{
  "url": "https://dantelabs.com/ro/genes/spire1",
  "gene": {
    "slug": "spire1",
    "symbol": "SPIRE1",
    "name": "spire type actin nucleation factor 1",
    "hgnc": "HGNC:30622",
    "summary": null,
    "location": "18p11.21",
    "locusType": "gene with protein product",
    "aliases": [
      "spir-1",
      "KIAA1135"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000134278",
    "entrezId": 56907,
    "omim": [
      "609216"
    ],
    "uniprot": [
      "Q08AE8"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "18",
      "start": 12446512,
      "end": 12658107,
      "strand": "-",
      "ensemblTranscript": "ENST00000409402.9",
      "refseqTranscript": "NM_001128626.2",
      "ensemblProtein": "ENSP00000387266.3",
      "refseqProtein": "NP_001122098.1",
      "exons": [
        {
          "start": 12446512,
          "end": 12449896
        },
        {
          "start": 12452255,
          "end": 12452391
        },
        {
          "start": 12452485,
          "end": 12452512
        },
        {
          "start": 12453068,
          "end": 12453138
        },
        {
          "start": 12454346,
          "end": 12454483
        },
        {
          "start": 12463351,
          "end": 12463493
        },
        {
          "start": 12464868,
          "end": 12464958
        },
        {
          "start": 12479699,
          "end": 12479871
        },
        {
          "start": 12485959,
          "end": 12486000
        },
        {
          "start": 12493072,
          "end": 12493201
        },
        {
          "start": 12496016,
          "end": 12496102
        },
        {
          "start": 12506477,
          "end": 12506641
        },
        {
          "start": 12512454,
          "end": 12512531
        },
        {
          "start": 12535476,
          "end": 12535601
        },
        {
          "start": 12546674,
          "end": 12546904
        },
        {
          "start": 12635062,
          "end": 12635096
        },
        {
          "start": 12657530,
          "end": 12658107
        }
      ],
      "cds": {
        "start": 12449638,
        "end": 12657866
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "18",
      "start": 12446511,
      "end": 12658133,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 12052310,
      "end": 13052309,
      "genes": [
        {
          "symbol": "ANKRD62",
          "ensemblId": "ENSG00000181626",
          "biotype": "protein_coding",
          "start": 12093729,
          "end": 12129764,
          "strand": "+",
          "slug": "ankrd62"
        },
        {
          "symbol": "CIDEA",
          "ensemblId": "ENSG00000176194",
          "biotype": "protein_coding",
          "start": 12254165,
          "end": 12277595,
          "strand": "+",
          "slug": "cidea"
        },
        {
          "symbol": "TUBB6",
          "ensemblId": "ENSG00000176014",
          "biotype": "protein_coding",
          "start": 12307287,
          "end": 12345784,
          "strand": "+",
          "slug": "tubb6"
        },
        {
          "symbol": "AFG3L2",
          "ensemblId": "ENSG00000141385",
          "biotype": "protein_coding",
          "start": 12328871,
          "end": 12377473,
          "strand": "-",
          "slug": "afg3l2"
        },
        {
          "symbol": "PRELID3A",
          "ensemblId": "ENSG00000141391",
          "biotype": "protein_coding",
          "start": 12407896,
          "end": 12432254,
          "strand": "+",
          "slug": "prelid3a"
        },
        {
          "symbol": "PSMG2",
          "ensemblId": "ENSG00000128789",
          "biotype": "protein_coding",
          "start": 12658043,
          "end": 12728945,
          "strand": "+",
          "slug": "psmg2"
        },
        {
          "symbol": "CEP76",
          "ensemblId": "ENSG00000101624",
          "biotype": "protein_coding",
          "start": 12660738,
          "end": 12702777,
          "strand": "-",
          "slug": "cep76"
        },
        {
          "symbol": "PTPN2",
          "ensemblId": "ENSG00000175354",
          "biotype": "protein_coding",
          "start": 12785478,
          "end": 12929643,
          "strand": "-",
          "slug": "ptpn2"
        },
        {
          "symbol": "SEH1L",
          "ensemblId": "ENSG00000085415",
          "biotype": "protein_coding",
          "start": 12947133,
          "end": 12987713,
          "strand": "+",
          "slug": "seh1l"
        },
        {
          "symbol": "CEP192",
          "ensemblId": "ENSG00000101639",
          "biotype": "protein_coding",
          "start": 12991283,
          "end": 13125053,
          "strand": "+",
          "slug": "cep192"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}