{
  "url": "https://dantelabs.com/ro/genes/tuft1",
  "gene": {
    "slug": "tuft1",
    "symbol": "TUFT1",
    "name": "tuftelin 1",
    "hgnc": "HGNC:12422",
    "summary": null,
    "location": "1q21.3",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000143367",
    "entrezId": 7286,
    "omim": [
      "600087"
    ],
    "uniprot": [
      "Q9NNX1"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "1",
      "start": 151540309,
      "end": 151583583,
      "strand": "+",
      "ensemblTranscript": "ENST00000368849.8",
      "refseqTranscript": "NM_020127.3",
      "ensemblProtein": "ENSP00000357842.3",
      "refseqProtein": "NP_064512.1",
      "exons": [
        {
          "start": 151540309,
          "end": 151540426
        },
        {
          "start": 151562091,
          "end": 151562165
        },
        {
          "start": 151562585,
          "end": 151562686
        },
        {
          "start": 151563904,
          "end": 151563990
        },
        {
          "start": 151564525,
          "end": 151564614
        },
        {
          "start": 151566163,
          "end": 151566228
        },
        {
          "start": 151569657,
          "end": 151569770
        },
        {
          "start": 151574270,
          "end": 151574398
        },
        {
          "start": 151574911,
          "end": 151575005
        },
        {
          "start": 151578721,
          "end": 151578826
        },
        {
          "start": 151579649,
          "end": 151579732
        },
        {
          "start": 151580942,
          "end": 151581042
        },
        {
          "start": 151581644,
          "end": 151583583
        }
      ],
      "cds": {
        "start": 151540367,
        "end": 151581707
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "1",
      "start": 151512781,
      "end": 151556059,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 151061946,
      "end": 152061945,
      "genes": [
        {
          "symbol": "CDC42SE1",
          "ensemblId": "ENSG00000197622",
          "biotype": "protein_coding",
          "start": 151050242,
          "end": 151070325,
          "strand": "-",
          "slug": "cdc42se1"
        },
        {
          "symbol": "MLLT11",
          "ensemblId": "ENSG00000213190",
          "biotype": "protein_coding",
          "start": 151054177,
          "end": 151069544,
          "strand": "+",
          "slug": "mllt11"
        },
        {
          "symbol": "GABPB2",
          "ensemblId": "ENSG00000143458",
          "biotype": "protein_coding",
          "start": 151070514,
          "end": 151130109,
          "strand": "+",
          "slug": "gabpb2"
        },
        {
          "symbol": "SEMA6C",
          "ensemblId": "ENSG00000143434",
          "biotype": "protein_coding",
          "start": 151131685,
          "end": 151147813,
          "strand": "-",
          "slug": "sema6c"
        },
        {
          "symbol": "TIPE2",
          "ensemblId": "ENSG00000163154",
          "biotype": "protein_coding",
          "start": 151156621,
          "end": 151160255,
          "strand": "+",
          "slug": "tipe2"
        },
        {
          "symbol": "SCNM1",
          "ensemblId": "ENSG00000163156",
          "biotype": "protein_coding",
          "start": 151156664,
          "end": 151179006,
          "strand": "+",
          "slug": "scnm1"
        },
        {
          "symbol": "LYSMD1",
          "ensemblId": "ENSG00000163155",
          "biotype": "protein_coding",
          "start": 151159748,
          "end": 151165948,
          "strand": "-",
          "slug": "lysmd1"
        },
        {
          "symbol": "TMOD4",
          "ensemblId": "ENSG00000163157",
          "biotype": "protein_coding",
          "start": 151169984,
          "end": 151176284,
          "strand": "-",
          "slug": "tmod4"
        },
        {
          "symbol": "VPS72",
          "ensemblId": "ENSG00000163159",
          "biotype": "protein_coding",
          "start": 151176304,
          "end": 151195321,
          "strand": "-",
          "slug": "vps72"
        },
        {
          "symbol": "PIP5K1A",
          "ensemblId": "ENSG00000143398",
          "biotype": "protein_coding",
          "start": 151197949,
          "end": 151249538,
          "strand": "+",
          "slug": "pip5k1a"
        },
        {
          "symbol": "PSMD4",
          "ensemblId": "ENSG00000159352",
          "biotype": "protein_coding",
          "start": 151254709,
          "end": 151279502,
          "strand": "+",
          "slug": "psmd4"
        },
        {
          "symbol": "ZNF687",
          "ensemblId": "ENSG00000143373",
          "biotype": "protein_coding",
          "start": 151281502,
          "end": 151292180,
          "strand": "+",
          "slug": "znf687"
        },
        {
          "symbol": "PI4KB",
          "ensemblId": "ENSG00000143393",
          "biotype": "protein_coding",
          "start": 151291792,
          "end": 151328394,
          "strand": "-",
          "slug": "pi4kb"
        },
        {
          "symbol": "RFX5",
          "ensemblId": "ENSG00000143390",
          "biotype": "protein_coding",
          "start": 151340640,
          "end": 151347339,
          "strand": "-",
          "slug": "rfx5"
        },
        {
          "symbol": "SELENBP1",
          "ensemblId": "ENSG00000143416",
          "biotype": "protein_coding",
          "start": 151364157,
          "end": 151372716,
          "strand": "-",
          "slug": "selenbp1"
        },
        {
          "symbol": "PSMB4",
          "ensemblId": "ENSG00000159377",
          "biotype": "protein_coding",
          "start": 151399556,
          "end": 151401941,
          "strand": "+",
          "slug": "psmb4"
        },
        {
          "symbol": "POGZ",
          "ensemblId": "ENSG00000143442",
          "biotype": "protein_coding",
          "start": 151402724,
          "end": 151459511,
          "strand": "-",
          "slug": "pogz"
        },
        {
          "symbol": "CGN",
          "ensemblId": "ENSG00000143375",
          "biotype": "protein_coding",
          "start": 151510139,
          "end": 151538692,
          "strand": "+",
          "slug": "cgn"
        },
        {
          "symbol": "SNX27",
          "ensemblId": "ENSG00000143376",
          "biotype": "protein_coding",
          "start": 151611985,
          "end": 151699091,
          "strand": "+",
          "slug": "snx27"
        },
        {
          "symbol": "CELF3",
          "ensemblId": "ENSG00000159409",
          "biotype": "protein_coding",
          "start": 151700058,
          "end": 151716803,
          "strand": "-",
          "slug": "celf3"
        },
        {
          "symbol": "RIIAD1",
          "ensemblId": "ENSG00000178796",
          "biotype": "protein_coding",
          "start": 151710433,
          "end": 151729805,
          "strand": "+",
          "slug": "riiad1"
        },
        {
          "symbol": "MRPL9",
          "ensemblId": "ENSG00000143436",
          "biotype": "protein_coding",
          "start": 151759643,
          "end": 151763522,
          "strand": "-",
          "slug": "mrpl9"
        },
        {
          "symbol": "OAZ3",
          "ensemblId": "ENSG00000143450",
          "biotype": "protein_coding",
          "start": 151762899,
          "end": 151771334,
          "strand": "+",
          "slug": "oaz3"
        },
        {
          "symbol": "TDRKH",
          "ensemblId": "ENSG00000182134",
          "biotype": "protein_coding",
          "start": 151769799,
          "end": 151791416,
          "strand": "-",
          "slug": "tdrkh"
        },
        {
          "symbol": "LINGO4",
          "ensemblId": "ENSG00000213171",
          "biotype": "protein_coding",
          "start": 151800264,
          "end": 151805419,
          "strand": "-",
          "slug": "lingo4"
        },
        {
          "symbol": "RORC",
          "ensemblId": "ENSG00000143365",
          "biotype": "protein_coding",
          "start": 151806021,
          "end": 151831845,
          "strand": "-",
          "slug": "rorc"
        },
        {
          "symbol": "C2CD4D",
          "ensemblId": "ENSG00000225556",
          "biotype": "protein_coding",
          "start": 151837818,
          "end": 151840557,
          "strand": "-",
          "slug": "c2cd4d"
        },
        {
          "symbol": "THEM5",
          "ensemblId": "ENSG00000196407",
          "biotype": "protein_coding",
          "start": 151847101,
          "end": 151853712,
          "strand": "-",
          "slug": "them5"
        },
        {
          "symbol": "THEM4",
          "ensemblId": "ENSG00000159445",
          "biotype": "protein_coding",
          "start": 151870866,
          "end": 151909879,
          "strand": "-",
          "slug": "them4"
        },
        {
          "symbol": "S100A10",
          "ensemblId": "ENSG00000197747",
          "biotype": "protein_coding",
          "start": 151981697,
          "end": 151993891,
          "strand": "-",
          "slug": "s100a10"
        },
        {
          "symbol": "S100A11",
          "ensemblId": "ENSG00000163191",
          "biotype": "protein_coding",
          "start": 152032504,
          "end": 152047907,
          "strand": "-",
          "slug": "s100a11"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "acantholysis",
        "name": "Acantholysis",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/acantholysis"
      },
      {
        "slug": "woolly-hair",
        "name": "Afro-textured hair",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/woolly-hair"
      },
      {
        "slug": "keratosis-pilaris",
        "name": "Chicken skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/keratosis-pilaris"
      },
      {
        "slug": "fragile-skin",
        "name": "Fragile skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/fragile-skin"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}