{
  "url": "https://dantelabs.com/ro/genes/cyp26c1",
  "gene": {
    "slug": "cyp26c1",
    "symbol": "CYP26C1",
    "name": "cytochrome P450 family 26 subfamily C member 1",
    "hgnc": "HGNC:20577",
    "summary": null,
    "location": "10q23.33",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000187553",
    "entrezId": 340665,
    "omim": [
      "608428"
    ],
    "uniprot": [
      "Q6V0L0"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "10",
      "start": 93060798,
      "end": 93069540,
      "strand": "+",
      "ensemblTranscript": "ENST00000651965.1",
      "refseqTranscript": "NM_183374.3",
      "ensemblProtein": "ENSP00000498424.1",
      "refseqProtein": "NP_899230.2",
      "exons": [
        {
          "start": 93060798,
          "end": 93061467
        },
        {
          "start": 93062010,
          "end": 93062234
        },
        {
          "start": 93062720,
          "end": 93062995
        },
        {
          "start": 93064381,
          "end": 93064536
        },
        {
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          "end": 93066285
        },
        {
          "start": 93068320,
          "end": 93069540
        }
      ],
      "cds": {
        "start": 93061264,
        "end": 93068697
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "10",
      "start": 94821021,
      "end": 94828454,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 92565169,
      "end": 93565168,
      "genes": [
        {
          "symbol": "IDE",
          "ensemblId": "ENSG00000119912",
          "biotype": "protein_coding",
          "start": 92451684,
          "end": 92574096,
          "strand": "-",
          "slug": "ide"
        },
        {
          "symbol": "KIF11",
          "ensemblId": "ENSG00000138160",
          "biotype": "protein_coding",
          "start": 92574105,
          "end": 92655395,
          "strand": "+",
          "slug": "kif11"
        },
        {
          "symbol": "HHEX",
          "ensemblId": "ENSG00000152804",
          "biotype": "protein_coding",
          "start": 92689893,
          "end": 92695647,
          "strand": "+",
          "slug": "hhex"
        },
        {
          "symbol": "EXOC6",
          "ensemblId": "ENSG00000138190",
          "biotype": "protein_coding",
          "start": 92826831,
          "end": 93059493,
          "strand": "+",
          "slug": "exoc6"
        },
        {
          "symbol": "CYP26A1",
          "ensemblId": "ENSG00000095596",
          "biotype": "protein_coding",
          "start": 93073475,
          "end": 93077885,
          "strand": "+",
          "slug": "cyp26a1"
        },
        {
          "symbol": "MYOF",
          "ensemblId": "ENSG00000138119",
          "biotype": "protein_coding",
          "start": 93306429,
          "end": 93482334,
          "strand": "-",
          "slug": "myof"
        },
        {
          "symbol": "CEP55",
          "ensemblId": "ENSG00000138180",
          "biotype": "protein_coding",
          "start": 93496577,
          "end": 93529096,
          "strand": "+",
          "slug": "cep55"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-blistering-of-the-skin",
        "name": "Abnormal blistering of the skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-blistering-of-the-skin"
      },
      {
        "slug": "abnormal-epidermal-morphology",
        "name": "Abnormal epidermal morphology",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-epidermal-morphology"
      },
      {
        "slug": "abnormal-mast-cell-morphology",
        "name": "Abnormal mast cell morphology",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-mast-cell-morphology"
      },
      {
        "slug": "abnormal-buccal-mucosa-morphology",
        "name": "Abnormality of cheek mucosa",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-buccal-mucosa-morphology"
      },
      {
        "slug": "abnormal-cheek-morphology",
        "name": "Abnormality of the cheek",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-cheek-morphology"
      },
      {
        "slug": "microcephaly",
        "name": "Abnormally small head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/microcephaly"
      },
      {
        "slug": "bitemporal-forceps-marks",
        "name": "Bitemporal forceps marks",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "url": "https://dantelabs.com/traits/bitemporal-forceps-marks"
      },
      {
        "slug": "intracranial-hemorrhage",
        "name": "Bleeding within the skull",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/intracranial-hemorrhage"
      },
      {
        "slug": "cleft-palate",
        "name": "Cleft palate",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/cleft-palate"
      },
      {
        "slug": "cleft-upper-lip",
        "name": "Cleft upper lip",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/cleft-upper-lip"
      },
      {
        "slug": "fragmented-elastic-fibers-in-the-dermis",
        "name": "Fragmented elastic fibers in the dermis",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fragmented-elastic-fibers-in-the-dermis"
      },
      {
        "slug": "nevus",
        "name": "Mole",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/nevus"
      },
      {
        "slug": "scarring",
        "name": "Scarring",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/scarring"
      },
      {
        "slug": "focal-onset-seizure",
        "name": "Seizure affecting one half of brain",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/focal-onset-seizure"
      },
      {
        "slug": "short-chin",
        "name": "Short chin",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/short-chin"
      },
      {
        "slug": "hemangioma",
        "name": "Strawberry mark",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "neoplasm"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hemangioma"
      },
      {
        "slug": "hydrocephalus",
        "name": "Too much cerebrospinal fluid in the brain",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hydrocephalus"
      },
      {
        "slug": "hemiparesis",
        "name": "Weakness of one side of body",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hemiparesis"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}