPR35",
        "hgnc": "HGNC:4492",
        "name": "G protein-coupled receptor 35",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpr35"
      },
      {
        "slug": "mst1",
        "symbol": "MST1",
        "hgnc": "HGNC:7380",
        "name": "macrophage stimulating 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mst1"
      },
      {
        "slug": "sema4d",
        "symbol": "SEMA4D",
        "hgnc": "HGNC:10732",
        "name": "semaphorin 4D",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema4d"
      },
      {
        "slug": "tcf4",
        "symbol": "TCF4",
        "hgnc": "HGNC:11634",
        "name": "transcription factor 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tcf4"
      },
      {
        "slug": "gcgr",
        "symbol": "GCGR",
        "hgnc": "HGNC:4192",
        "name": "glucagon receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gcgr"
      },
      {
        "slug": "nphp3",
        "symbol": "NPHP3",
        "hgnc": "HGNC:7907",
        "name": "nephrocystin 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nphp3"
      }
    ]
  }
}