{
  "url": "https://dantelabs.com/ro/genes/tnfrsf10a",
  "gene": {
    "slug": "tnfrsf10a",
    "symbol": "TNFRSF10A",
    "name": "TNF receptor superfamily member 10a",
    "hgnc": "HGNC:11904",
    "summary": null,
    "location": "8p21.3",
    "locusType": "gene with protein product",
    "aliases": [
      "DR4",
      "Apo2",
      "TRAILR-1",
      "CD261",
      "TRAILR1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000104689",
    "entrezId": 8797,
    "omim": [
      "603611"
    ],
    "uniprot": [
      "O00220"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "8",
      "start": 23190452,
      "end": 23225102,
      "strand": "-",
      "ensemblTranscript": "ENST00000221132.8",
      "refseqTranscript": "NM_003844.4",
      "ensemblProtein": "ENSP00000221132.3",
      "refseqProtein": "NP_003835.3",
      "exons": [
        {
          "start": 23190452,
          "end": 23192013
        },
        {
          "start": 23197132,
          "end": 23197204
        },
        {
          "start": 23199266,
          "end": 23199448
        },
        {
          "start": 23199886,
          "end": 23199917
        },
        {
          "start": 23200505,
          "end": 23200600
        },
        {
          "start": 23200687,
          "end": 23200760
        },
        {
          "start": 23201808,
          "end": 23201919
        },
        {
          "start": 23202648,
          "end": 23202761
        },
        {
          "start": 23212116,
          "end": 23212212
        },
        {
          "start": 23224756,
          "end": 23225102
        }
      ],
      "cds": {
        "start": 23191694,
        "end": 23225061
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "8",
      "start": 23047965,
      "end": 23082639,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 22707777,
      "end": 23707776,
      "genes": [
        {
          "symbol": "PEBP4",
          "ensemblId": "ENSG00000134020",
          "biotype": "protein_coding",
          "start": 22710102,
          "end": 23000000,
          "strand": "-",
          "slug": "pebp4"
        },
        {
          "symbol": "RHOBTB2",
          "ensemblId": "ENSG00000008853",
          "biotype": "protein_coding",
          "start": 22987222,
          "end": 23020723,
          "strand": "+",
          "slug": "rhobtb2"
        },
        {
          "symbol": "TNFRSF10B",
          "ensemblId": "ENSG00000120889",
          "biotype": "protein_coding",
          "start": 23020133,
          "end": 23069121,
          "strand": "-",
          "slug": "tnfrsf10b"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000284956",
          "biotype": "protein_coding",
          "start": 23084403,
          "end": 23115536,
          "strand": "+"
        },
        {
          "symbol": "TNFRSF10C",
          "ensemblId": "ENSG00000173535",
          "biotype": "protein_coding",
          "start": 23102921,
          "end": 23122014,
          "strand": "+",
          "slug": "tnfrsf10c"
        },
        {
          "symbol": "TNFRSF10D",
          "ensemblId": "ENSG00000173530",
          "biotype": "protein_coding",
          "start": 23135588,
          "end": 23164030,
          "strand": "-",
          "slug": "tnfrsf10d"
        },
        {
          "symbol": "CHMP7",
          "ensemblId": "ENSG00000147457",
          "biotype": "protein_coding",
          "start": 23243630,
          "end": 23266156,
          "strand": "+",
          "slug": "chmp7"
        },
        {
          "symbol": "R3HCC1",
          "ensemblId": "ENSG00000104679",
          "biotype": "protein_coding",
          "start": 23270120,
          "end": 23296279,
          "strand": "+",
          "slug": "r3hcc1"
        },
        {
          "symbol": "LOXL2",
          "ensemblId": "ENSG00000134013",
          "biotype": "protein_coding",
          "start": 23296897,
          "end": 23425328,
          "strand": "-",
          "slug": "loxl2"
        },
        {
          "symbol": "ENTPD4",
          "ensemblId": "ENSG00000197217",
          "biotype": "protein_coding",
          "start": 23385783,
          "end": 23457722,
          "strand": "-",
          "slug": "entpd4"
        },
        {
          "symbol": "SLC25A37",
          "ensemblId": "ENSG00000147454",
          "biotype": "protein_coding",
          "start": 23528859,
          "end": 23654350,
          "strand": "+",
          "slug": "slc25a37"
        },
        {
          "symbol": "NKX3-1",
          "ensemblId": "ENSG00000167034",
          "biotype": "protein_coding",
          "start": 23678697,
          "end": 23682953,
          "strand": "-",
          "slug": "nkx3-1"
        },
        {
          "symbol": "NKX2-6",
          "ensemblId": "ENSG00000180053",
          "biotype": "protein_coding",
          "start": 23701740,
          "end": 23706756,
          "strand": "-",
          "slug": "nkx2-6"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}